941 resultados para McDowell, John, 1780-1863.


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"This action ... is brought for two publications in the Evening journal, in the month of February, 1835 ... The declaration sets forth that the defendant meant to charge that impure, dirty and filthy water ... had, for years, been carted to the malt-house of the plaintill; ant that he had been guilty of using that water in preparing barley for malt."--p. 45.

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Plant disease resistance (R) genes confer race-specific resistance to pathogens and are genetically defined on the basis of intra-specific functional polymorphism. Little is known about the evolutionary mechanisms that generate this polymorphism. Most R loci examined to date contain alternate alleles and/or linked homologs even in disease-susceptible plant genotypes. In contrast, the resistance to Pseudomonas syringae pathovar maculicola (RPM1) bacterial resistance gene is completely absent (rpm1-null) in 5/5 Arabidopsis thaliana accessions that lack RPM1 function. The rpm1-null locus contains a 98-bp segment of unknown origin in place of the RPM1 gene. We undertook comparative mapping of RPM1 and flanking genes in Brassica napus to determine the ancestral state of the RPM1 locus. We cloned two B. napus RPM1 homologs encoding hypothetical proteins with ≈81% amino acid identity to Arabidopsis RPM1. Collinearity of genes flanking RPM1 is conserved between B. napus and Arabidopsis. Surprisingly, we found four additional B. napus loci in which the flanking marker synteny is maintained but RPM1 is absent. These B. napus rpm1-null loci have no detectable nucleotide similarity to the Arabidopsis rpm1-null allele. We conclude that RPM1 evolved before the divergence of the Brassicaceae and has been deleted independently in the Brassica and Arabidopsis lineages. These results suggest that functional polymorphism at R gene loci can arise from gene deletions.

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"The first six volumes of this work recorded the progress of Surgery down to 1913. Then came the Great War ... Hence, immediately after the Armistice ... I began to assemble a full staff of experts, whose work appears in Volumes VII and VIII."--Preface, v.7, 1921.

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Includes index.

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Title page includes illustration of a pavement under a columned archway; all other ill. are squares with individual black & white geometric designs, except for leaf [9] which contains squares without designs but with guidelines drawn in them.

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"November 1964."

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Vol. 3 has imprint: Boston, U. S. A., and London.

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Mode of access: Internet.

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