Tensiones y desajustes en los roles actanciales en torno al episodio del asesinato de Lope Díaz de haro según la versión de la Crónica de Sancho IV

Las tensiones políticas que signaron el reinado de Sancho IV (1284-1295) llegan a un punto de inflexión en la entrevista que en 1288 se lleva a cabo en Alfaro, en la cual resulta asesinado el principal enemigo del rey, el conde Lope Díaz de Haro. El episodio se recoge tanto en la Crónica de tres reyes como en la sección conocida como *Historia hasta 1288 dialogada, transmitida en la Estoria del fecho de los godos . La orientación que al hecho se le asigna en ambas versiones es diversa ?entre otras cosas? en el grado de responsabilidad que se le asigna al rey en la decisión de matar al conde. La Crónica de tres reyes tiende a mitigar la injerencia del monarca en los hechos al punto de organizar una serie de situaciones previas que generan las condiciones necesarias para que el asesinato se presente como un hecho inevitable que excede el radio de acción de Sancho.

Tensiones y desajustes en los roles actanciales en torno al episodio del asesinato de Lope Díaz de haro según la versión de la Crónica de Sancho IV

Las tensiones políticas que signaron el reinado de Sancho IV (1284-1295) llegan a un punto de inflexión en la entrevista que en 1288 se lleva a cabo en Alfaro, en la cual resulta asesinado el principal enemigo del rey, el conde Lope Díaz de Haro. El episodio se recoge tanto en la Crónica de tres reyes como en la sección conocida como *Historia hasta 1288 dialogada, transmitida en la Estoria del fecho de los godos . La orientación que al hecho se le asigna en ambas versiones es diversa ?entre otras cosas? en el grado de responsabilidad que se le asigna al rey en la decisión de matar al conde. La Crónica de tres reyes tiende a mitigar la injerencia del monarca en los hechos al punto de organizar una serie de situaciones previas que generan las condiciones necesarias para que el asesinato se presente como un hecho inevitable que excede el radio de acción de Sancho.

Tensiones y desajustes en los roles actanciales en torno al episodio del asesinato de Lope Díaz de haro según la versión de la Crónica de Sancho IV

Las tensiones políticas que signaron el reinado de Sancho IV (1284-1295) llegan a un punto de inflexión en la entrevista que en 1288 se lleva a cabo en Alfaro, en la cual resulta asesinado el principal enemigo del rey, el conde Lope Díaz de Haro. El episodio se recoge tanto en la Crónica de tres reyes como en la sección conocida como *Historia hasta 1288 dialogada, transmitida en la Estoria del fecho de los godos . La orientación que al hecho se le asigna en ambas versiones es diversa ?entre otras cosas? en el grado de responsabilidad que se le asigna al rey en la decisión de matar al conde. La Crónica de tres reyes tiende a mitigar la injerencia del monarca en los hechos al punto de organizar una serie de situaciones previas que generan las condiciones necesarias para que el asesinato se presente como un hecho inevitable que excede el radio de acción de Sancho.

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010 : a systematic analysis for the Global Burden of Disease Study 2010

