Development of an Expert System for Forecasting Frost on Bridges and Roadways in Iowa, HR-305, 1991

An expert system has been developed that provides 24 hour forecasts of roadway and bridge frost for locations in Iowa. The system is based on analysis of frost observations taken by highway maintenance personnel, analysis of conditions leading to frost as obtained from meteorologists with experience in forecasting bridge and roadway frost, and from fundamental physical principles of frost processes. The expert system requires the forecaster to enter information on recent maximum and minimum temperatures and forecasts of maximum and minimum air temperatures, dew point temperatures, precipitation, cloudiness, and wind speed. The system has been used operationally for the last two frost seasons by Freese-Notis Associates, who have been under contract with the Iowa DOT to supply frost forecasts. The operational meteorologists give the system their strong endorsement. They always consult the system before making a frost forecast unless conditions clearly indicate frost is not likely. In operational use, the system is run several times with different input values to test the sensitivity of frost formation on a particular day to various meteorological parameters. The users comment. that the system helps them to consider all the factors relevant to frost formation and is regarded as an office companion for making frost forecasts.

De iure Augusti imperatoris exigendi a Judaeis aurum voronarium annumque censum vulgo numum oblatorium dictum, oratio inauguralis ... nunc cum notis perpetuis

ill. a Io. Georg. Pertsch

Institutio epistolaris hebraica sive de conscribendis epistolis hebraicis liber, cum epistolarum hebraicarum centuria, ex quibus quinquaginta punctatae, latine explicatae et notis illustratae sunt : accessit appendix variarum epistolarum R. Majemonis et aliorum ejus seculi excellentium Rabbinorum

Johannes Buxtorf

Henr. Bened. Starki Lux Ebraea ex nouissimis Principiis cum perpetuis Notis Criticis atque Rationibus Accensa

Erscheinungsjahr lt. "Katalog der Judaica und Hebraica, Frankfurt am Main, 1932". - Teilw. in hebr. Schr.

Chrestomathia Rabbinica et Chaldaica : cum notis grammaticis, historicis, theologicis, glossaris et lexico abbreviatarum, quae in Hebraeorum scriptis passim occurrunt

auctore Joanne Theodoro Beelen

De re grammatica Hebraeorum opus, in gratiam studiosorum linguae sanctae methodo quam facilima conscriptum : Accessit etiam liber de Notis Hebraeorum ab eodem Quinquarboreo ... media parte auctus, ...Hebraicari volentibus ... utilis

auctore Iohanne Quinquarboreo

De re grammatica Hebraeorum opus, in gratiam studiosorum linguae sanctae methodo quam facilima conscriptum : Accessit etiam liber de Notis Hebraeorum ab eodem Quinquarboreo ... media parte auctus, ...Hebraicari volentibus ... utilis

auctore Iohanne Quinquarboreo

Moses et Aaron cum notis Joh. Henr. Hottingeri

Vorlage d. Digitalisats aus d. Besitz d. Theol. Hochschule St. Georgen

Biblia Hebraica : Cum Notis Hebraicis Et Lemmatibus Latinis, ex recensione Danielis Ernesti Jablonski, Sereniss. Elect. Brandenb. a Sacris & Ecclesiarr. Unit. FFrr. per Polon. maior. & Pruss. Senioris: Ad calcem subiungitur Clar. Viri Joh. Leusden Catalogus posthumus 2294. selectorum versuum, quibus omnes voces V.T. continentur

Edita Opera & Impensis Johannis Henrici Knebelii, Collegae Gymnasii Electoralis Joachimici

Obesity And Inflammation And The Effect On The Hematopoietic System.

Bone marrow is organized in specialized microenvironments known as 'marrow niches'. These are important for the maintenance of stem cells and their hematopoietic progenitors whose homeostasis also depends on other cell types present in the tissue. Extrinsic factors, such as infection and inflammatory states, may affect this system by causing cytokine dysregulation (imbalance in cytokine production) and changes in cell proliferation and self-renewal rates, and may also induce changes in the metabolism and cell cycle. Known to relate to chronic inflammation, obesity is responsible for systemic changes that are best studied in the cardiovascular system. Little is known regarding the changes in the hematopoietic system induced by the inflammatory state carried by obesity or the cell and molecular mechanisms involved. The understanding of the biological behavior of hematopoietic stem cells under obesity-induced chronic inflammation could help elucidate the pathophysiological mechanisms involved in other inflammatory processes, such as neoplastic diseases and bone marrow failure syndromes.

The Value Of The 2005 International Society Of Urological Pathology (isup) Modified Gleason Grading System As A Predictor Of Biochemical Recurrence After Radical Prostatectomy.

To compare time and risk to biochemical recurrence (BR) after radical prostatectomy of two chronologically different groups of patients using the standard and the modified Gleason system (MGS). Cohort 1 comprised biopsies of 197 patients graded according to the standard Gleason system (SGS) in the period 1997/2004, and cohort 2, 176 biopsies graded according to the modified system in the period 2005/2011. Time to BR was analyzed with the Kaplan-Meier product-limit analysis and prediction of shorter time to recurrence using univariate and multivariate Cox proportional hazards model. Patients in cohort 2 reflected time-related changes: striking increase in clinical stage T1c, systematic use of extended biopsies, and lower percentage of total length of cancer in millimeter in all cores. The MGS used in cohort 2 showed fewer biopsies with Gleason score ≤ 6 and more biopsies of the intermediate Gleason score 7. Time to BR using the Kaplan-Meier curves showed statistical significance using the MGS in cohort 2, but not the SGS in cohort 1. Only the MGS predicted shorter time to BR on univariate analysis and on multivariate analysis was an independent predictor. The results favor that the 2005 International Society of Urological Pathology modified system is a refinement of the Gleason grading and valuable for contemporary clinical practice.

The Applicability Of Ordered Mesoporous Sba-15 And Its Hydrophobic Glutaraldehyde-bridge Derivative To Improve Ibuprofen-loading In Releasing System.

The mesoporous SBA-15 silica with uniform hexagonal pore, narrow pore size distribution and tuneable pore diameter was organofunctionalized with glutaraldehyde-bridged silylating agent. The precursor and its derivative silicas were ibuprofen-loaded for controlled delivery in simulated biological fluids. The synthesized silicas were characterized by elemental analysis, infrared spectroscopy, (13)C and (29)Si solid state NMR spectroscopy, nitrogen adsorption, X-ray diffractometry, thermogravimetry and scanning electron microscopy. Surface functionalization with amine containing bridged hydrophobic structure resulted in significantly decreased surface area from 802.4 to 63.0 m(2) g(-1) and pore diameter 8.0-6.0 nm, which ultimately increased the drug-loading capacity from 18.0% up to 28.3% and a very slow release rate of ibuprofen over the period of 72.5h. The in vitro drug release demonstrated that SBA-15 presented the fastest release from 25% to 27% and SBA-15GA gave near 10% of drug release in all fluids during 72.5 h. The Korsmeyer-Peppas model better fits the release data with the Fickian diffusion mechanism and zero order kinetics for synthesized mesoporous silicas. Both pore sizes and hydrophobicity influenced the rate of the release process, indicating that the chemically modified silica can be suggested to design formulation of slow and constant release over a defined period, to avoid repeated administration.