Niagara Lodges of the Loyal Orange Association of British America

The Loyal Orange Association of British America is a Protestant fraternal society. The Loyal Orange Association originated in Ulster, Ireland during the late eighteenth century. Its purpose was to promote Protestant rights and privileges. The association was exclusively Protestant, fraternal, democratic, and benevolent. Orange principles were brought to Upper Canada by Protestant Irish settlers after 1815. The first Canadian Orange Lodge was formally established in Brockville, Leeds County, 1830. By the late 19th and early 20th century, the Loyal Orange Association of British North America had gained considerable popularity and political influence. Many prominent politicians, including several prime ministers, were members. Orangemen were particularly concerned with issues such as separate school funding, language rights, immigration, religious freedom and conscription. Further, they demanded the execution of Louis Riel and opposed the Jesuits Estates settlement. Administrative sketch courtesy Archives of Ontario.

Historial and descriptive sketches of the maritime colonies of British America.

Account of Prince Edward Island--Account of Cape Breton--Sketches of Nova Scotia--New Brunswick--Newfoundland.

Reports of the Parliamentary Committee of the Loyal Repeal Association of Ireland.

Mode of access: Internet.

The backwoods of Canada : being letters from the wife of an emigrant officer, illustrative of the domestic economy of British America.

Mode of access: Internet.

Fauna boreali-americana, or, The zoology of the northern parts of British America : containing descriptions of the objects of natural history collected on the late northern land expedition, under command of Captain Sir John Franklin, R.N. /

"Illustrated by numerous plates."

A summary view of the rights of British America : set forth in some resolutions intended for the inspection of the present delegates of the people of Virginia, now in convention... /

Dedication "to the King" signed: Tribunus. [pseud. of Arthur Lee].

The backwoods of Canada: being letters from the wife of an emigrant officer, illustrative of the domestic economy of British America.

With : The Oregon territory / Charles Grenfell Nicolay. London : Knight, 1846.

Flora boreali-Americana, or, The botany of the Northern parts of British America ....

Mode of access: Internet.

Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population

Objective: Association between ankylosing spondylitis (AS) and two genes, ERAP1 and IL23R, has recently been reported in North American and British populations. The population attributable risk fraction for ERAP1 in this study was 25%, and for IL23R, 9%. Confirmation of these findings to ERAP1 in other ethnic groups has not yet been demonstrated. We sought to test the association between single nucleotide polymorphisms (SNPs) in these genes and susceptibility to AS among a Portuguese population. We also investigated the role of these genes in clinical manifestations of AS, including age of symptom onset, the Bath Ankylosing Spondylitis Disease Activity, Metrology and Functional Indices, and the modified Stoke Ankylosing Spondylitis Spinal Score. Methods: The study was conducted on 358 AS cases and 285 ethnically matched Portuguese healthy controls. AS was defined according to the modified New York Criteria. Genotyping of IL23R and ERAP1 allelic variants was carried out with TaqMan allelic discrimination assays. Association analysis was performed using the Cochrane-Armitage and linear regression tests of genotypes as implemented in PLINK for dichotomous and quantitative variables respectively. A meta-analysis for Portuguese and previously published Spanish IL23R data was performed using the StatsDirect® Statistical tools, by fixed and random effects models. Results: A total of 14 nsSNPs markers (8 for IL23R, 5 for ERAPl, 1 for LN-PEP) were analysed. Three markers (2 for IL23R and 1 for ERAP1) showed significant single-locus disease associations, confirming that the association of these genes with AS in the Portuguese population. The strongest associated SNP in IL23R was rs1004819 (OR=1.4, p=0.0049), and in ERAP1 was rs30187 (OR=1.26, p=0.035). The population attributable risk fractions in the Portuguese population for these SNPs are 11% and 9.7% respectively. No association was seen with any SNP in LN-PEP, which flanks ERAP1 and was associated with AS in the British population. No association was seen with clinical manifestations of AS. Conclusions: These results show that IL23R and ERAP1 genes are also associated with susceptibility to AS in the Portuguese population, and that they contribute a significant proportion of the population risk for this disease.

Proceedings of the first annual session of the Southern immigration association of America, held at Nashville, Tenn., March 11, 12 and 13, 1884.

Mode of access: Internet.

In re mediation proceedings between division 268 of the Amalgamated Association of Street and Electric Railway Employes of America and the Cleveland Railway Company. Statement of the Cleveland Railway Company. June, 1918. Squire, Sanders & Dempsey, general counsel.

Mode of access: Internet.