Caminhos da tradução: Cavafy, Montale e Jorge de Sena -Divagações-

Revista Lusófona de Línguas, Culturas e Tradução

A metamorfose seniana: poesia e crítica na obra de Jorge de Sena

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

As representações do intelectual na correspondência entre Jorge de Sena e Vergílio Ferreira ― (1950‐1975)

The purpose of this article is to discuss the representations of intellectual in the epistolary production of Jorge de Sena (1919‐1978), more specifically in correspondence with Virgil Ferreira (1916‐1997), which occurred between the years 1950 to 1975. Some topics, such as the condition of intellectual dictatorship, the position of the writer and his relations with the aesthetics of Neo‐Realism and the condition of exile, are important topics that make up most of the concerns of both writers.

Epimeteu, ou o Homem que pensava depois: uma «fantasia mitológica» de Jorge de Sena

Pretende-se, neste texto, oferecer uma leitura da peça seniana em um acto, Epimeteu, ou o Homem que Pensava Depois, que, num complexo e original registo trágico-fársico, conjuga, com grande signifi cado dramático e efi cácia teatral, mito e fantasia.

O Desejado (Jacob e o Anjo) [de Régio] e o O Indesejado [de Sena]

A peça de José Régio, Jacob e o Anjo, considerada por Alberto de Serpa "a mais forte peça de todo o nosso teatro" (c.i. a Jorge de Sena, de 7 Jul. 1948), evidencia-se, ao contrário do que se poderia suspeitar relativamente ao título desta comunicação (onde é directa a referência à peça de 1949, El-Rei Sebastião, cuja dignidade de linguagem Óscar Lopes viria a comparar, em 1969, à de Frei Luis de Sousa de Garrett), como uma das principais referências imediatas – ou como a principal”interlocutora” -- da peça magna de Jorge de Sena O Indesejado, António Rei.

Estagiar na Babel

Relatório de Estágio apresentado para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Edição de Texto

Coroa da terra: a poesia como (re)criação do mundo

This monograph is aimed at reflecting the internal structure of the book Coroa da Terra (1946), the Portuguese poet Jorge de Sena (1919-1978), investigating for this, the guiding criteria for the ordering of poems. Starting from a question posed by an author paratext, we considered the possibility that the book is constituted as a unit of poetic path, in which each poem comprises a stretch of the pilgrimage undertaken by the poet toward the crown of the Earth. Moreover, from the epigraph of the book and the Preface (1960) of 1st edition of Poesia I (1961), we consider the idea that the Coroa da Terra is a search for truth, or even that the pilgrimage made by the poet is on the trail of a poetic word conscious and therefore ethically responsible. This search would set the poetic language of testimony, from which derive two other important vectors for the exegesis of poetry seniana: metamorphosis and pilgrimage. Upholding the unity of the book would be the language in dialectical flow as a formal procedure, which enables the poet be an expression in constant motion. To check the validity of our hypothesis, we conducted an analysis of four poems in sequential order (―Purgatório‖, ―Suma Teológica‖, ―Os trabalhos e os dias‖, ―Espiral‖). To them, it was added to analyze the poem ―Metamorfose‖, poem 23rd of the Coroa da Terra, which acted as a reference point and as close to the research by presenting a character's thought seniano synthesis. It was found that the idea of unity is sustained when we consider Coroa da Terra as a journey of formative poetic direction

La cadena de distribución y la competitividad de las exportaciones latinoamericanas: las exportaciones de cerámica uruguaya por Metzen y Sena

Incluye Bibliografía

Aripiprazole for Patients with Schizophrenia and Schizoaffective Disorder: An Open-Label, Randomized, Study Versus Haloperidol

