984 resultados para Per Opportunity Measures


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Thesis (Ph.D.)--University of Washington, 2016-06

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Study Objectives: To test the effects of exercise training on sleep and neurovascular control in patients with systolic heart failure with and without sleep disordered breathing. Design: Prospective interventional study. Setting: Cardiac rehabilitation and exercise physiology unit and sleep laboratory. Patients: Twenty-five patients with heart failure, aged 42 to 70 years, and New York Heart Association Functional Class I-III were divided into 1 of 3 groups: obstructive sleep apnea (n = 8), central sleep apnea (n 9) and no sleep apnea (n = 7). Interventions: Four months of no-training (control) followed by 4 months of an exercise training program (three 60-minute, supervised, exercise sessions per week). Measures and Results: Sleep (polysomnography), microneurography, forearm blood flow (plethysmography), peak VO(2). and quality of life were evaluated at baseline and at the end of the control and trained periods. No significant changes occurred in the control period. Exercise training reduced muscle sympathetic nerve activity (P < 0.001) and increased forearm blood flow (P < 0.01), peak VO(2) (P < 0.01), and quality of life (P < 0.01) in all groups, independent of the presence of sleep apnea. Exercise training improved the apnea-hypopnea index, minimum O(2) saturation, and amount stage 3-4 sleep (P < 0.05) in patients with obstructive sleep apnea but had no significant effects in patients with central sleep apnea. Conclusions. The beneficial effects of exercise training on neurovascular function, functional capacity, and quality of life in patients with systolic dysfunction and heart failure occurs independently of sleep disordered breathing. Exercise training lessens the severity of obstructive sleep apnea but does not affect central sleep apnea in patients with heart failure and sleep disordered breathing.

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Le thème de la motivation au travail en lien avec la performance des employés captive l’intérêt des théoriciens, des chercheurs, des praticiens et des gestionnaires depuis déjà près d’un siècle. L’engouement pour l’étude de ces concepts a permis de faire des avancées scientifiques notables permettant de mieux éclairer la pratique. Cependant, on constate que la popularité de la motivation présente également certains enjeux. Notamment, la pluralité des théories rend le domaine presque étourdissant par ses connaissances éparses et ses résultats équivoques. En premier lieu, cette thèse présente une méta-analyse multithéorique réalisée à partir d’études effectuées sur le terrain examinant les liens entre la motivation au travail et la performance des travailleurs entre 1985 et 2010. Les résultats de ce bilan nous indiquent que, peu importe la théorie motivationnelle employée, la force et la direction de la relation motivation-performance sont similaires plutôt que différentes. Parmi les variables modératrices examinées, seule la source des mesures s’est révélée significative indiquant que la relation entre les variables d’intérêt est plus forte lorsque les mesures proviennent de la même source – dans notre étude elles s’avèrent toutes autodéclarées – comparativement à lorsqu’elles sont recueillies auprès de sources différentes. En second lieu, une étude en laboratoire a permis d’observer que la motivation peut évoluer sur une période très courte, soit de moins de 90 minutes, à partir de 3 mesures de motivation réparties dans le temps d’expérimentation. Plus spécifiquement, l’étude de la motivation par type et par quantité, en considérant le facteur temps, nous renseigne que la motivation intrinsèque a augmenté tandis que la motivation extrinsèque et l’amotivation ont connu une diminution. Cette étude, considérant une perspective multidimensionnelle et dynamique de la motivation, telle que proposée par le cadre conceptuel de la théorie de l’autodétermination, montre que l’évolution de la motivation de tous les participants à l’étude est semblable, peu importe leur performance. En plus de permettre l’avancement des connaissances dans le domaine de la motivation et de la performance au travail, cette thèse se démarque à plusieurs égards. D’un côté, il s’agit de la première méta-analyse multithéorique de la motivation qui soit réalisée. De l’autre côté, l’étude en laboratoire a examiné simultanément, le type et la quantité de la motivation à l’aide d’un devis à mesures répétées alors que la majorité des études se concentrent soit sur la quantité, soit sur le type et néglige souvent de considérer la variable temps. En outre, cette étude en laboratoire a été réalisée à partir d’une activité à haut potentiel de validité écologique, s’apparentant à une tâche de sélection de candidats en ressources humaines. En somme, cette thèse apporte un éclairage intéressant tant sur le plan des connaissances concernant les variables modératrices déterminantes impliquées dans les relations motivation-performance et sur le plan du rythme des variations des types de motivation que sur le plan de l’utilisation optimale et complémentaire de techniques de recherche sophistiquées. L’ensemble des recommandations découlant de ces deux études concernant la recherche et l’intervention est présenté en conclusion.