Background Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. The Global Burden of Disease (GBD) studies done in 1990 and 2000 have been the only studies to quantify non-fatal health outcomes across an exhaustive set of disorders at the global and regional level. Neither effort quantified uncertainty in prevalence or years lived with disability (YLDs). Methods Of the 291 diseases and injuries in the GBD cause list, 289 cause disability. For 1160 sequelae of the 289 diseases and injuries, we undertook a systematic analysis of prevalence, incidence, remission, duration, and excess mortality. Sources included published studies, case notification, population-based cancer registries, other disease registries, antenatal clinic serosurveillance, hospital discharge data, ambulatory care data, household surveys, other surveys, and cohort studies. For most sequelae, we used a Bayesian meta-regression method, DisMod-MR, designed to address key limitations in descriptive epidemiological data, including missing data, inconsistency, and large methodological variation between data sources. For some disorders, we used natural history models, geospatial models, back-calculation models (models calculating incidence from population mortality rates and case fatality), or registration completeness models (models adjusting for incomplete registration with health-system access and other covariates). Disability weights for 220 unique health states were used to capture the severity of health loss. YLDs by cause at age, sex, country, and year levels were adjusted for comorbidity with simulation methods. We included uncertainty estimates at all stages of the analysis. Findings Global prevalence for all ages combined in 2010 across the 1160 sequelae ranged from fewer than one case per 1 million people to 350 000 cases per 1 million people. Prevalence and severity of health loss were weakly correlated (correlation coefficient −0·37). In 2010, there were 777 million YLDs from all causes, up from 583 million in 1990. The main contributors to global YLDs were mental and behavioural disorders, musculoskeletal disorders, and diabetes or endocrine diseases. The leading specific causes of YLDs were much the same in 2010 as they were in 1990: low back pain, major depressive disorder, iron-deficiency anaemia, neck pain, chronic obstructive pulmonary disease, anxiety disorders, migraine, diabetes, and falls. Age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010. Regional patterns of the leading causes of YLDs were more similar compared with years of life lost due to premature mortality. Neglected tropical diseases, HIV/AIDS, tuberculosis, malaria, and anaemia were important causes of YLDs in sub-Saharan Africa. Interpretation Rates of YLDs per 100 000 people have remained largely constant over time but rise steadily with age. Population growth and ageing have increased YLD numbers and crude rates over the past two decades. Prevalences of the most common causes of YLDs, such as mental and behavioural disorders and musculoskeletal disorders, have not decreased. Health systems will need to address the needs of the rising numbers of individuals with a range of disorders that largely cause disability but not mortality. Quantification of the burden of non-fatal health outcomes will be crucial to understand how well health systems are responding to these challenges. Effective and affordable strategies to deal with this rising burden are an urgent priority for health systems in most parts of the world. Funding Bill & Melinda Gates Foundation.

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: Quantifying the epidemiological transition

Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. Methods We used the published GBD 2013 data for age-specific mortality, years of life lost due to premature mortality (YLLs), and years lived with disability (YLDs) to calculate DALYs and HALE for 1990, 1995, 2000, 2005, 2010, and 2013 for 188 countries. We calculated HALE using the Sullivan method; 95% uncertainty intervals (UIs) represent uncertainty in age-specific death rates and YLDs per person for each country, age, sex, and year. We estimated DALYs for 306 causes for each country as the sum of YLLs and YLDs; 95% UIs represent uncertainty in YLL and YLD rates. We quantified patterns of the epidemiological transition with a composite indicator of sociodemographic status, which we constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population. We applied hierarchical regression to DALY rates by cause across countries to decompose variance related to the sociodemographic status variable, country, and time. Findings Worldwide, from 1990 to 2013, life expectancy at birth rose by 6·2 years (95% UI 5·6–6·6), from 65·3 years (65·0–65·6) in 1990 to 71·5 years (71·0–71·9) in 2013, HALE at birth rose by 5·4 years (4·9–5·8), from 56·9 years (54·5–59·1) to 62·3 years (59·7–64·8), total DALYs fell by 3·6% (0·3–7·4), and age-standardised DALY rates per 100 000 people fell by 26·7% (24·6–29·1). For communicable, maternal, neonatal, and nutritional disorders, global DALY numbers, crude rates, and age-standardised rates have all declined between 1990 and 2013, whereas for non–communicable diseases, global DALYs have been increasing, DALY rates have remained nearly constant, and age-standardised DALY rates declined during the same period. From 2005 to 2013, the number of DALYs increased for most specific non-communicable diseases, including cardiovascular diseases and neoplasms, in addition to dengue, food-borne trematodes, and leishmaniasis; DALYs decreased for nearly all other causes. By 2013, the five leading causes of DALYs were ischaemic heart disease, lower respiratory infections, cerebrovascular disease, low back and neck pain, and road injuries. Sociodemographic status explained more than 50% of the variance between countries and over time for diarrhoea, lower respiratory infections, and other common infectious diseases; maternal disorders; neonatal disorders; nutritional deficiencies; other communicable, maternal, neonatal, and nutritional diseases; musculoskeletal disorders; and other non-communicable diseases. However, sociodemographic status explained less than 10% of the variance in DALY rates for cardiovascular diseases; chronic respiratory diseases; cirrhosis; diabetes, urogenital, blood, and endocrine diseases; unintentional injuries; and self-harm and interpersonal violence. Predictably, increased sociodemographic status was associated with a shift in burden from YLLs to YLDs, driven by declines in YLLs and increases in YLDs from musculoskeletal disorders, neurological disorders, and mental and substance use disorders. In most country-specific estimates, the increase in life expectancy was greater than that in HALE. Leading causes of DALYs are highly variable across countries. Interpretation Global health is improving. Population growth and ageing have driven up numbers of DALYs, but crude rates have remained relatively constant, showing that progress in health does not mean fewer demands on health systems. The notion of an epidemiological transition—in which increasing sociodemographic status brings structured change in disease burden—is useful, but there is tremendous variation in burden of disease that is not associated with sociodemographic status. This further underscores the need for country-specific assessments of DALYs and HALE to appropriately inform health policy decisions and attendant actions.

