984 resultados para PAG


Relevância:

20.00% 20.00%

Publicador:

Resumo:

El Programa de adaptaci??n curricular grupal tiene como finalidad compensar los d??ficit del alumnado, desarrollando sus capacidades generales mediante una metodolog??a y unos contenidos adaptados a sus caracter??sticas y necesidades. Se dirige a alumnos con dificultades generalizadas de aprendizaje y que, a juicio de la junta de profesores del grupo al que pertenezcan y del departamento de orientaci??n, se encuentren en situaci??n de no alcanzar los objetivos de ESO cursando el curr??culum ordinario. El programa se apoya en el tratamiento interdisciplinar de determinadas materias, una selecci??n de ??reas espec??ficas que, con las adaptaciones necesarias se consideren adecuadas para elaborar los programas individualizados de los alumnos seleccionados buscando la m??xima normalizaci??n y la flexibilidad en relaci??n con el curr??culum ordinario.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

El programa de adaptaciones grupales se considera una medida excepcional de atenci??n a la diversidad de sola aplicaci??n agotadas las medidas ordinarias. Se incluye en el proyecto curricular y en el plan anual. Va dirigido a alumnos absentistas y con grandes desfases curriculares. Los programas duran un curso acad??mico y, excepcionalmente, dos. En el libro se recogen los presentados en el seminario por nueve institutos de secundaria de la Regi??n de Murcia.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Resumen basado en el de la publicaci??n

Relevância:

20.00% 20.00%

Publicador:

Resumo:

It is widely acknowledged that the indoleamine neurotransmitter serotonin (5-HT) plays a dual role in the regulation of anxiety, a role that in part depends upon neuroanatomical locus of action. Thus, whereas stimulation of 5-HT1A or 5-HT2 receptors in the limbic forebrain (amygdala, hippocampus) enhances anxiety-like responding in rodents, activation of corresponding receptor populations in the midbrain periaqueductal grey (PAG) more often than not reduce anxiety-like behaviour. The present study specifically concerns the anxiety-modulating influence of 5-HT2 receptors within the mouse PAG. Experiment 1 assessed the effects of intra-PAG infusions of the 5-HT2B/2C receptor agonist mCPP (0, 0.03, 0.1 or 0.3 nmol/0.1 mu l) on the behaviour of mice exposed to the elevated plus-maze. As mCPP acts preferentially at 5-HT2B and 5-HT2C receptors, Experiment 2 investigated its effects in animals pretreated with ketanserin, a preferential 5-HT2A/2C receptor antagonist. In both cases, test sessions were videotaped and subsequently, scored for anxiety-like behaviour (e.g., percentage of open arm entries and percentage of open arm time) as well as general locomotor activity (closed arm entries). The results of Experiment I showed that mCPP microinfusions (0.03 and 0.1 nmol) into the PAG of mice decreased behavioural indices of anxiety without significantly altering general activity measures. In Experiment 2, the anxiolytic-like profile of intra-PAG mCPP (0.03 nmol) was substantially attenuated by intra-PAG pretreatment with an intrinsically inactive dose of the preferential 5-HT2A/2C receptor antagonist, ketanserin (10 nmol/0.1 mu l). Together, these data suggest that 5HT(2C) receptor populations within the midbrain PAG play an inhibitory role in plus-maze anxiety in mice. (C) 2007 Elsevier B.V. All rights reserved.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The midbrain dorsal periaqueductal gray (DPAG) is part of the brain defensive system involved in active defense reactions to threatening stimuli. Corticotrophin releasing factor (CRF) is a peptidergic neurotransmitter that has been strongly implicated in the control of both behavioral and endocrine responses to threat and stress. We investigated the effect of the nonspecific CRF receptor agonist, ovine CRF (oCRF), injected into the DPAG of mice, in two predator-stress situations, the mouse defense test battery (MDTB), and the rat exposure test (RET). In the MDTB, oCRF weakly modified defensive behaviors in mice confronted by the predator (rat); e.g. it increased avoidance distance when the rat was approached and escape attempts (jump escapes) in forced contact. In the RET, drug infusion enhanced duration in the chamber while reduced tunnel and surface time, and reduced contact with the screen which divides the subject and the predator. oCRF also reduced both frequency and duration of risk assessment (stretch attend posture: SAP) in the tunnel and tended to increase freezing. These findings suggest that patterns of defensiveness in response to low intensity threat (RET) are more sensitive to intra-DPAG oCRF than those triggered by high intensity threats (MDTB). Our data indicate that CRF systems may be functionally involved in unconditioned defenses to a predator, consonant with a role for DPAG CRF systems in the regulation of emotionality. (c) 2006 Elsevier B.V. All rights reserved.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Analisaremos nesta pesquisa as linhas do naturalismo proposto por Marques de Carvalho no romance O Pagé, que veio à público como folhetim pelo periódico A República em janeiro de 1887, tendo por subtítulo a expressão “romance naturalista.” Que naturalismo era esse? Quem era Marques de Carvalho antes da publicação de seu mais conhecido romance Hortência? Com esses questionamentos, seguiremos a trilha do intelectual por trás dos periódicos onde atuou como redator, assim como, os debates e conflitos em que se envolveu. Adentraremos o campo literário paraense do final do Oitocentos, para, a partir das disputas em seu interior, enxergarmos as forças de legitimação de um modo de pensar. Nesse caso, a visão de mundo de Marques de Carvalho.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This work tries to show to the reader a more mystical side of Excalibur and its importance to the Arthurian myth. As its origin is pagan indigenous to the legends of the Celtic people, they will be briefly introduced to the reader so that they can realize the time in which the Celts lived, who they were and a little about how they acted in accordance with their culture . It will also be exposed a brief overview about the character of King Arthur and all the changes that it has passed through according to what suited to the culture of each time. Two legends about Excalibur will be analyzed, so that both points of view Pagan and Christian can be disclosed according to the myths and theoretical texts used as a basis for this work. Finally, several analyzis about the sword will be brought to the reader so they can understand the complexity of myths and symbols that the Celts have left as a legacy

