Ontario Medical Association fonds, 1972-1973, 1977-1978, 1980-1982, 1984-1985

This archive contains materials relating to the Ontario Medical Association. The bulk of the materials are correspondence. A complete administrative history of the association is available from, The first 100 years : a history of the Ontario Medical Association / Glenn Sawyer, Toronto : The Association, 1980? (R15 O58 S39 1980).

Variability between laboratories performing coagulation tests with identical platforms: a nationwide evaluation study.

BACKGROUND While the assessment of analytical precision within medical laboratories has received much attention in scientific enquiry, the degree of as well as the sources causing variation between them remains incompletely understood. In this study, we quantified the variance components when performing coagulation tests with identical analytical platforms in different laboratories and computed intraclass correlations coefficients (ICC) for each coagulation test. METHODS Data from eight laboratories measuring fibrinogen twice in twenty healthy subjects with one out of 3 different platforms and single measurements of prothrombin time (PT), and coagulation factors II, V, VII, VIII, IX, X, XI and XIII were analysed. By platform, the variance components of (i) the subjects, (ii) the laboratory and the technician and (iii) the total variance were obtained for fibrinogen as well as (i) and (iii) for the remaining factors using ANOVA. RESULTS The variability for fibrinogen measurements within a laboratory ranged from 0.02 to 0.04, the variability between laboratories ranged from 0.006 to 0.097. The ICC for fibrinogen ranged from 0.37 to 0.66 and from 0.19 to 0.80 for PT between the platforms. For the remaining factors the ICC's ranged from 0.04 (FII) to 0.93 (FVIII). CONCLUSIONS Variance components that could be attributed to technicians or laboratory procedures were substantial, led to disappointingly low intraclass correlation coefficients for several factors and were pronounced for some of the platforms. Our findings call for sustained efforts to raise the level of standardization of structures and procedures involved in the quantification of coagulation factors.

Medical Division research report for...

Includes bibliographical references.

1978 Annual Report of the Iowa Board of Medical Examiners, January 29, 1979

This report is submitted in compliance with Senate File 312, section 4, paragraph 2. The Board of Medical Examiners filed their rules relating to the duties of the board on November 19, 1978. These rules were modified as a result of suggestions offered by the Administrative Rules Review Committee and will become effective March 29, 1979

1979 Annual Report of the Iowa Board of Medical Examiners, January 16, 1980

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1980 Annual Report of the Iowa Board of Medical Examiners, January 1, 1981

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1981 Annual Report of the Iowa Board of Medical Examiners, January 29, 1982

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1982 Annual Report of the Iowa Board of Medical Examiners, January 10, 1983

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1983 Annual Report of the Iowa Board of Medical Examiners, January 6, 1984

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1984 Annual Report of the Iowa Board of Medical Examiners, January 30, 1985

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1985 Annual Report of the Iowa Board of Medical Examiners, January 30, 1986

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1986 Annual Report of the Iowa Board of Medical Examiners, January 30, 1987

This report is submitted in compliance with 258A.4(2)of the Code of Iowa.

1987 Annual Report of the Iowa Board of Medical Examiners, January 28, 1988

The Iowa State Board of Medical Examiners submits the following annual report pursuant to the provisions of section 258A.4(2)of the Code of Iowa. the report relates to Board activities during the calendar year.

1988 Annual Report of the Iowa Board of Medical Examiners, January 30, 1989

The Iowa State Board of Medical Examiners submits the following annual report pursuant to the provisions of section 258A.4(2)of the Code of Iowa. The report relates to Board activities during the calendar year.