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We put together the different conceptual issues involved in measuring inequality of opportunity, discuss how these concepts have been translated into computable measures, and point out the problems and choices researchers face when implementing these measures. Our analysis identifies and suggests several new possibilities to measure inequality of opportunity. The approaches are illustrated with a selective survey of the empirical literature on income inequality of opportunity.

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This paper proposes an ex-post measure of inequality of opportunity in France and its regions by assessing the inequality between individuals exerting the same effort. To this end, we define a fair income that fulfils ex-post equality of opportunity requirements. Unfairness is measured by an unfair Gini based on the distance between the actual income and the fair income. Our findings reveal that the measures of ex-post inequality of opportunity largely vary across regions, and that this is due to di_erences in reward schemes and in the impact of the non responsibility factors of income. We find that most regions have actual incomes closer to fair incomes than to average income, excepted Ile de France where the actual income looks poorly related to effort variables. Finally, we find that income inequality and inequality of opportunity are positively correlated among regions.

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Nell’attuale contesto, caratterizzato da un’elevata attenzione alla qualità e alla sicurezza degli alimenti e alle soluzioni tese a garantirli, l’implementazione di sistemi microelettronici per il controllo del prodotto attraverso supporti miniaturizzati e a basso costo può risultare un’opportunità strategica. Oggetto della ricerca di dottorato sono stati lo studio dell’utilizzo di sensori e strumentazione innovativi per la misurazione ed il controllo di parametri ambientali di conservazione di prodotti alimentari e per la loro identificazione mediante la tecnologia della radiofrequenza. Allo scopo è stato studiato il contesto in cui operano gli attori principali della filiera agroalimentare ed è stata sviluppata un’idea di etichetta progettata per essere in grado di emettere attivamente segnale di allarme in caso di necessità (etichetta RFID intelligente semi-passiva). Il prototipo di chip, realizzato in via sperimentale, è stato validato positivamente, sia come strumento di misura, sia in termini di prestazione nel caso studio del monitoraggio della conservazione di un prodotto alimentare in condizioni controllate di temperatura e radiazione luminosa. Le significative evidenze analitiche di reazioni di degradazione dello stato qualitativo del prodotto, quali analisi di pH e colore, raccolte durante il periodo di osservazione di 64 giorni, hanno trovato riscontro con le misure rilevate dal chip prototipo. I risultati invitano ad individuare un partner industriale, con il quale sperimentare l’applicazione della tecnologia proposta.

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Widely used ''purchasing power parity'' comparisons of per capita GDP are not true quantity indexes and are subject to systematic substitution bins. This bias may distort measurement of convergence and divergence. Extending Varian's nonparametric construction of a true index gives the set of true indexes, including the new Ideal Afriat Index. These indexes are utility-consistent and independent of arbitrary reference price vectors. We establish bounds on the dispersion of true multilateral indexes, hence bounds on convergence. International price indexes understate both true GDP dispersion and, where prices are converging over time, the rate of true quantity convergence.