Introduction: Aripiprazole, a dopamine D(2) receptor partial agonist, has also partial agonist activity at serotonin (5-HT)(1A) receptors and antagonist activity at 5-HT(2A) receptors. Methods: In this 8-week, multicenter, randomized, parallel-group, open-label, flexible-dose study, patients diagnosed with schizophrenia or schizoaffective disorder were randomized to aripiprazole 15-30 mg/day or haloperidol 10-15 mg/day. Results: Patients treated with both aripiprazole and haloperidol improved from baseline in Positive and Negative Syndrome Scale total, positive, and negative scores as well as in Clinical Global Impressions scores (all P<.001). At the end of the study, the percentage of patients classified as responders-according to >= 40% reduction in the Positive and Negative Syndrome Scale negative subscale score-was significantly higher in the aripiprazole group (20%) than in the haloperidol group (0%) (P<.05). Additionally, a higher number of patients receiving haloperidol required more anticholinergic medications (P<.001) than aripiprazole-treated patients, whereas more aripiprazole (45.5%) than haloperidol-treated patients (12.9%) required benzodiazepines (P=.002). At endpoint, rates of preference of medication were higher in the aripiprazole group (63.2%) than in the haloperidol group (21.7%), as expressed by patients and caregivers (P=.001). Conclusion: Aripiprazole and haloperidol had similar efficacy in terms of reduction of overall psychopathology. Although aripiprazole has been demonstrated to be superior concerning negative symptoms and in terms of tolerability (extrapyramidal symptoms) and preferred by patients and caregivers than haloperidol, significantly more aripiprazole-treated patients required benzodiazepines.

Macrophage and TGF-beta immunohistochemical expression in Jorge Lobo`s disease

Jorge Lobo`s disease, or lacaziosis, is a chronic deep mycosis that clinically manifests as solid, variable-sized nodular parakeloidal lesions. Few studies have characterized the in situ cellular and humoral immune response, especially the involvement of cytokines with immunosuppressive effects such as TGF-beta. The objective this paper was to analyze the expression of TGF-beta in cutaneous lesions in lacaziosis and investigate its importance in the etiopathogy of the disease. The results indicate that the abundance of collagen bands, together with weak immunolabeling for CD68 seen in macrophages, indicates a concomitant effect of TGF-beta inhibiting macrophages and inducing fibrosis, which is responsible for the keloid aspect frequently acquired by these lesions. Finally, the evolution of the infection supports the hypothesis that TGF-beta plays a fundamental role in the etiopathology of Lacazia loboi infection, either by inhibiting the cellular immune response mainly mediated by macrophages or by inducing fibrosis. Further studies are necessary to better characterize the phenotype of the inflammatory infiltrate as well as the participation of other cytokines and growth factors in the tissue response of the host in Jorge Lobo`s disease. (C) 2008 Published by Elsevier Inc.

Immunohistochemical study of Langerhans cells in cutaneous lesions of the Jorge Lobo`s disease

Jorge Lobo`s disease is a chronic infection caused by the fungus Lacazia loboi endemic in South America. The infection is characterized by the appearance of parakeloidal, ulcerated or verrucous nodular or plaque-like cutaneous lesions. The histopathological aspect is characterized by poorly organized granulomas with histiocytes and multinucleated giant cells. Little is known about local immune response in lobomycosis skin lesions. Thirty-three skin biopsies from patients with Jorge Lobo`s disease were selected from Ambulatory of Dermatology, UFPA. The control group was constituted by ten biopsies from normal skin. Langerhans cells were identified by immunohistochemistry using anti-CD1a antibody (Serotec). The number of positive cells was statistically analyzed. Langerhans cells were visualized along the epidermis in biopsies from Jorge Lobo`s disease and the morphology and the number of Langerhans cells did not differ from normal skin (p > 0.05). In Jorge Lobo`s disease, this cell population probably presents some escape mechanism of the local immune system to evade the antigen presentation by those cells. (C) 2010 Published by Elsevier B.V.

Detection of cytokines and nitric oxide synthase in skin lesions of Jorge Lobo`s disease patients

Studies investigating the immunopathological aspects of Jorge Lobo`s disease have shown that the inflammatory infiltrate consists mainly of histiocytes and multinucleated giant cells involving numerous yeast-like cells of Lacazia loboi, with the T lymphocytes more common than B lymphocytes and plasma cells. The quantification of cytokines in peripheral blood mononuclear cells culture supernatant has revealed alterations in the cytokines profile, characterized by predominance of a Th2 profile. In view of these findings and of the role of cytokines in cell interactions, the objective of the present study was to investigate the presence of the cytokines IL-10, TGF-ss 1 and TNF-alpha, as well as iNOS enzyme in granulomas induced by L. loboi. Histological sections obtained from skin lesions of 16 patients were analyzed by immunohistochemistry for the presence of these cytokines and iNOS. The results showed that TGF-ss 1 was the cytokine most frequently expressed by cells present in the inflammatory infiltrate, followed by IL-10. There was a minimum to discrete positivity of cells expressing TNF-alpha and iNOS. The results suggest that the presence of immunosuppressive cytokines in skin lesions of patients with the mycosis might be responsible for the lack of containment of the pathogen as demonstrated by the presence of numerous fungi in the granuloma.