Heuristic optimization of the p-median problem and population re-distribution

This thesis contributes to the heuristic optimization of the p-median problem and Swedish population redistribution.   The p-median model is the most representative model in the location analysis. When facilities are located to a population geographically distributed in Q demand points, the p-median model systematically considers all the demand points such that each demand point will have an effect on the decision of the location. However, a series of questions arise. How do we measure the distances? Does the number of facilities to be located have a strong impact on the result? What scale of the network is suitable? How good is our solution? We have scrutinized a lot of issues like those. The reason why we are interested in those questions is that there are a lot of uncertainties in the solutions. We cannot guarantee our solution is good enough for making decisions. The technique of heuristic optimization is formulated in the thesis.   Swedish population redistribution is examined by a spatio-temporal covariance model. A descriptive analysis is not always enough to describe the moving effects from the neighbouring population. A correlation or a covariance analysis is more explicit to show the tendencies. Similarly, the optimization technique of the parameter estimation is required and is executed in the frame of statistical modeling. 

Entry, re-location and growth in the Swedish wholesale trade industry

Wholesale trade has an intermediate position between manufacturing and retail in the distributional channel. In modern economies, consumers buy few, if any, products directly from manufacture or producer. Instead, it is a wholesaler, who is in direct contact with producers, buying goods in larger quantities and selling them in smaller quantities to retailers. Traditionally, the main function of a wholesaler has been to push goods along the distributional channel from producer to retailer, or other nonend user. However, the function of wholesalers usually goes beyond the process of the physical distribution of goods. Wholesalers also arrange storage, perform market analyses, promote trade or provide technical support to consumers (Riemers 1998). The existence of wholesalers (and other intermediaries) in the distributional channel is based on the effective and efficient performance of distribution services, that are needed by producers and other members of the supply chain. Producers usually do not enjoy the economies of scale that they have in production, when it comes to providing distributional services (Rosenbloom 2007) and this creates a space for wholesalers or other intermediaries. Even though recent developments in the distributional channel indicate that traditional wholesaling activities now also compete with other supply chain organizations, wholesaling still remains an important activity in many economies (Quinn and Sparks, 2007). In 2010, the Swedish wholesale trade sector consisted of approximately 46.000 firms and generated an annual turnover of 1 300 billion SEK (Företagsstatistiken, Statistics Sweden). In terms of turnover, wholesaling accounts for 20% of the gross domestic product and is thereby the third largest industry. This is behind manufacturing and a composite group of firms in other sectors of the service industry but ahead of retailing. This indicates that the wholesale trade sector is an important part of the Swedish economy. The position of wholesaling is further reinforced when measuring productivity growth. Measured in terms of value added per employee, wholesaling experienced the largest productivity growth of all industries in the Swedish economy during the years 2000 through 2010. The fact that wholesale trade is one of the important parts of a modern economy, and the positive development of the Swedish wholesale trade sector in recent decades, leads to several questions related to industry dynamics. The three topics that will be examined in this thesis are firm entry, firm relocation and firm growth. The main question to be answered by this thesis is what factors influence new firm formation, firm relocation and firm growth in the Swedish wholesale trade sector?

Before the California Highway Commission in re location of Skyline Boulevard, San Francisco to Santa Cruz; supplemental brief for San Lorenzo Valley route from Saratoga Gap to Santa Cruz.

"This brief supersedes the former brief filed by the proponent herein. It embodies all that is to be found in that brief relevant to the questions presented therein."

El CIFOT como apoyo a la gestión gubernamental : efectos socioeconómicos frente a la construcción de la presa Potrerillos.

El objetivo de este estudio es conocer la realidad de los pobladores y su entorno en el área que ahora ocupa el embalse de Potrerillos y su zona de influencia, con diferentes niveles de detalle, para minimizar los efectos negativos sobre la población y conseguir la información imprescindible para la planificación de la zona. Además de la villa de Potrerillos, Cacheuta y Alto Potrerillos se vieron afectadas en su situación social y económica por los cambios originados a partir de la creación del espejo de agua. El CIFOT firma convenio con el Ministerio de Ambiente y Obras Públicas del Gobierno de Mendoza para realizar un trabajo de relevamiento (Junio-Noviembre 1998) para conocer los factores físicos del lugar - aptitudes y susceptibilidades-, la realidad socioeconómica de los pobladores, actividades recreativo – turísticas, infraestructura y equipamiento, como también las relaciones entre localidades, datos que se tienen en cuenta al momento de buscar soluciones para relocalizar la población de la Villa Potrerillos.

