The spatial patterns of β/A4 deposit subtypes in Down's syndrome

The spatial patterns of diffuse, primitive and classic β/A4 deposits were studied in coronal sections of the hippocampus and adjacent gyri in 11 cases of Down's syndrome (DS) varying in age from 38 to 67 years. The objectives of the study were first, to compare the spatial patterns of β/A4 deposits revealed in DS with those reported in cases of Alzheimer's disease (AD) and second, to study how the spatial patterns of β/A4 deposits may develop in the tissue. The spatial patterns revealed in DS exhibited a number of similarities with those reported in AD: (1) the range and frequency of the different types of spatial pattern revealed were similar, (2) β/A4 deposits occurred in clusters and in many cortical tissues, the clusters were distributed in a regular pattern parallel to the pia, (3) the clusters of diffuse and primitive β/A4 deposits occurred in an alternating pattern along the cortex, and (4) the clusters of classic β/A4 deposits were not correlated with the clusters of the diffuse and primitive deposits. Primitive deposits may develop from the diffuse deposits in regions of the cortex where extracellular paired helical filaments were formed. However, clusters of the classic β/A4 deposits, which are formed in older cases, appear to develop independently of the diffuse and primitive deposits. © 1994 Springer-Verlag.

Compendio de los cinco tomos de los annales de Navarra / compuesto por el Padre Pablo Miguel de Elizondo...

Sign.: [], *-4*2, A4, C-Z4, 2A-2Z4, 3A-3Z4, 4A-4P4, 4Q-4Z2, 5A-5R2

Vida, virtudes, milagros, y festivos cultos de Santo Thomas de Villanueva Arzobispo de Valencia, de la Orden de N.G.P. San Agustin

Contiene con portadilla propia : Mich. Io. Bodini Panegyricus Beato Thomae archiep. valent. scriptus ..

Obras de la gloriosa Madre Santa Teresa de Jesus, fundadora de la reforma de la Orden de Nuestra Señora del Carmen ... : [tomo II]

Contiene: Prólogo de la Santa Madre Teresa de Jesús : Moradas de Santa Teresa, p. 1-203 -- Exclamaciones o Meditaciones del Alma a su Dios, 204-232 -- Libro de las Fundaciones, p. 233-524 -- Conceptos del Amor de Dios, p. 527-582 -- Siete Meditaciones sobre El Pater Noster, p. 583-612

Cartas de Santa Teresa de Jesus ... fundadora ... de la Orden... del Carmen ...

Indice de las cartas, p. [19] ; Indice de las cosas notables, p. I-XXVIII

Prima pars totius Summe maioris beati Antonini

Sign.: a4, []2, a4, b-z8, r8, [et]8, [rum]8, aa-ff8

Sanctissimi domini nostri Benedicti XIV ... Acta et decreta in causis beatificationum et canonizationum : aliisque ad sacrorum rituum materiam pertinentibus ad annum pontificatus sui decimum

Mode of access: Internet.

Précis sur la nature des maladies produites par le vice des humeurs lymphatiques, leur différentes espèces, et le traitement qui leur convient : avec des observations intéressantes sur la plupart de ces maladies ...; suivi d'une Dissertation sur une grossesse vaginale.

Mode of access: Internet.

A practical essay on diseases of the viscera : particulary those of the stomach and bowels, the liver, spleen and urinaty bladder, in which their nature, treatment and cure, are cleary pointed out and explained /

Mode of access: Internet.

A dissertation on suspended respiration from drowning, hanging and suffocation : in which is recommended a differect mode of treatment to any hitherto pointed out /

Mode of access: Internet.

Observations medical and political on the small-pox and the advantages and disadvantages of general inoculation especially in cities, and on the mortality of mankind at every age in city and country... /

Mode of access: Internet.

Collection académique composée des mémoires, actes ou journaux des plus célébres académies & sociétés littéraires de l'Europe : concernant l'histoire naturelle, la physique expérimentale, la chymie, la botanique, l'anatomie et la médecine ; tome dixieme de la partie étrangere, contenant les Mémories de l'Academie des Sciences de l'Institut de Bologne /

Mode of access: Internet.