Inventarnyĭ katalog kleĭm na amfornykh ruchkakh i gorlyshkakh i na cherepit︠s︡akh ėrmitazhnagʹo sobranīi︠a︡. S Z risunkami v teksti︠e︡, 15 fototipicheskimi i l avtotipicheskoi︠u︡ tablit︠s︡ami.

Romanized record.

Mellastavat pirut : uskomustarinat kognitiivisina ongelmanratkaisumalleina

Elektroninen aineisto

Kokemuksia avainhenkilöihin vaikuttamisesta ISAF- ja UNIFIL -operaatioissa : haasteita, mahdollisuuksia ja onnistumisen edellytyksiä

Tämän tutkimuksen tarkoituksena oli selvittää suomalaisten nuorempien upseerien kokemuksia avainhenkilöihin vaikuttamisesta kriisinhallintaoperaatiossa. Näkökulmana teorian osalta käytettiin viestinnän lineaarista prosessimallia. Tutkimuskohteen osalta keskityttiin avainhenkilöihin vaikuttamiseen taktisella tasolla, tarkemmin ottaen joukkue- ja komppaniatasolla. Kokemuksissa avainhenkilöihin vaikuttamisesta keskityttiin tiedonantajien näkemyksiin siitä, millaiseksi he kokivat avainhenkilöihin vaikuttamisen komppaniatasolla omassa joukossaan. Lisäksi selvitettiin mitkä tekijät edesauttoivat tai haittasivat sanomien perille menoa KLE- tilanteessa ja miten avainhenkilöihin vaikuttamisella voidaan parantaa tilannekuvaa toiminta-alueella. Edellä mainitut kokonaisuudet selvittämällä ratkaistiin tutkimuksen pääkysymys; Mitkä tekijät vaikuttavat KLE-tilanteen onnistumiseen? Tutkimuksen tiedonantajat ovat palvelleet ISAF- ja UNIFIL-operaatioissa vuosina 2011–2014. Aineisto kerättiin avoimella kyselyllä verkkopohjaisella Webropol-ohjelmistolla. Kyselyyn vastasi 13 vastaajaa. Kaikkien vastaajien rotaation kesto oli kuusi kuukautta. Vastaajat rajattiin nuorempiin upseereihin, jotka ovat palvelleet pääosin joukkueenjohtajatasoisissa tehtävissä operaationsa aikana. Aineisto analysoitiin teoriaohjaavan sisällönanalyysin keinoin. Tutkimuksen perusteella voidaan sanoa, että avainhenkilöihin vaikuttaminen mielletään komppaniatasolla kontaktien ja suhteiden luomiseksi omassa yhteisössään vaikutusvaltaisten yksilöiden kanssa. Näillä kontakteilla mahdollistetaan tiedonhankinta, tiedottaminen ja tilannekuvan parantaminen sekä strategisen kommunikaation perusviestin, eli narratiivin jalkauttaminen. KLE on tapa vaikuttaa haluttuun kohdeyleisöön tiettyjen avainasemassa olevien johtajien, kuten esimerkiksi uskonnollisten johtajien ja kyläpäälliköiden kautta. Avainhenkilöihin vaikuttamisen onnistumiseen liittyy monia tekijöitä. Näistä tekijöistä keskeisimpiä ovat kulttuuritietoisuus, valmistautuminen ja valmistavakoulutus, sekä henkilökohtaiset valmiudet toimia viestintätilanteessa. Johtopäätöksinä voidaan todeta, että valmistautuminen KLE-tilanteeseen ei ole vakioitu toimenpide ja valmistautumiseen liittyvät toimenpiteet riippuvat suorittajan henkilökohtaisesta osaamisesta ja motivaatioista. Tilanteisiin valmistauduttaessa tulisi huomioida tilanteen harjoittelu, jos mahdollista. Lisäksi kulttuuritietoisuuskoulutuksen merkitystä ei voida korostaa liiaksi. Valmistavassa koulutuksessa on syytä harkita KLE-koulutusta tai vähintään jonkin asteisten neuvottelutaitojen koulutusta, osana joukkueenjohtajien tai vastaavan tasoisten tehtävien rotaatiokoulutusta.

Topographic mapping skills for secondary students.

Ofrece a los estudiantes la comprensión de conocimientos geográficos y la posibilidad de practicar las habilidades topográficas. Incluye, además de mapas de gran formato organizados por continentes y material complementario sobre población y clima, imágenes de satélite y fotografías aéreas y al nivel del suelo. También, contiene actividades graduadas para ayudar a leer, interpretar y analizar los mapas topográficos.

