744 resultados para Integrated seminar
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A partir do ano de 2012, lança-se uma proposta de reestruturação no Ensino Mé- dio no Estado do Rio Grande do Sul. Surge nessa proposta um elemento novo na grade curricular chamado de Seminário Integrado. Esse tem por objetivo aliar a formação geral à parte diversificada do currículo através de um planejamento interdisciplinar voltado à pesquisa. Diante desse cenário surge a motivação para elaborar esse trabalho, nele apresenta-se quatro atividades interdisciplinares relacionando a matemática com outras disciplinas. Nossa proposta é que essas atividades possam servir como uma possível base para elaboração e/ou estruturação de atividades nos Seminários Integrados. Junto com cada atividade apresentamos uma proposta de pesquisa relacionada à prática social, bem como em quais sentidos essas atividades poderão preparar o jovem para ser inserido no mercado de trabalho. O material elaborado pelos professores envolvidos e a escolha dos métodos de ensino utilizados são subsidiados por uma pesquisa bibliográfica que fizemos a respeito do tema interdisciplinaridade. As atividades elaboradas foram aplicadas em duas turmas de terceiro ano do Ensino Médio, em uma escola particular na cidade de Pelotas, Rio Grande do Sul. Apresentamos alguns dados que consideramos relevantes em termos de resultados relacionados ao ganho pedagógico.
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Contiene organización de los trabajos, resumen de los debates y recomendaciones y conclusiones. Incluye además, definición de términos utilizados; criterios para definir las principales características y necesidades de las zonas altas de la Región Andina; lista de participantes y lista de documentos presentados en el Seminario.
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Includes bibliography
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Wednesday 9th April 2014 Speaker(s): Guus Schreiber Time: 09/04/2014 11:00-11:50 Location: B32/3077 File size: 546Mb Abstract In this talk I will discuss linked data for museums, archives and libraries. This area is known for its knowledge-rich and heterogeneous data landscape. The objects in this field range from old manuscripts to recent TV programs. Challenges in this field include common metadata schema's, inter-linking of the omnipresent vocabularies, cross-collection search strategies, user-generated annotations and object-centric versus event-centric views of data. This work can be seen as part of the rapidly evolving field of digital humanities. Speaker Biography Guus Schreiber Guus is a professor of Intelligent Information Systems at the Department of Computer Science at VU University Amsterdam. Guus’ research interests are mainly in knowledge and ontology engineering with a special interest for applications in the field of cultural heritage. He was one of the key developers of the CommonKADS methodology. Guus acts as chair of W3C groups for Semantic Web standards such as RDF, OWL, SKOS and REFa. His research group is involved in a wide range of national and international research projects. He is now project coordinator of the EU Integrated project No Tube concerned with integration of Web and TV data with the help of semantics and was previously Scientific Director of the EU Network of Excellence “Knowledge Web”.
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Includes bibliography
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Editorial remarks.-- Open discussion: public policies for sustainable development.-- Meetings: Workshop for Managers of River Basin Organizations in Latin America and the Caribbean ; General Assembly of the International Network of Basin Organizations ; Seminar workshop on environmental accounting for water resources in Chile.-- Future activities.-- Courses.-- CELAA, CINARA and IMTA.-- Internet and WWW News
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Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of oral cancer. Hence, in this study we have investigated the proteomic and peptidomic profiles by combining an orthotopic murine model of oral squamous cell carcinoma (OSCC), mass spectrometry-based proteomics and biological network analysis. Our results indicated the up-regulation of proteins involved in actin cytoskeleton organization and cell-cell junction assembly events and their expression was validated in human OSCC tissues. In addition, the functional relevance of talin-1 in OSCC adhesion, migration and invasion was demonstrated. Taken together, this study identified specific processes deregulated in oral cancer and provided novel refined OSCC-targeting molecules.
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A miniaturised gas analyser is described and evaluated based on the use of a substrate-integrated hollow waveguide (iHWG) coupled to a microsized near-infrared spectrophotometer comprising a linear variable filter and an array of InGaAs detectors. This gas sensing system was applied to analyse surrogate samples of natural fuel gas containing methane, ethane, propane and butane, quantified by using multivariate regression models based on partial least square (PLS) algorithms and Savitzky-Golay 1(st) derivative data preprocessing. The external validation of the obtained models reveals root mean square errors of prediction of 0.37, 0.36, 0.67 and 0.37% (v/v), for methane, ethane, propane and butane, respectively. The developed sensing system provides particularly rapid response times upon composition changes of the gaseous sample (approximately 2 s) due the minute volume of the iHWG-based measurement cell. The sensing system developed in this study is fully portable with a hand-held sized analyser footprint, and thus ideally suited for field analysis. Last but not least, the obtained results corroborate the potential of NIR-iHWG analysers for monitoring the quality of natural gas and petrochemical gaseous products.