Impacto de la obra Presa Potrerillos en los habitantes de la villa y su entorno inmediato

A fines de la década de los noventa se inicia en Mendoza la construcción de la presa Potrerillos, obra hidroeléctrica que tiene el propósito de regular las aguas del río Mendoza, del cual depende el riego y la vida de gran parte del oasis Norte de la provincia. En la serie de beneficios que se esperan de esta obra no figura la población local, que es la directamente afectada. Los resultados obtenidos permiten descubrir aspectos de la realidad y del estilo de vida de Potrerillos hasta el momento desconocidos y que hacen predecir el fuerte impacto socioeconómico que tendrá esta obra, al tener que trasladar población y al constituirse en un polo de atracción para grandes contingentes de turistas ocasionales que buscan aprovechar el espejo de agua o disfrutar del medio natural. El diagnóstico obtenido permite descubrir las alteraciones socioeconómicas a producirse debido a la relocalización de familias, cuyos lotes y viviendas quedarán bajo el agua, aspectos que no se tienen en cuenta en la evaluación de impacto ambiental, en donde se pone el acento en aquellos impactos que pueden llegar a alterar el ecosistema local y regional, pero no en los efectos que ocasionará en la calidad de vida de los lugareños.

Population genetic and dispersal modeling data for Bathymodiolus mussels from the Mid-Atlantic Ridge

The zip folder comprises a text file and a gzipped tar archive. 1) The text file contains individual genotype data for 90 SNPs, 9 microsatellites and the mitochondrial ND4 gene that were determined in deep-sea hydrothermal vent mussels from the Mid-Atlantic Ridge (genus Bathymodiolus). Mussel specimens are grouped according to the population (pop)/location from which they have been sampled (first column). The remaining columns contain the respective allele/haplotype codes for the different genetic loci (names in the header line). The data file is in CONVERT format and can be directly transformed into different input files for population genetic statistics. 2) The tar archive contains NetCDF files with larval dispersal probabilities for simulated annual larval releases between 1998 and 2007. For each simulated vent location (Menez Gwen, Lucky Strike, Rainbow, Vent 1-10) two NetCDF files are given, one for an assumed pelagic larval duration of 1 year and the other one for an assumed pelagic larval duration of 6 months (6m).

Going for god : mobility, place and temporality among evangelical guineans in Lisbon

Tese de doutoramento, Antropologia (Antropologia da Religião e do Simbólico), Universidade de Lisboa, Instituto de Ciências Sociais, 2014

O trânsito de professores durante o processo de criação da Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP): a questão dos ressentimentos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Verso una sociologia della sostenibilità: il caso delle Città in Transizione. Prospettive e limiti di un percorso bottom-up

Oggetto di indagine del lavoro è il movimento ambientalista e culturale delle Città in Transizione che rappresentano esperimenti di ri-localizzazione delle risorse volte a preparare le comunità (paesi, città, quartieri) ad affrontare la duplice sfida del cambiamento climatico e del picco del petrolio. A partire dal Regno Unito, la rete delle Transition Towns si è in pochi anni estesa significativamente e conta oggi più di mille iniziative. L’indagine di tale movimento ha richiesto in prima battuta di focalizzare l’attenzione sul campo disciplinare della sociologia dell’ambiente. L’attenzione si è concentrata sul percorso di riconoscimento che ha reso la sociologia dell’ambiente una branca autonoma e sul percorso teorico-concettuale che ha caratterizzato la profonda spaccatura paradigmatica proposta da Catton e Dunlap, che hanno introdotto nel dibattito sociologico il Nuovo Paradigma Ecologico, prendendo le distanze dalla tradizionale visione antropocentrica della sociologia classica. Vengono poi presentate due delle più influenti prospettive teoriche della disciplina, quella del Treadmill of Production e la più attuale teoria della modernizzazione ecologica. La visione che viene adottata nel lavoro di tesi è quella proposta da Spaargaren, fautore della teoria della modernizzazione ecologica, secondo il quale la sociologia dell’ambiente può essere collocata in uno spazio intermedio che sta tra le scienze ambientali e la sociologia generale, evidenziando una vocazione interdisciplinare richiamata anche dal dibattito odierno sulla sostenibilità. Ma le evidenze empiriche progressivamente scaturite dallo studio di questo movimento che si autodefinisce culturale ed ambientalista hanno richiesto una cornice teorica più ampia, quella della modernità riflessiva e della società del rischio, in grado di fornire categorie concettuali spendibili nella descrizione dei problemi ambientali e nell’indagine del mutamento socio-culturale e dei suoi attori. I riferimenti empirici dello studio sono tre specifiche realtà locali in Transizione: York in Transition per il Regno Unito, Monteveglio (Bo) e Scandiano (Re) in Transizione per l’Italia.

Atypical Mo isotope signatures in eastern Mediterranean sediments

Suboxic sapropel S1 sediments of the eastern Mediterranean carry an untypically light δ98/95Mo signal, being even lighter than oxic Mn-enriched sediments and Mn-crusts/nodules, which were previously thought to carry the lightest Mo isotope values. The evaluation and comparison of oxic S1, diagenetically overprinted oxic S1, and suboxic S1 sediments indicates that this light isotope signal is primarily an oxic signal that has been overprinted by secondary diagenetic processes occurring after sediment burial. Such secondary processes bear the potential of additional Mo isotope fractionation in particular in non-steady state diagenetic environments that involve the discontinuous re-location of the redox boundary.

