1000 resultados para Howard B. Hamilton
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The Howard B. Hamilton, MD, papers, MS 66, includes material from 1945-1997 related to the Atomic Bomb Casualty Commission (ABCC) and the Radiation Effects Research Foundation (RERF). Hamilton was the Chief of Clinical Laboratories for the Atomic Bomb Casualty Commission from 1956 until its dissolution in 1975. He served in the same capacity for the Radiation Effects Research Foundation, which succeeded the ABCC, until 1984. This collection encompasses this period of time in Dr. Hamilton's career, as well as his related scholarly work after his retirement from RERF. Dr. Hamilton donated his collection of letters, reprints, newspaper articles, photographs, memos, and ephemera to the John P. McGovern Historical Collections and Research Center between 1985 and 2002. The collection is in good condition and consists of 3.75 cubic feet (10 boxes).
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Bibliography: v.1, p. 347-351.
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Mode of access: Internet.
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front row left to right: Walter Sawyer, Harry B. Hutchins, Junius C. Beal; behind Beal: C. E. Johnson, ? , Howard Merrick
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Initial experiments were conducted using an in situ rat tibialis anterior (TA) muscle preparation to assess the influence of dietary antioxidants on muscle contractile properties. Adult Sprague-Dawley rats were divided into two dietary groups: 1) control diet (Con) and 2) supplemented with vitamin E (VE) and alpha -lipoic acid (alpha -LA) (Antiox). Antiox rats were fed the Con rats' diet (AIN-93M) with an additional 10,000 IU VE/kg diet and 1.65 g/kg alpha -LA. After an 8-wk feeding period, no differences existed (P > 0.05) between the two dietary groups in maximum specific tension before or after a fatigue protocol or in force production during the fatigue protocol. However, in unfatigued muscle, maximal twitch tension and tetanic force production at stimulation frequencies less than or equal to 40 Hz were less (P < 0.05) in Antiox animals compared with Con. To investigate which antioxidant was responsible for the depressed force production, a second experiment was conducted using an in vitro rat diaphragm preparation. Varying concentrations of VE and dihydrolipoic acid, the reduced form of -LA, were added either individually or in combination to baths containing diaphragm muscle strips. The results from these experiments indicate that high levels of VE depress skeletal muscle force production at low stimulation frequencies.
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Kirjallisuusarvostelu
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analizar el concepto de un Sistema de Gestión Ambiental (S.G.A), sus elementos y características, además de sus beneficios y aplicabilidad en empresas nacionales e internacionales.
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Este artículo tiene como objetivo describir la estructura del área de Responsabilidad Social de Pacific E&P, mediante un proceso que explique el funcionamiento y desarrollo de la estructura de RSE. Este trabajo se desarrolla bajo una matriz estratégica la cual incluye variables como: evolución del área (historia), plataforma estratégica (plan de acción que desarrolla una ventaja competitiva de la empresa), división del trabajo (Fragmentación de trabajo y especialización entre sus fuerzas laborales) y por último la coordinación del trabajo (sincronización de fuerzas laborales). Los resultados que se obtienen de este estudio mostrarán las distintas unidades de trabajo de la organización y la forma de trabajar de la misma, bajo el marco de la Responsabilidad Social Corporativa.
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In 1915 the United States Geological Survey published a folio by Calkins and Emmons on the geology of the Philipsburg Quadrangle, which adjoins the area now under study to the west. Geology of this portion of Montana had not been mapped previously; consequently the purpose of this thesis is to make a geological reconnaissance of the stratigraphy and structure of the area.
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Familial adenomatous polyposis (FAP) is an autosomal-dominant disease characterized by the development of hundreds of adenomatous polyps of the colorectum. Approximately 80% of FAP patients can be shown to have truncating mutations of the APC gene. To determine the cause of FAP in the other 20% of patients, MAMA (monoallelic mutation analysis) was used to independently examine the status of each of the two APC alleles. Seven of nine patients analyzed were found to have significantly reduced expression from one of their two alleles whereas two patients were found to have full-length expression from both alleles. We conclude that more than 95% of patients with FAP have inactivating mutations in APC and that a combination of MAMA and standard genetic tests will identify APC abnormalities in the vast majority of such patients. That no APC expression from the mutant allele is found in some FAP patients argues strongly against the requirement for dominant negative effects of APC mutations. The results also suggest that there may be at least one additional gene, besides APC, that can give rise to FAP.
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Includes index.
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Mode of access: Internet.
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Mode of access: Internet.