The fearsome island, being a modern rendering of the narrative ofone Seld Fordred, master marines of Hythe, whose shipwreck and subsequent adventures are herein set forth...

UANL

Resultados de la cirugía laparoscópica comparada con la cirugía abierta en el cáncer colorrectal. Revisión sistemática

Determinar el efecto de la cirugía laparoscópica versus cirugía abierta sobre la supervivencia en el manejo de pacientes del cáncer colorectal.

Estado nutricional, desarrollo madurativo y sufrimiento mental en niños, niñas y adolescentes de comunidades cercanas al proyecto megaminero “Fruta del Norte” en comparación con comunidades de minería artesanal

El estudio analiza las condiciones nutricionales, desarrollo madurativo y el estado emocional en niños/as y adolescentes (NNA) de comunidades ecuatorianas de minería artesanal; en comparación con NNA de comunidades ubicadas en la zona de influencia del proyecto megaminero "Fruta del Norte", concesionado a la multinacional Kinross Aurelian, actualmente en fase de exploración avanzada.

Host-gut microbiota metabolic interactions

The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the gut, liver, muscle, and brain. A deeper understanding of these axes is a prerequisite for optimizing therapeutic strategies to manipulate the gut microbiota to combat disease and improve health.

Therapeutic modulation of microbiota-host metabolic interactions

The complex metabolic relationships between the host and its microbiota change throughout life and vary extensively between individuals, affecting disease risk factors and therapeutic responses through drug metabolism. Elucidating the biochemical mechanisms underlying this human supraorganism symbiosis is yielding new therapeutic insights to improve human health, treat disease, and potentially modify human disease risk factors. Therapeutic options include targeting drugs to microbial genes or co-regulated host pathways and modifying the gut microbiota through diet, probiotic and prebiotic interventions, bariatric surgery, fecal transplants, or ecological engineering. The age-associated co-development of the host and its microbiota provides a series of windows for therapeutic intervention from early life through old age

Analysis of spring break-up and its effects on a biomass feedstock supply chain in northern Michigan

Demand for bio-fuels is expected to increase, due to rising prices of fossil fuels and concerns over greenhouse gas emissions and energy security. The overall cost of biomass energy generation is primarily related to biomass harvesting activity, transportation, and storage. With a commercial-scale cellulosic ethanol processing facility in Kinross Township of Chippewa County, Michigan about to be built, models including a simulation model and an optimization model have been developed to provide decision support for the facility. Both models track cost, emissions and energy consumption. While the optimization model provides guidance for a long-term strategic plan, the simulation model aims to present detailed output for specified operational scenarios over an annual period. Most importantly, the simulation model considers the uncertainty of spring break-up timing, i.e., seasonal road restrictions. Spring break-up timing is important because it will impact the feasibility of harvesting activity and the time duration of transportation restrictions, which significantly changes the availability of feedstock for the processing facility. This thesis focuses on the statistical model of spring break-up used in the simulation model. Spring break-up timing depends on various factors, including temperature, road conditions and soil type, as well as individual decision making processes at the county level. The spring break-up model, based on the historical spring break-up data from 27 counties over the period of 2002-2010, starts by specifying the probability distribution of a particular county’s spring break-up start day and end day, and then relates the spring break-up timing of the other counties in the harvesting zone to the first county. In order to estimate the dependence relationship between counties, regression analyses, including standard linear regression and reduced major axis regression, are conducted. Using realizations (scenarios) of spring break-up generated by the statistical spring breakup model, the simulation model is able to probabilistically evaluate different harvesting and transportation plans to help the bio-fuel facility select the most effective strategy. For early spring break-up, which usually indicates a longer than average break-up period, more log storage is required, total cost increases, and the probability of plant closure increases. The risk of plant closure may be partially offset through increased use of rail transportation, which is not subject to spring break-up restrictions. However, rail availability and rail yard storage may then become limiting factors in the supply chain. Rail use will impact total cost, energy consumption, system-wide CO2 emissions, and the reliability of providing feedstock to the bio-fuel processing facility.

Davenant,

Mode of access: Internet.

ASSESSMENT OF ASPEN AND NORTHERN HARDWOODS EXTENT IN THIRTY THREE COUNTIES OF UPPER/LOWER MICHIGAN

The importance of the United States' wood and wood byproducts as biomass feedstocks is increasing as the concern about security and sustainability of global energy production continues to rise. Thus, second generation woody feedstock sources in Michigan, e.g., hybrid poplar and hybrid willow (Populus spp.), are viewed as a potential source of biomass for the proposed biofuel ethanol production plant in Kinross, MI. It is important to gain an understanding of the spatial distribution of current feedstock sources, harvesting accessibility via the transportation infrastructure and land ownerships in order to ensure long-term feedstock extent. This research provides insights into the current extent of aspen and northern hardwoods, and an assessment of potential for expanding the area of these feedstock sources based on pre-European settlement conditions. A geographic information system (GIS) was developed to compile available geospatial data for 33 counties located within 150 miles of the Kinross facility. These include present day and pre-European settlement land use/cover, soils, road infrastructure, and land ownerships. The results suggest that a significant amount of northern hardwoods has been converted to other land use/cover types since European settlement, and the "scattering" of aspen stands has increased. Furthermore, a significant amount of woody biomass is available in close proximity to the existing road network, which can be effectively utilized as feedstock. Potential aspen and northern hardwoods restoration areas are identified in the vicinity of road networks which can be used for future woody feedstock production.