910 resultados para Perry, John.


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The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n = 8,531) and sought validation of the lead single nucleotide polymorphisms (SNPs) in 5 additional cohorts (n = 6,202). Five SNPs were genome-wide significant in their relationship with adiponectin (P< or =5x10(-8)). We then tested whether these 5 SNPs were associated with risk of T2D and CHD using a Bonferroni-corrected threshold of P< or =0.011 to declare statistical significance for these disease associations. SNPs at the adiponectin-encoding ADIPOQ locus demonstrated the strongest associations with adiponectin levels (P-combined = 9.2x10(-19) for lead SNP, rs266717, n = 14,733). A novel variant in the ARL15 (ADP-ribosylation factor-like 15) gene was associated with lower circulating levels of adiponectin (rs4311394-G, P-combined = 2.9x10(-8), n = 14,733). This same risk allele at ARL15 was also associated with a higher risk of CHD (odds ratio [OR] = 1.12, P = 8.5x10(-6), n = 22,421) more nominally, an increased risk of T2D (OR = 1.11, P = 3.2x10(-3), n = 10,128), and several metabolic traits. Expression studies in humans indicated that ARL15 is well-expressed in skeletal muscle. These findings identify a novel protein, ARL15, which influences circulating adiponectin levels and may impact upon CHD risk.

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Top Row: Tom Owens, Jim Capoferi, Dan Cooperrider, Dave Chapman, Scott Anderson, Chris Martucci, Steve Perry, John McEldowney, trainer Al Green

Middle Row: Mike Bryant, Steve Howe, Rick Leach, Mike Parker, bob Wasilewski, Craig McGinnis, Bill Stennett, George Foussianes

Top Row: Jim Berra, Greg Lane, Ted Mahan, coach Moby Benedict, Mark Grenkoski, Steve Seyferth, asst. coach Pete Ross, mngr. Frank Young

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Mode of access: Internet.

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"A guide to Florida fishing" (originally compiled by E.L. Brewton and revised by Junior chamber of commerce of Daytona Beach, and copyright in their names in 1936 and 1937): p. 281-300.

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Mode of access: Internet.

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Cover title.

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Lettered on cover: "Perry", experiences of a pioneer.

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Published also in the Riverside literature series.

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Reproduced from a copy in ... the University of Washington Library.

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We study the stability of D >= 7 asymptotically flat black holes rotating in a single two-plane against tensor-type gravitational perturbations. The extensive search of quasinormal modes for these black holes did not indicate any presence of growing modes, implying the stability of simply rotating Myers-Perry black holes against tensor-type perturbations.

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