Separation and detection of narcotic drugs on a microchip using micellar electrokinetic chromatography and electrochemiluminescence

A new approach for fast and sensitive electrochemiluminescence (ECL) detection of narcotic drugs on a microchip after separation by micellar electrokinetic chromatography (MEKC) is presented, taking the cocaine and its hydrolysate ecgonine as the test analytes. The mixture of hydrophilic BMIMBF4 ionic liquid (IL) and sodium dodecyl sulfate (SDS) was used directly as the buffer of MEKC with less noisy baselines, lower electrophoretic current and satisfactory separation performance.

Studies on electrospray mass spectrometry of some narcotic drugs

Using electrospray ionization (ESI) and tandem mass spectrometry techniques, the protonic positions in protonated molecular ions of some narcotic drugs were studied, The data of ESI/MSn experiments of morphine and deuterium-loaded morphine were first discussed. The protonic position was considered to locate on oxygen atom of cyclic ether in morphine molecular, Compared with the same and different: ions among morphine, codeine, acetylcodeine and dihydrocodeine, the protonic positions in protonated molecular ions of these compounds were further determined. The fragmentation mechanism of morphine in ESI/MSn: experiments was also repored in the paper, and there were similar dehydrolysis mechanism in gas phase or in liquid phase for morphine.

The causes of illegal drug industry growth in the Andes, Anti-Drug Policies and their effectiveness

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Análisis de la política anti-narcóticos en la República del Perú y la influencia de la cooperación estadounidense (2006-2011)

En este estudio de caso se presenta un repaso histórico de las políticas anti-narcóticos en el Perú así como la influencia que ha ejercido EE. UU en ésta a través de la cooperación bilateral. Se analizan igualmente los programas de cooperación en el gobierno de Alan García(2006 - 2011) y sus resultados

A cooperação institucional na prevenção do consumo/tráfico juvenil de estupefacientes : Zona de ação do Destacamento Territorial de Sintra

A presente investigação visa aferir formas de cooperação institucional entre o Destacamento Territorial de Sintra e os atores locais na prevenção do consumo/tráfico juvenil de estupefacientes. Pretende-se verificar que ações são desenvolvidas para prevenir este comportamento desviante; que vulnerabilidades são identificadas ao nível da cooperação institucional e melhorias para colmatar essas mesmas vulnerabilidades; e ainda propor possíveis ações ou medidas a serem realizadas, no âmbito da cooperação institucional, na prevenção do consumo/tráfico de estupefacientes. Neste sentido, a Guarda Nacional Republicana, enquanto força de segurança, tem incumbências na prevenção destes comportamentos e na criação de laços cooperativos com outros atores, para que este tipo de ações contribua para a promoção do sentimento de segurança. Além do patrulhamento que os militares efetuam diariamente, os militares das secções de programas especiais do Destacamento Territorial são os que mais lidam com esta problemática, essencialmente na prevenção desenvolvida junto da comunidade escolar. O presente estudo adota uma metodologia de tipo qualitativo. Combina a análise documental sobre a atividade policial do Destacamento Territorial de Sintra com as entrevistas realizadas a militares com funções de chefia e a entidades externas que atuam na zona de ação da subunidade. Os resultados decorrentes das entrevistas revelam sintonia no balanço da cooperação institucional, que tanto a Guarda Nacional Republicana como os atores locais consideram ser positiva. As ações de sensibilização junto dos jovens contam-se entre as atividades realizadas conjuntamente, mas a cooperação também proporciona a partilha de informação que permite agir mais rapidamente. Entre as potencialidades desta cooperação elencadas pelos entrevistados salientou-se assim a experiência adquirida e a facilitação das relações entre instituições, que desbloqueia situações e permite resolver problemas de forma mais célere. No âmbito das potencialidades referiu-se ainda o duplo papel da Guarda Nacional Republicana, que por atuar na prevenção e na aplicação da lei causa mais impacto junto dos jovens. No que diz respeito às vulnerabilidades da cooperação existente, foram apontadas limitações quanto aos recursos humanos e materiais e foi salientada a ausência de uma política de prevenção nas escolas. Mencionaram-se ainda algumas dificuldades pontuais de articulação entre entidades, o que também ocorre por via da falta de interoperabilidade entre sistemas de informação. Por último, no que concerne a recomendações de ações a desenvolver apurou-se a necessidade de reforçar a formação específica no sentido de qualificar um leque mais abrangente de intervenientes; considerou-se pertinente a celebração de contratos locais de segurança; e a especialização dos militares da Guarda Nacional Republicana para se dedicarem unicamente a este tipo de temas. Em suma, a prevenção do consumo/tráfico juvenil de estupefacientes passa, cada vez mais, pela cooperação institucional entre atores, visto que é desta forma que se consegue alcançar um maior número de indivíduos e pelo facto de esta realidade ser um problema socialmente relevante na estruturação social, pelo que reclama esforços e ações conjuntas.