1906 Polk's Medical Register and Directory of North America (Texas Portion Only)

List of Physicians and Surgeons arranged by location, giving post office address with population and location, the School practiced, date and college of graduation, all the existing and extinct medical colleges in North America, with locations, officers, number of professors, lecturers, demonstrators, etc., the various medical societies, penal, reformatory and charitable state institutions, hospitals, sanitariums, dispensaries, asylums and other medical institutions, boards of health, boards of medical examiners, health officers at principal points, the laws of registration and other laws relating to the profession, medical journals with names of editors, frequency of publication and subscription rates, medical libraries, a therapeutic classification of American health resorts, mineral springs, official list of officers of the medical departments of the U.S. Army, Navy and Marine Hospital Service, the U.S. Indian Service, roster of examining surgeons of the U.S. Pension Department, a descriptive sketch of each state, territory and province, embodying such matters as location, boundary, extent in miles and acres, latitude and longitude, statistics relating to climate, temperature, rate of mortality, etc. Full particulars of all national and inter-state associations and societies relating to medicine and surgery, and an INDEX TO THE PHYSICIANS OF THE UNITED STATES. Arranged alphabetically, with the number of the page and column in which the name appears.

1902 Polk's Medical Register and Directory of the United States and Canada (Texas portion only)

List of Physicians and Surgeons arranged by states and provinces, giving post office address with population and location, the School practiced, date and college of graduation, all the existing and extinct medical colleges in the United States and Canada, with locations, officers, number of professors, lecturers, demonstrators, etc., the various medical societies, state prisons, hospitals, sanitariums, dispensaries, asylums and other medical institutions, boards of health, boards of medical examiners, a synopsis of the laws of registration and other laws relating to the profession, medical journals with names of editors, frequency of publication and subscription rates, medical libraries, mineral springs, official list of officers of the medical departments of the U.S. Army, Navy and Marine Hospital Service, roster of examining surgeons of the U.S. Pension Department, a descriptive sketch of each state, territory and province, embodying such matters as location, boundary, extent in miles and acres, latitude and longitude, statistics relating to climate, temperature, rate of mortality, number of deaths from consumption, etc. full particulars of all national associations and societies relating to medicine and surgery, and an INDEX TO THE PHYSICIANS OF THE UNITED STATES. Arranged alphabetically, with the number of the page on which the name appears.

On the Evolution of the Spatial Economy with Multi-unit/Multi-plant Firms: The Impact of IT Development

This paper examines how the decline of communication costs between management and production facilities within firms and the decrease in trade costs of manufactured goods affect the spatial organization of a two-region economy with multi-unit/multi-plant firms. The development of information technology decreases the costs of communication and trade costs. Thus, the fragmentation of firms is promoted. Our result indicates that, with decreasing communication costs, firms producing low trade-cost products (such as consumer electronics) tend to concentrate their manufacturing plants in low wage countries. In contrast, firms producing high trade-cost products (such as automobiles) tend to have multiple plants serving to segmented markets, even in the absence of wage differentials.

Globalization and the Evolution of the Supply Chain: who gains and who loses?

This paper focuses on two distinct facets of globalization: the decrease in the trade costs of goods and the decline of communication costs between headquarters and production facilities within firms. When the unskilled have about the same wage in the two regions, the decrease of these costs fosters the gradual agglomeration of plants in the core region accommodating the headquarters. By contrast, when the wage gap is significant, the process of integration eventually triggers the re-location of plants into the periphery. In particular, when the process of re-location is driven by falling communication costs, the welfare of all workers living in the core goes down whereas the welfare of those who reside in the periphery rises.

Retinal microglia are activated by systemic fungal infection

Purpose: To determine whether systemic fungal infection could cause activation of retinal microglia and therefore could be potentially harmful for patients with retinal degenerative diseases. Methods: Activation of retinal microglia was measured in a model of sublethal invasive candidiasis in C57BL/6J mice by (i) confocal immunofluorescence and (ii) flow cytometry analysis, using anti-CD11b, anti-Iba1, anti-MHCII and anti-CD45 antibodies. Results: Systemic fungal infection causes activation of retinal microglia, with phenotypic changes in morphology, surface markers expression, and microglial re-location in retinal layers. Conclusions: As an excessive or prolonged microglial activation may lead to chronic inflammation with severe pathological side effects, causing or worsening the course of retinal dystrophies, a systemic infection may represent a risk factor to be considered in patients with ocular neurodegenerative diseases, such as diabetic retinopathy, glaucoma, age-related macular degeneration or retinitis pigmentosa.