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This work tries to show to the reader a more mystical side of Excalibur and its importance to the Arthurian myth. As its origin is pagan indigenous to the legends of the Celtic people, they will be briefly introduced to the reader so that they can realize the time in which the Celts lived, who they were and a little about how they acted in accordance with their culture . It will also be exposed a brief overview about the character of King Arthur and all the changes that it has passed through according to what suited to the culture of each time. Two legends about Excalibur will be analyzed, so that both points of view Pagan and Christian can be disclosed according to the myths and theoretical texts used as a basis for this work. Finally, several analyzis about the sword will be brought to the reader so they can understand the complexity of myths and symbols that the Celts have left as a legacy

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Motor cortex stimulation is generally suggested as a therapy for patients with chronic and refractory neuropathic pain. However, the mechanisms underlying its analgesic effects are still unknown. In a previous study, we demonstrated that cortical stimulation increases the nociceptive threshold of naive conscious rats with opioid participation. In the present study, we investigated the neurocircuitry involved during the antinociception induced by transdural stimulation of motor cortex in naive rats considering that little is known about the relation between motor cortex and analgesia. The neuronal activation patterns were evaluated in the thalamic nuclei and midbrain periaqueductal gray. Neuronal inactivation in response to motor cortex stimulation was detected in thalamic sites both in terms of immunolabeling (Zif268/Fos) and in the neuronal firing rates in ventral posterolateral nuclei and centromedian-parafascicular thalamic complex. This effect was particularly visible for neurons responsive to nociceptive peripheral stimulation. Furthermore, motor cortex stimulation enhanced neuronal firing rate and Fos immunoreactivity in the ipsilateral periaqueductal gray. We have also observed a decreased Zif268, delta-aminobutyric acid (GABA), and glutamic acid decarboxylase expression within the same region, suggesting an inhibition of GABAergic interneurons of the midbrain periaqueductal gray, consequently activating neurons responsible for the descending pain inhibitory control system. Taken together, the present findings suggest that inhibition of thalamic sensory neurons and disinhibition of the neurons in periaqueductal gray are at least in part responsible for the motor cortex stimulation-induced antinociception. (C) 2012 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Coronatio Maximiliani I. Archiducis Austriae in Regem Romanorum Caroli Quinti electio per Georgium Sabinum descripta. -- Eiusdem coronatio per Hartmannum Maurum. -- Maximiliani II. per Adamum & Nicolaum Heydenos fratres. -- Matthiae Austriaci in Regem Hungariae per Doct. Iessenium Eq. Vng. -- Eiusdem in Regem Romanorum. -- Inuestitura regalium electoralis dignitatis Mauritii Ducis Saxoniae, à Mamerano Lucemburgo descripta. -- Onuphrii Panuinii De comitiis Imperatoriis liber. -- Michaelis Beutheri De septemuiratu principum electorum sententia. -- Aurea bulla Caroli IV. -- Electio & coronatio Pontificis Romani.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Includes bibliographical footnotes.