Struktur-Dynamik-Beziehungen in amorphen festen Lösungen

Feste Lösungen homogen dispergierter Wirkstoffmoleküle in amorphen Polymermatrizen sind wichtige Materialien in vielen pharmazeutischen Anwendungen, bei denen eine kontrollierte Abgabe wasserunlöslicher Wirkstoffe in wässrige Systeme eine Rolle spielt. Die intermolekulare Bindungs-stärke zwischen Polymer- und Wirkstoffmolekülgruppen bestimmt die Stabilität der festen Lösung und steuert somit die biologische Aktivität der Wirkstoffmoleküle. In festen Lösungen, die aus acryl-säurehaltigen Copolymeren (Protonendonoren) und basischen Wirkstoffmolekülen (Protonenakzepto-ren) hergestellt werden, sind intermolekulare Wasserstoffbrücken zwischen den Systemkomponenten Triebkraft für die Bildung einer stabilen homogenen Dispersion und für die Entstehung struktureller Merkmale zwischen den Molekülgruppen der Systemkomponenten. Zudem ist die Bindungsstärke der Wasserstoffbrücken im Hinblick auf die kontrollierte Abgabe der Wirkstoffe von Bedeutung. Da dynamische chemische Gleichgewichte bei der Bildung der Wasserstoffbrücken eine wichtige Rolle spielen müssen neben strukturellen Parametern auch dynamische Faktoren beleuchtet werden. Ziel dieser Arbeit ist neben der Ermittlung von intermolekularen Bindungsstärken vor allem die Identifika-tion struktureller Verhältnisse zwischen den Systemkomponenten auf molekularer Ebene. Die Be-stimmung der Abhängigkeit dieser Parameter von der Struktur der verwendeten Polymere und einer Vielzahl weiterer Einflüsse wie z.B. Feuchtigkeit, Lagerdauer oder Wirkstoffkonzentration soll ein kontrolliertes Design fester Lösungen mit definierten anwendungsspezifischen Eigenschaften ermögli-chen. Temperaturabhängige 1H-Festkörper-MAS-NMR (Magic Angle Spinning Nuclear Magnetic Resonance) Experimente an festen Lösungen mit unterschiedlichen Copolymer-Zusammensetzungen weisen die Existenz dynamischer chemischer Gleichgewichte in den komplexen Wasserstoffbrücken-netzwerken nach. Veränderungen in der chemischen Verschiebung und in der Linienform der Reso-nanzlinien acider Protonen erlauben einen tiefen Einblick in die Architektur dieser Netzwerke und legen die Bindungsverhältnisse unter Berücksichtigung der Polymerchemie und der Mobilität der Systemkomponenten dar, wobei die Befunde mithilfe quantenchemischer Rechnungen untermauert werden können. Die Gegenwart acider Protonen ermöglicht einen einfachen 1H-2H-Austausch, wor-aufhin mithilfe rotorsynchronisierter temperaturabhängiger 2H-MAS-NMR Experimente die Wasser-stoffbrückenbindungsstärke bestimmt werden kann. Mit 1H-1H-Korrelationsexperimenten (Doppelquantenspektroskopie) stehen Methoden für die Bestimmung homonuklearer dipolarer 1H-1H-Kopplungen zur Verfügung, die strukturelle Aussagen aufgrund von bevorzugten räumlichen Kontak-ten bestimmter Molekülgruppen ermöglichen. Weiterhin können diese Experimente verwendet werden, um Wasserstoffbrücken zwischen Polymergruppen von Polymer-Wirkstoff-Wasserstoffbrücken zu unterscheiden, wodurch eine quantitative Beschreibung des Bindungsnetzwerks und der Konkurrenz-prozesse zwischen den einzelnen wasserstoffverbrückten Spezies ermöglicht wird. Eine Kristallisation der Wirkstoffmoleküle ist in vielen Anwendungen unerwünscht, da sie die biologische Verfügbarkeit des Wirkstoffs reduzieren. Mit 1H-Festkörper-MAS-NMR Experimenten können kristalline von amorph dispergierten Wirkstoffmolekülen unterschieden werden, wodurch eine Quantifizierung der Destabilisierungsprozesse ermöglicht wird, die durch Exposition der festen Lösungen mit Wasserdampf ausgelöst werden können. Die Zeit- und Konzentrationsabhängigkeit der Wasseraufnahme kann mit NMR-Experimenten verfolgt werden, wobei unterschiedlich mobile Was-serspezies an unterschiedlichen Bindungsorten identifiziert werden können, was zum molekularen Verständnis der Destabilisierungsprozesse beiträgt. Zusätzlich wird die Mobilität der Wirkstoffmole-küle bestimmt, die sich – wie auch die Wirkstoffkonzentration - als wichtige Größe in der Beschrei-bung der Destabilisierung erweist. Aufbauend auf den Beobachtungen wird ein Zusammenhang zwischen der Copolymerzusammensetzung und einer kritischen Wirkstoffkonzentration hergestellt, der für die Anwendungen amorpher fester Lösungen in biologischen Systemen von großer Bedeutung ist.