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Six of the short dietary questions used in the 1995 National Nutrition Survey (see box below) were evaluated for relative validity both directly and indirectly and for consistency, by documenting the differences in mean intakes of foods and nutrients as measured on the 24-hour recall, between groups with different responses to the short questions. 1. Including snacks, how many times do you usually have something to eat in a day including evenings? 2. How many days per week do you usually have something to eat for breakfast? 3. In the last 12 months, were there any times that you ran out of food and couldn’t afford to buy more? 4. What type of milk do you usually consume? 5. How many serves of vegetables do you usually eat each day? (a serve = 1/2 cup cooked vegetables or 1 cup of salad vegetables) 6. How many serves of fruit do you usually eat each day? (a serve = 1 medium piece or 2 small pieces of fruit or 1 cup of diced pieces) These comparisons were made for males and females overall and for population sub-groups of interest including: age, socio-economic disadvantage, region of residence, country of birth, and BMI category. Several limitations to this evaluation of the short questions, as discussed in the report, need to be kept in mind including: · The method for comparison available (24-hour recall) was not ideal (gold standard); as it measures yesterday’s intake. This limitation was overcome by examining only mean differences between groups of respondents, since mean intake for a group can provide a reasonable approximation for ‘usual’ intake. · The need to define and identify, post-hoc, from the 24-hour recall the number of eating occasions, and occasions identified by the respondents as breakfast. · Predetermined response categories for some of the questions effectively limited the number of categories available for evaluation. · Other foods and nutrients, not selected for this evaluation, may have an indirect relationship with the question, and might have shown stronger and more consistent responses. · The number of responses in some categories of the short questions eg for food security may have been too small to detect significant differences between population sub-groups. · No information was available to examine the validity of these questions for detecting differences over time (establishing trends) in food habits and indicators of selected nutrient intakes. By contrast, the strength of this evaluation was its very large sample size, (atypical of most validation studies of dietary assessment) and thus, the opportunity to investigate question performance in a range of broad population sub-groups compared with a well-conducted, quantified survey of intakes. The results of the evaluation are summarised below for each of the questions and specific recommendations for future testing, modifications and use provided for each question. The report concludes with some general recommendations for the further development and evaluation of short dietary questions.

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This work was undertaken in the municipality of Pedro de Toledo (São Paulo State, Brazil) in 1987, to clarify aspects related to the transmission levels of Schistosoma mansoni in a human population where the snail host is Biomphalaria tenagophila. Since 1980 a control programme has been undertaken in this municipality. Urban and rural populations (4,719 subjects) were submitted to faecal examinations (Kato-Katz method). The overall prevalence rate was 4.8% being higher in males (6.2%) and also in the rural zone (5.8%). The geometric mean of S. mansoni eggs was 35.1 eggs per gramme of faeces (epg). Approximately 80.0% of the carriers presented less than 100 epg and only 20 individuals (9.0%) eliminated more than half of total eggs. The highest index of potencial contamination (IPC) was in the age group of 5 to 20 years (57.6%). Two thirds of the investigated patients (207) were autochthonous of Pedro de Toledo. The geographical distribution of the carriers showed a clear aggregation of the autochthonous cases and a close association between human contact sites and breeding places of B. tenagophila. This study shows that schistosomiasis subjects were not randomly aggregated, the youngsters should be the main target in the prophylaxis, and the efficacy of the control programme.

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Finfish pots have emerged as a “responsible” gear, when used in combination with conservational and technical measures to sustain fisheries. Previous trials in Irish waters have offered no published reported data and so three designs tested in the current study provide new information on this gear. The most successful traps in terms of fish catch were rigid steel framed rectangular pots used to target Conger eel. Although commercial yield was low (0.2 per trap haul), potential existed for a viable pot fishery. Deployment and storage of Norwegian floating pots was conducted with relative ease but performance in the water was poor resulting in loss of gear. Catch returns were notable even though effort was restricted as mega-faunal by-catch was a problem, which lead to ending this trial. From these initial trials it was evident that catch rates were low compared to established Norwegian fisheries (3.6 cod per pot), which resulted in the utilisation of pots, already established in the crustacean fishery, to find species readily accessible to pot capture. Although fished and designed differently, these gears provided an opportunity to establish the benefits of pot fishing to fish quality and to determine the effects on by-catch. The fishing effects of three catching methods (pots, angling and trawl) and the effects of air exposure on the physiological status of a common by-catch, the lesser spotted dogfish Scyliorhinus canícula (L.) were examined using a range of physiological biomarkers (plasma catecholamine, glucose, lactate, muscle pH and muscle lactate). Physiological responses of fish to an emersion stress regime resulted in a significant metabolic disturbance in groups, but may not have weakened the overall health of these fish, as signified in the revival of some metabolites. Plasma glucose and lactate concentrations did not however recovery to baseline levels indicating that to achieve an accurate profile, responses should be determined by a suite of biomarkers. Responses did not demonstrate that samples from the pots were significantly less stressed than for the other two methods; angling and trawling, which are in contrast to many other studies. Employment of finfish potting therefore in Irish waters needs further consideration before further promotion as a more responsible method to supplement or replace established techniques.