A study of international control of narcotics and dangerous drugs

"Final report, BNDD contract no. 71-28."

Dangerous drugs act, 1932. [22 Geo. 5. Ch. 15.]

Contains amendments to the Dangerous drugs act, 1920-1925.

Regulation of trade in drugs: hearings, Ninety-first Congress, second session, on S. 1575, to regulate trade in drugs and devices by prohibiting the dispensing of drugs or devices by medical practitioners and their participation in profits from the dispensing of such products, except under certain circumstances, and for other purposes, June 16 and 17, 1970.

"Serial no. 91-81."

The Development of an Optimized System of Narcotic and Explosive Contraband Mimics for Calibration and Training of Biological Detectors

Current commercially available mimics contain varying amounts of either the actual explosive/drug or the chemical compound of suspected interest by biological detectors. As a result, there is significant interest in determining the dominant chemical odor signatures of the mimics, often referred to as pseudos, particularly when compared to the genuine contraband material. This dissertation discusses results obtained from the analysis of drug and explosive headspace related to the odor profiles as recognized by trained detection canines. Analysis was performed through the use of headspace solid phase microextraction in conjunction with gas chromatography mass spectrometry (HS-SPME-GC-MS). Upon determination of specific odors, field trials were held using a combination of the target odors with COMPS. Piperonal was shown to be a dominant odor compound in the headspace of some ecstasy samples and a recognizable odor mimic by trained detection canines. It was also shown that detection canines could be imprinted on piperonal COMPS and correctly identify ecstasy samples at a threshold level of approximately 100ng/s. Isosafrole and/or MDP-2-POH show potential as training aid mimics for non-piperonal based MDMA. Acetic acid was shown to be dominant in the headspace of heroin samples and verified as a dominant odor in commercial vinegar samples; however, no common, secondary compound was detected in the headspace of either. Because of the similarities detected within respective explosive classes, several compounds were chosen for explosive mimics. A single based smokeless powder with a detectable level of 2,4-dinitrotoluene, a double based smokeless powder with a detectable level of nitroglycerine, 2-ethyl-1-hexanol, DMNB, ethyl centralite and diphenylamine were shown to be accurate mimics for TNT-based explosives, NG-based explosives, plastic explosives, tagged explosives, and smokeless powders, respectively. The combination of these six odors represents a comprehensive explosive odor kit with positive results for imprint on detection canines. As a proof of concept, the chemical compound PFTBA showed promise as a possible universal, non-target odor compound for comparison and calibration of detection canines and instrumentation. In a comparison study of shape versus vibration odor theory, the detection of d-methyl benzoate and methyl benzoate was explored using canine detectors. While results did not overwhelmingly substantiate either theory, shape odor theory provides a better explanation of the canine and human subject responses.

Screening for drugs in oral fluid : illicit drug use and drug driving in a sample of urban and regional Queensland motorists

Police services in a number of Australian states and overseas jurisdictions have begun to implement or consider random road-side drug testing of drivers. This paper outlines research conducted to provide an estimate of the extent of drug driving in a sample of Queensland drivers in regional, rural and metropolitan areas. Oral fluid samples were collected from 2657 Queensland motorists and screened for illicit substances including cannabis (delta 9 tetrahydrocannibinol [THC]), amphetamines, ecstasy, and cocaine. Overall, 3.8% of the sample (n = 101) screened positive for at least one illicit substance, although multiple drugs were identified in a sample of 23 respondents. The most common drugs detected in oral fluid were ecstasy (n = 53), and cannabis (n = 46) followed by amphetamines (n = 23). A key finding was that cannabis was confirmed as the most common self-reported drug combined with driving and that individuals who tested positive to any drug through oral fluid analysis were also more likely to report the highest frequency of drug driving. Furthermore, a comparison between drug vs. drink driving detection rates for one region of the study, revealed a higher detection rate for drug driving (3.8%) vs. drink driving (0.8%). This research provides evidence that drug driving is relatively prevalent on Queensland roads, and may in fact be more common than drink driving. This paper will further outline the study findings’ and present possible directions for future drug driving research.

Alcohol and other drugs in the Australian construction industry : A national evaluation and the best way forward

Anecdotal evidence highlights issues of alcohol and other drugs (AODs) and its association with safety risk on construction sites. Information is limited however regarding the prevalence of AODs in the workplace and there is limited evidential guidance regarding how to effectively address it. This research aimed to scientifically evaluate the use of AODs within the Australian construction industry in order to reduce the potential resulting safety and performance impacts and engender a cultural change in the workforce. A national qualitative and quantitative evaluation of the use of AODs was conducted with approximately 500 employees. Results indicate that as in the general population, a proportion of those sampled in the construction sector may be at risk of hazardous alcohol consumption and support the need for evidence-based, tailored responses. This is the first known study to scientifically evaluate the use of AODs and potential workplace safety impacts in the construction sector.