Effect of mesh distortion on the accuracy of high order vorticity-velocity CFD approaches

The numerical solution of the incompressible Navier-Stokes equations offers an alternative to experimental analysis of fluid-structure interaction (FSI). We would save a lot of time and effort and help cut back on costs, if we are able to accurately model systems by these numerical solutions. These advantages are even more obvious when considering huge structures like bridges, high rise buildings or even wind turbine blades with diameters as large as 200 meters. The modeling of such processes, however, involves complex multiphysics problems along with complex geometries. This thesis focuses on a novel vorticity-velocity formulation called the Kinematic Laplacian Equation (KLE) to solve the incompressible Navier-stokes equations for such FSI problems. This scheme allows for the implementation of robust adaptive ordinary differential equations (ODE) time integration schemes, allowing us to tackle each problem as a separate module. The current algortihm for the KLE uses an unstructured quadrilateral mesh, formed by dividing each triangle of an unstructured triangular mesh into three quadrilaterals for spatial discretization. This research deals with determining a suitable measure of mesh quality based on the physics of the problems being tackled. This is followed by exploring methods to improve the quality of quadrilateral elements obtained from the triangles and thereby improving the overall mesh quality. A series of numerical experiments were designed and conducted for this purpose and the results obtained were tested on different geometries with varying degrees of mesh density.

Effect of high order interpolation in the stability and efficiency of the time-integration process in vorticity-velocity CFD algorithms

The numerical solution of the incompressible Navier-Stokes Equations offers an effective alternative to the experimental analysis of Fluid-Structure interaction i.e. dynamical coupling between a fluid and a solid which otherwise is very complex, time consuming and very expensive. To have a method which can accurately model these types of mechanical systems by numerical solutions becomes a great option, since these advantages are even more obvious when considering huge structures like bridges, high rise buildings, or even wind turbine blades with diameters as large as 200 meters. The modeling of such processes, however, involves complex multiphysics problems along with complex geometries. This thesis focuses on a novel vorticity-velocity formulation called the KLE to solve the incompressible Navier-stokes equations for such FSI problems. This scheme allows for the implementation of robust adaptive ODE time integration schemes and thus allows us to tackle the various multiphysics problems as separate modules. The current algorithm for KLE employs a structured or unstructured mesh for spatial discretization and it allows the use of a self-adaptive or fixed time step ODE solver while dealing with unsteady problems. This research deals with the analysis of the effects of the Courant-Friedrichs-Lewy (CFL) condition for KLE when applied to unsteady Stoke’s problem. The objective is to conduct a numerical analysis for stability and, hence, for convergence. Our results confirmthat the time step ∆t is constrained by the CFL-like condition ∆t ≤ const. hα, where h denotes the variable that represents spatial discretization.