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution. Methods Attributable deaths, years of life lost, years lived with disability, and disability-adjusted life-years (DALYs) have been estimated for 79 risks or clusters of risks using the GBD 2010 methods. Risk–outcome pairs meeting explicit evidence criteria were assessed for 188 countries for the period 1990–2013 by age and sex using three inputs: risk exposure, relative risks, and the theoretical minimum risk exposure level (TMREL). Risks are organised into a hierarchy with blocks of behavioural, environmental and occupational, and metabolic risks at the first level of the hierarchy. The next level in the hierarchy includes nine clusters of related risks and two individual risks, with more detail provided at levels 3 and 4 of the hierarchy. Compared with GBD 2010, six new risk factors have been added: handwashing practices, occupational exposure to trichloroethylene, childhood wasting, childhood stunting, unsafe sex, and low glomerular filtration rate. For most risks, data for exposure were synthesised with a Bayesian meta-regression method, DisMod-MR 2.0, or spatial-temporal Gaussian process regression. Relative risks were based on meta-regressions of published cohort and intervention studies. Attributable burden for clusters of risks and all risks combined took into account evidence on the mediation of some risks such as high body-mass index (BMI) through other risks such as high systolic blood pressure and high cholesterol. Findings All risks combined account for 57·2% (95% uncertainty interval [UI] 55·8–58·5) of deaths and 41·6% (40·1–43·0) of DALYs. Risks quantified account for 87·9% (86·5–89·3) of cardiovascular disease DALYs, ranging to a low of 0% for neonatal disorders and neglected tropical diseases and malaria. In terms of global DALYs in 2013, six risks or clusters of risks each caused more than 5% of DALYs: dietary risks accounting for 11·3 million deaths and 241·4 million DALYs, high systolic blood pressure for 10·4 million deaths and 208·1 million DALYs, child and maternal malnutrition for 1·7 million deaths and 176·9 million DALYs, tobacco smoke for 6·1 million deaths and 143·5 million DALYs, air pollution for 5·5 million deaths and 141·5 million DALYs, and high BMI for 4·4 million deaths and 134·0 million DALYs. Risk factor patterns vary across regions and countries and with time. In sub-Saharan Africa, the leading risk factors are child and maternal malnutrition, unsafe sex, and unsafe water, sanitation, and handwashing. In women, in nearly all countries in the Americas, north Africa, and the Middle East, and in many other high-income countries, high BMI is the leading risk factor, with high systolic blood pressure as the leading risk in most of Central and Eastern Europe and south and east Asia. For men, high systolic blood pressure or tobacco use are the leading risks in nearly all high-income countries, in north Africa and the Middle East, Europe, and Asia. For men and women, unsafe sex is the leading risk in a corridor from Kenya to South Africa. Interpretation Behavioural, environmental and occupational, and metabolic risks can explain half of global mortality and more than one-third of global DALYs providing many opportunities for prevention. Of the larger risks, the attributable burden of high BMI has increased in the past 23 years. In view of the prominence of behavioural risk factors, behavioural and social science research on interventions for these risks should be strengthened. Many prevention and primary care policy options are available now to act on key risks.