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L'ús de recursos d'informació electrònics de pagament continuarà creixent i en alguns casos es convertiran en els instruments principals o exclusius d’accés al contingut. L'entorn electrònic, com es posa de manifest a través del World Wide Web, ofereix una oportunitat de millorar la mesura de l'ús d'aquests recursos. En el terreny electrònic podem determinar acuradament a quina informació s'està accedint i quina informació s'utilitza. Sense infringir cap norma de privacitat o confidencialitat podem reforçar la nostra comprensió sobre l'ús de la informació de manera espectacular.

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Measuring the intensity of sexual selection is of fundamental importance to the study of sexual dimorphism, population dynamics, and speciation. Several indices, pools of individuals, and fitness proxies are used in the literature, yet their relative performances are strongly debated. Using 12 independent common lizard populations, we manipulated the adult sex ratio, a potentially important determinant of the intensity of sexual selection at a particular time and place. We investigated differences in the intensity of sexual selection, as estimated using three standard indices of sexual selection-the standardized selection gradient (β'), the opportunity of selection (I), and the Bateman gradient (βss)--calculated for different pools of individuals and different fitness proxies. We show that results based on estimates of I were the opposite of those derived from the other indices, whereas results based on estimates of β' were consistent with predictions derived from knowledge about the species' mating system. In addition, our estimates of the strength and direction of sexual selection depended on both the fitness proxy used and the pool of individuals included in the analysis. These observations demonstrate inconsistencies in distinct measures of sexual selection and underscore the need for caution when comparing studies and species.

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En aquest treball, s’ha dissenyat un mòdul d’acondicionament a fi de millorar les mesures de conductivitat realitzades amb un AFM (Microscopi de Forces Atòmiques). L’equip actual disposa d’un preamplificador de baix soroll amb un guany de 10 10V/A. Donat que els corrents que es pretenen mesurar són extremadament petits (~pA), s’ha dissenyat un filtre per eliminar diferents fonts de soroll, com ara el soroll que introdueix la xarxa elèctrica a 50Hz. Es pretén reduir aquesta component freqüencial un factor mínim de 10 (20dB). També s’ha afegit un filtre passa baixos per eliminar els soroll que es troba fora de l’amplada de banda del preamplificador. S’ha introduït una etapa d’amplificació de guany variable: 1, 10 i 100 per augmentar la flexibilitat de l’equip i finalment també s’ha dissenyat una etapa per eliminar la tensió d’offset d’aquest amplificador. L’abast del treball anirà des del disseny fins la implementació final sobre una placa PCB.

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The paradox of autonomy is about whether self-rule accommodates or exacerbates armed conflict. This study attempts to unpack the puzzle examining the effectiveness of territorial autonomy as a state response to self-determination conflicts throughout the world. It challenges the conflict-inducing features of autonomy arguing that territorial autonomy can mitigate armed conflict by channeling group grievances into peaceful forms of protest. Thus, this study aims at arriving at a comprehensive theory that identifies which factors are responsible for violent escalation of conflicts grounded in self-determination demands. By using the concepts of opportunity structures and willingness dimension, this study shows that conflict escalation only takes place when minorities with greater bargaining power vis-à-vis the center, in contexts of high levels of economic inequality within dyad, are mobilized around autonomy and separatist demands.

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The Road Safety Authority has responsibility for co-ordinating the development of Ireland’s Road Safety Strategy.  The Government’s road safety target of no more than 252 deaths per annum by the end of 2012 was achieved in 2009, when the number of road collision deaths in Ireland fell to 239.  The reduction in the number of fatalities was achieved through robust actions in terms of education and awareness, road engineering, and enforcement, including significant legislative milestones.  The challenge is now to ensure that the impact of these measures on collision levels is sustained and enhanced into the future through continuous education, enforcement and road engineering measures and initiatives. IPH welcomes the opportunity to respond to this consultation given the significant burden of injury, disability and mortality associated with road traffic collisions on the island of Ireland.  IPH supports the development of evidence-based strategies and actions which can maintain a transport system, in which the safety of all road users is paramount.