The Geology of Lost Creek Canyon with Special Reference to Igneous Activity

This investigation was undertaken primarily as a problem in geologic mapping, coupled with a study of stratigraphy, glaciation, igneous phenomena, and structure. The area is admirably suited to a study of geology and geologic events. Because it is small in extent, the area was studied in some detail during the time which was devoted to field work. The record of igneous activity of past geological ages is re­markably well exposed, since Lost Creek Canyon was carved through the roof of a stock or batholith by the glaciers of the Pleistocene epoch.

Geology of the Lost Creek-Modesty Creek Area Deerlodge County, Montana

In 1915 the United States Geological Survey published a folio by Calkins and Emmons on the geology of the Philipsburg Quadrangle, which ad­joins the area now under study to the west. Geology of this portion of Montana had not been mapped previously; consequently the purpose of this thesis is to make a geological reconnais­sance of the stratigraphy and structure of the area.

06015-008 Bear Creek Watershed Final Report

Big Bear Creek is the upper portion of Bear Creek which drains 26,734 acres and ends at the Highway 136 crossing of Bear Creek. Bear Creek flows into the section of the Maquoketa River, which is on the EPA’s 303(d) List of Impaired Waters. Monitoring by the Iowa DNR indicates that Bear Creek is contributing significant amounts of sediment and nutrients to the Maquoketa River. The primary use of land in the Big Bear Creek Watershed is row crop production. A roadside survey completed by Anamosa Field Office Staff indicated that 123,747 tons/yr. of sediment was being lost due to sheet and rill erosion only. The sediment delivered to Big Bear Creek is 24,447 tons/yr. Based on this data, 34,226 lbs. of Phosphorus is reaching the stream per year. With the added amount of sediment and phosphorus delivery through gully and streambank erosion, one can clearly see that the water quality in Bear Creek is severely impaired. The Big Bear Watershed Project will work to reduce the sediment and phosphorus delivered to the stream by 30% through the installation of practices that trap sediment and reduce erosion.

Charles Wm. Post at his desk, Battle Creek office, Postum Cereal, ca. 1912

this is a black and white copy of a lost /unlocated original. COPY print by James R. Dunlop, Washington, DC

Permian stratigraphy of the Woolaga creek area, Mingenew District, Western Australia

Six units are distinguished in the Permian sequence, and are considered to belong to the Sakmarian and Artinskian stages.

Proteomic analysis of normal and malignant prostate tissue to identify novel proteins lost in cancer

BACKGROUND. Alterations of important protein pathways, including loss of prostate secretory granules, and disruption of the prostatic secretory pathway have been identified as early events in malignancy. In this study, proteomics was used to map the differences in protein expression between normal and malignant prostate tissues and to identify and analyze differentially expressed proteins in human prostate tissue with particular regard to the proteins lost in malignancy. METHODS. Small quantities of normal and malignant prostate tissue were taken fresh from 34 radical prostatectomy cases. After histological examination, proteins were solubilized from selected tissues and separated using two-dimensional electrophoresis. Using image analysis, the proteome of normal and malignant tissues were mapped and differentially expressed proteins (present in normal and absent in malignant tissue) were identified and subsequently analyzed using peptide mass finger printing and N-terminal sequencing. Western blotting and immunohistochemistry were performed to examine expression profiles and tissue localization of candidate proteins. RESULTS. Comparison of protein maps of normal and malignant prostate were used to identify 20 proteins which were lost in malignant transformation, including prostate specific antigen (PSA), alpha-l antichymotrypsin (ACT), haptoglobin, and lactoylglutathione lyase. Three of the 20 had not previously been reported in human prostate tissue (Ubiquitin-like NEDD8, calponin, and a follistatin-related protein). Western blotting confirmed differences in the expression profiles of NEDD8 and calponin, and immunohistochemistry demonstrated differences in the cellular localization of these two proteins in normal and malignant prostate glands. CONCLUSIONS. The expression of NEDD8, calponin, and the follistatin-related protein in normal prostate tissues is a novel finding and the role of these important functional proteins in normal prostate and their loss or reduced expression in prostate malignancy warrants further investigations. (C) 2002 Wiley-Liss, Inc.