945 resultados para Lee, George
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Title on spine: Lee Arches & Prerogative Courts.
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Mode of access: Internet.
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Background: The identification and characterization of genes that influence the risk of common, complex multifactorial disease primarily through interactions with other genes and environmental factors remains a statistical and computational challenge in genetic epidemiology. We have previously introduced a genetic programming optimized neural network (GPNN) as a method for optimizing the architecture of a neural network to improve the identification of gene combinations associated with disease risk. The goal of this study was to evaluate the power of GPNN for identifying high-order gene-gene interactions. We were also interested in applying GPNN to a real data analysis in Parkinson's disease. Results: We show that GPNN has high power to detect even relatively small genetic effects (2-3% heritability) in simulated data models involving two and three locus interactions. The limits of detection were reached under conditions with very small heritability (
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Lee, a Boston merchant who often represented the city as deputy in the Massachusetts General Court, asks Baldwin if the laborers laying the bricks and stone for University Hall could be loaned for a few days to work on the construction of the South meeting house [New South Church].
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At head of title: The Port of New York authority created by compact between the states of New York and New Jersey with the consent of Congress.
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Mode of access: Internet.