S100A4 is a molecular mediator of endometrial carcinoma invasion

The molecular mechanisms of endometrail cancer invasion are poorly understood. S100A4, a member of the S100 Ca2+-binding protein family, was identified by oligonucleotide microarray qRT-PCR, and IHC, to be highly overexpressed in invasive endometrial carcinomas compared to non-invasive tumors. HEC-1A endometrial cancer cells transfected with S100A4 siRNA had undetectable S100A4 protein, decreased migration and invasion. The mechanism of S100A4 upregulation in endometrial cancer remains unclear. Methylation of the S100A4 gene was detected in benign endometrial glands and grade 1 tumors with no S100A4 expression. In contrast, grade 3 endometrioid tumors with high S100A4 expression showed no methylation of the gene. 5-Aza-2'-deoxycytidine, an inhibitor of DNA methyltransferase, induced the expression of S100A4 in the less invasive EC cell line, KLE, in which the S100A4 gene is hypermethylated and minimally expressed. S100A4 was induced during TGF-β1-triggered cell scattering in HEC-1A cells, in which S100A4 was demethylated. Transfection of HEC-1A cells with S100A4 siRNA significantly reduced the effect of TGF-β1 on basal migration and invasion. Our preliminary data suggested that this upregulation was mediated by the transcription factor Snail. One Snail binding consensus site was found in the region where DNA methylation was closely correlated with S100A4 gene expression. Chromatin immunoprecipitation assay confirmed the binding of Snail to this consensus site in HEC-1A cells. In SPEC2 endometrial cancer cells, loss of Snail leads to repressed S100A4 gene expression. Similar to S100A4, Snail was overexpressed in aggressive endometrial tumors. Our study suggested that the S100A4 gene was demethylated and further upregulated by the TGF-β1 and Snail pathway in invasive endometrial cancer. S100A4 could potentially serve as a good molecular marker for invasiveness and a target for therapeutic intervention for advanced endometrial cancer. ^

Guardrail testing program II: final report.

Federal Highway Administration, Eastern Federal Lands Highway Division, Sterling, Va.

L'expédition d'Egypte /

On added t.p.: Septième série.--Format in-80 cavalier ill.

School of Nursing Class of 1987

Top Row: Douglas G. Pointon, Anne M. Laliberte, Anne T. Reaume, Karen R. Anderson, Margaret A. Mehall, Laura Meintel(Cepko), Sharon M. Milberger, Felicia I. Kle??, Pamela J. DcKeyser, Kathryn G. Maudlin, Mary C. Downey, Julie A. Gergen, Anne K. Hubling, Helen Mourao, Deborah L. Dubrul, Sarah E. Whorf

Row 2: Andrea Mitchell, Karen E. Grost, Paula V. Nersesian, Kelly A. Fleming, Mary Beth Morton, Lynda L. Cooley, Cynthia A. Wandzel, Deborah L. Bach, Karen A. Schwartz, Rhonda G. Pasma, Lesley M. Shafer, Michelle A. Kauer, Mary Jo Raftery, Carol A. Hammell, Josephine G. Ratcliffe

Row 3: Shon A. Pilarski, Julie S. Peritz, Terri L. McPherson, Tina T. chandler, Janet C. Pinkerton, Rosanna M. Knapp, Lisa A. Krukowski, Madelyn L. Nichols, Jaleh Shafii, Elizabeth A. Beer, Molly A. Finn, Dyann E. Botsford, Kathryn J. Meier, Angela L. Bruder (Crane), Herlinda Olive-Downs, Laura B. Bailey

Row 4: Laura L. Brooks, Lisa K. Feezell

Row 5: Cindy L. Harvey, Kerri A. Bacsanyi, Diane R. Cepko, Sheila E. Falk, Marylin A. Jeromin, Marianne Gerard, Sharon L. Podeszwa, Lynette A. LaPratt, Mary Ann Williams, Diana L. Faulk, Christine L. Henriksen, Sharon M. LaMacchia

Row 6: Deborah A. ranazzi (Maxim), Debra J. Mitchell, Holly B. O'Brien, Elaine K. Hebda, Jeanne L. Bruff, Crystal M. Emery, Cleola Hinton, Kathleen T. Hutton, Holly L. Nelson, Karen F. Kraker

Row 7: Meghan A. Sweeney, Christine M. Olree, Marlynn J. Marroso, Toni L. Lowery, Catherine L. Carroll, Elisabeth A. Pennington, Shake Ketefian, Rhetaugh G. Dumas, Janice B. Lindberg, Marlene Rutledge, Kimberley A. Vnuk, Anne M. Walsh, Rae Ann Vander Weide, Cheryl L. Boyd

Row 8: Renee M. Marks, Janine M. Simon, Renee A. Bowles, Linda Kurpinski-Nabozny, Teresa E. Ohman, Joanna E. Bok, Jodi F. Siegel, Janeen M. Chebli, Susan M. Williamson, Mary M. Fedewa, Rose Marie Stacey, Angela J. DeWitt, Kim E. Whelan, Lyndall P. Miller

Row 9: Jean M. Dziurgot, Amy J. Elwart, Lorrie A. Sheck, Amy A. Plasman, Mary L. Schuette, Susan K. Bowen, Heather A. Woodward, Luann N. Richert, Laurie J. Schlukebir, Linda L. Stevenson(Said), Carolyn N. Hartke, Rebecca L. Evans, Kathryn A. Savage, Kathryn A. Sailus (Linden), Heidi Deininger, Jennifer J. Eppley