Aproximación al pintor Epifanio Díaz de Arcaute (1845-1910)

[ES]Con este trabajo pretendemos aproximarnos a la figura de Epifanio Díaz de Arcaute (1845-1910), un pintor no demasiado conocido y con una producción artística, por el momento, escasa. Su formación fue tradicional y académica, vinculada a la Academia de Bellas Artes de Vitoria, de la que terminó siendo profesor.

Cartas enviadas por Leonel Acevedo Díaz a Justo Garate entre 1955 y 1961

5 cartas (mecanografiadas y manuscritas) ; entre 170x220mm y 145x230mm. Ubicación: Caja 1 - Carpeta 3

Plan de marketing para el hotel López de Haro

El objeto del presente Trabajo Fin de Grado (TFG) es realizar un Plan de Marketing para el Hotel López de Haro de 5 estrellas, perteneciente a la cadena Ercilla y ubicado en Bilbao. Para ello, se ha analizado tanto el entorno interno como el externo, detectándose una serie de fortalezas entre las que destaca el excelente trato personal que ofrecen los empleados a sus huéspedes y que es un factor clave sobre el que cimentar su futuro. Asimismo, se han detectado debilidades, oportunidades y amenazas sobre las que hay que trabajar. Con ese diagnóstico y con una orientación al cliente se han definido objetivos de marketing alcanzables y que permitieran, mediante diferentes estrategias y acciones satisfacer las necesidades de la clientela. En este sentido, se han investigado también las tendencias del mercado y, teniendo en cuenta estas y la realidad del hotel, se ha aportado una visión externa que les permita mejorar el funcionamiento del hotel.

Semblanzas Ictiológicas: Juan Martín Díaz de Astarloa

A través de esta serie intentaremos conocer diferentes facetas personales de los integrantes de nuestra “comunidad”. El cuestionario, además de su principal objetivo, con sus respuestas quizás nos ayude a encontrar entre nosotros puntos en común que vayan más allá de nuestros temas de trabajo y sea un aporte a futuros estudios históricos. Esperamos que esta iniciativa pueda ser otro nexo entre los ictiólogos de la región, ya que consideramos que el resultado general trascendería nuestras fronteras.

Ictiólogos de la Argentina: José Gustavo Haro

This series will include all those people who, by means of their contributions, great and small, played a part in the consolidation of ichthyology in Argentina. The general plan of this work consists of individual factsheets containing a list of works by each author, along with reference bibliography and, whenever possible, personal pictures and additional material. The datasheets will be published primarily in chronological order, although this is subject to change by the availability of materials for successive editions. This work represents another approach for the recovery and revalorization of those who set the foundations of Argentine ichthyology while in diverse historical circumstances. I expect this to be the beginning of a major work that achieves the description of such a significant part of the history of natural sciences in Argentina.

'Pues no entiendo tus palabras, / y tus bofetones siento': Linguistic Subversion in Lope de Vega's 'El perro del hortelano'

En los últimos años los críticos han dedicado mucha atención a la investigación de las voces conflictivas de la obra dramática de Lope de Vega. Se ha enfatizado en particular el papel subversivo de la lengua, sobre todo desde la perspectiva de la teoría de los actos de habla. Este artículo sobre El perro del hortelano opera dentro de un marco teórico similar para analizar cómo las retóricas poco estables del honor y del amor conducen a una desintegración de estos códigos artificiales linguísticos. Además, sugieren la presencia de una inestabilidad social colectiva más siniestra y más comprometida fuera del escenario. La ironía dramática, que sostiene el encubrimiento y la revelación de la 'verdad' a lo largo de la obra, lleva a un desenlace más liminal que cerrado y, quizás, permite la recuperación de unas voces significativas que penetren más allá del tiempo y la época en que fue escrita la obra.