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High-throughput screening of physical, genetic and chemical-genetic interactions brings important perspectives in the Systems Biology field, as the analysis of these interactions provides new insights into protein/gene function, cellular metabolic variations and the validation of therapeutic targets and drug design. However, such analysis depends on a pipeline connecting different tools that can automatically integrate data from diverse sources and result in a more comprehensive dataset that can be properly interpreted. We describe here the Integrated Interactome System (IIS), an integrative platform with a web-based interface for the annotation, analysis and visualization of the interaction profiles of proteins/genes, metabolites and drugs of interest. IIS works in four connected modules: (i) Submission module, which receives raw data derived from Sanger sequencing (e.g. two-hybrid system); (ii) Search module, which enables the user to search for the processed reads to be assembled into contigs/singlets, or for lists of proteins/genes, metabolites and drugs of interest, and add them to the project; (iii) Annotation module, which assigns annotations from several databases for the contigs/singlets or lists of proteins/genes, generating tables with automatic annotation that can be manually curated; and (iv) Interactome module, which maps the contigs/singlets or the uploaded lists to entries in our integrated database, building networks that gather novel identified interactions, protein and metabolite expression/concentration levels, subcellular localization and computed topological metrics, GO biological processes and KEGG pathways enrichment. This module generates a XGMML file that can be imported into Cytoscape or be visualized directly on the web. We have developed IIS by the integration of diverse databases following the need of appropriate tools for a systematic analysis of physical, genetic and chemical-genetic interactions. IIS was validated with yeast two-hybrid, proteomics and metabolomics datasets, but it is also extendable to other datasets. IIS is freely available online at: http://www.lge.ibi.unicamp.br/lnbio/IIS/.
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Resource specialisation, although a fundamental component of ecological theory, is employed in disparate ways. Most definitions derive from simple counts of resource species. We build on recent advances in ecophylogenetics and null model analysis to propose a concept of specialisation that comprises affinities among resources as well as their co-occurrence with consumers. In the distance-based specialisation index (DSI), specialisation is measured as relatedness (phylogenetic or otherwise) of resources, scaled by the null expectation of random use of locally available resources. Thus, specialists use significantly clustered sets of resources, whereas generalists use over-dispersed resources. Intermediate species are classed as indiscriminate consumers. The effectiveness of this approach was assessed with differentially restricted null models, applied to a data set of 168 herbivorous insect species and their hosts. Incorporation of plant relatedness and relative abundance greatly improved specialisation measures compared to taxon counts or simpler null models, which overestimate the fraction of specialists, a problem compounded by insufficient sampling effort. This framework disambiguates the concept of specialisation with an explicit measure applicable to any mode of affinity among resource classes, and is also linked to ecological and evolutionary processes. This will enable a more rigorous deployment of ecological specialisation in empirical and theoretical studies.
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This article describes the design, implementation, and experiences with AcMus, an open and integrated software platform for room acoustics research, which comprises tools for measurement, analysis, and simulation of rooms for music listening and production. Through use of affordable hardware, such as laptops, consumer audio interfaces and microphones, the software allows evaluation of relevant acoustical parameters with stable and consistent results, thus providing valuable information in the diagnosis of acoustical problems, as well as the possibility of simulating modifications in the room through analytical models. The system is open-source and based on a flexible and extensible Java plug-in framework, allowing for cross-platform portability, accessibility and experimentation, thus fostering collaboration of users, developers and researchers in the field of room acoustics.
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Context. Analysis of ages and metallicities of star clusters in the Magellanic Clouds provide information for studies on the chemical evolution of the Clouds and other dwarf irregular galaxies. Aims. The aim is to derive ages and metallicities from integrated spectra of 14 star clusters in the Small Magellanic Cloud, including a few intermediate/old age star clusters. Methods. Making use of a full-spectrum fitting technique, we compared the integrated spectra of the sample clusters to three different sets of single stellar population models, using two fitting codes available in the literature. Results. We derive the ages and metallicities of 9 intermediate/old age clusters, some of them previously unstudied, and 5 young clusters. Conclusions. We point out the interest of the newly identified as intermediate/old age clusters HW1, NGC 152, Lindsay 3, Lindsay 11, and Lindsay 113. We also confirm the old ages of NGC 361, NGC 419, Kron 3, and of the very well-known oldest SMC cluster, NGC 121.