MC1R-dependent, melanin-based colour polymorphism is associated with cell-mediated response in the Eleonora's falcon.

Colour polymorphism in vertebrates is usually under genetic control and may be associated with variation in physiological traits. The melanocortin 1 receptor (Mc1r) has been involved repeatedly in melanin-based pigmentation but it was thought to have few other physiological effects. However, recent pharmacological studies suggest that MC1R could regulate the aspects of immunity. We investigated whether variation at Mc1r underpins plumage colouration in the Eleonora's falcon. We also examined whether nestlings of the different morphs differed in their inflammatory response induced by phytohemagglutinin (PHA). Variation in colouration was due to a deletion of four amino acids at the Mc1r gene. Cellular immune response was morph specific. In males, but not in females, dark nestling mounted a lower PHA response than pale ones. Although correlative, our results raise the neglected possibility that MC1R has pleiotropic effects, suggesting a potential role of immune capacity and pathogen pressure on the maintenance of colour polymorphism in this species.

Cómo exportar a los Estados Unidos caso: una pequeña empresa elaboradora de tortillas de trigo por Eleonora Janette de la Rosa Brandi

Tesis (Maestría en Contaduría Pública con Especialidad en Finanzas) U.A.N.L.

Da. Leonor de Sarabia - Doa Eleonora di Sarabia

UANL

Crönungs-Handlung : Eygendliche Abbild- vnd Erklärung, welcher gestalt die AllerDurchleuchtigste, Großmächtigste Fürstin vnd Fraw, Fraw Eleonora, Röm. Käyserin, in Germanien, zu Hungarn vnnd Böheim Königin ... den 7. Novemb. ... deß 1630. Jahres, bey endung deß Churfürstlichen Collegial-Tags, in Regenspurg zur Römischen Käyserin solenniter gekrönet worden

Abgezeichnet, in Kupffer gebracht vnd zu finden bey Johann Hauer Mahlern vnd Kunsthändlern in Nürnberg

Eleonora Duse, Szenenfoto, Kniestück

Signatur des Originals: S 36/F03502

Eleonora Duse, Rollenbild, Kniestück

Signatur des Originals: S 36/F03503

Eleonora Duse, Rollenbild, Kniestück

Signatur des Originals: S 36/F03505

Eleonora Duse, Rollenbild, Brustbild

Signatur des Originals: S 36/F03506

Eleonora Duse, Rollenbild, Brustbild, in: Alexander Dumas: La Dame aux camélias

Signatur des Originals: S 36/F03507

Eleonora Duse, Rollenbild, Brustbild

Signatur des Originals: S 36/F03508

Eleonora Duse als Cleopatra, Szenenfoto, in: William Shakespeare: Antonius und Cleopatra

Signatur des Originals: S 36/F08492

Eleonora Duse, Brustbild, Profil

Signatur des Originals: S 36/F08493