The Effect of Foam Core Density on the Flexural and Axial Behaviour of Sandwich Panels of Varying Slenderness with Natural Flax-FRP and Glass-FRP Composite Skins

This study investigates the effect of foam core density and skin type on the behaviour of sandwich panels as structural beams tested in four-point bending and axially compressed columns of varying slenderness and skin thickness. Bio-composite unidirectional flax fibre-reinforced polymer (FFRP) is compared to conventional glass-FRP (GFRP) as the skin material used in conjunction with three polyisocyanurate (PIR) foam cores with densities of 32, 64 and 96 kg/m3. Eighteen 1000 mm long flexural specimens were fabricated and tested to failure comparing the effects of foam core density between three-layer FFRP skinned and single-layer GFRP skinned panels. A total of 132 columns with slenderness ratios (kLe/r) ranging from 22 to 62 were fabricated with single-layer GFRP skins, and one-, three-, and five-layer FFRP skins for each of the three foam core densities. The columns were tested to failure in concentric axial compression using pinned-end conditions to compare the effects of each material type and panel height. All specimens had a foam core cross-section of 100x50 mm with 100 mm wide skins of equal thickness. In both flexural and axial loading, panels with skins comprised of three FFRP layers showed equivalent strength to those with a single GFRP layer for all slenderness ratios and core densities examined. Doubling the core density from 32 to 64 kg/m3 and tripling the density to 96 kg/m3 led to flexural strength increases of 82 and 213%, respectively. Both FFRP and GFRP columns showed a similar variety of failure modes related to slenderness. Low slenderness of 22-25 failed largely due to localized single skin buckling, while those with high slenderness of 51-61 failed primarily by global buckling followed by secondary skin buckling. Columns with intermediate slenderness experienced both localized and global failure modes. High density foam cores more commonly exhibited core shear failure. Doubling the core density of the columns resulted in peak axial load increases, across all slenderness ratios, of 73, 56, 72 and 71% for skins with one, three and five FFRP layers, and one GFRP layer, respectively. Tripling the core density resulted in respective peak load increases of 116, 130, 176 and 170%.

Vortex Shedding Dynamics in Long Aspect-Ratio Aerodynamics Bodies

The focus of the current dissertation is to study qualitatively the underlying physics of vortex-shedding and wake dynamics in long aspect-ratio aerodynamics in incompressible viscous flow through the use of the KLE method. We carried out a long series of numerical experiments in the cases of flow around the cylinder at low Reynolds numbers. The study of flow at low Reynolds numbers provides an insight in the fluid physics and also plays a critical role when applying to stalled turbine rotors. Many of the conclusions about the qualitative nature of the physical mechanisms characterizing vortex formation, shedding and further interaction analyzed here at low Re could be extended to other Re regimes and help to understand the separation of the boundary layers in airfoils and other aerodynamic surfaces. In the long run, it aims to provide a better understanding of the complex multi-physics problems involving fluid-structure-control interaction through improved mathematical computational models of the multi-physics process. Besides the scientific conclusions produced, the research work on streamlined and bluff-body condition will also serve as a valuable guide for the future design of blade aerodynamics and the placement of wind turbines and hydrakinetic turbines, increasing the efficiency in the use of expensive workforce, supplies, and infrastructure. After the introductory section describing the main fields of application of wind power and hydrokinetic turbines, we describe the main features and theoretical background of the numerical method used here. Then, we present the analysis of the numerical experimentation results for the oscillatory regime right before the onset of vortex shedding for circular cylinders. We verified the wake length of the closed near-wake behind the cylinder and analysed the decay of the wake at the wake formation region, and then studied the St-Re relationship at the Reynolds numbers before the wake sheds compared to the experimental data. We found a theoretical model that describes the time evolution of the amplitude of fluctuations in the vorticity field on the twin vortex wake, which accurately matches the numerical results in terms of the frequency of the oscillation and rate of decay. We also proposed a model based on an analog circuit that is able to interpret the concerning flow by reducing the number of degrees of freedom. It follows the idea of the non-linear oscillator and resembles the dynamics mechanism of the closed near-wake with a common configured sine wave oscillator. This low-dimensional circuital model may also help to understand the underlying physical mechanisms, related to vorticity transport, that give origin to those oscillations.