986 resultados para HEAD MODEL


Relevância:

70.00% 70.00%

Publicador:

Resumo:

The big proliferation of mobile communication systems has caused an increased concern about the interaction between the human body and the antennas of mobile handsets. In order to study the problem, a multiband antenna was designed, fabricated and measured to operate over two frequency sub bands 900 and 1800 MHz. After that, we simulated the same antenna, but now, in the presence of a human head model to analyze the head's influence. First, the influence of the human head on the radiation efficiency of the antenna has been investigated as a function of the distance between the head and the antenna and with the inclination of the antenna. Furthermore, the relative amount of the electromagnetic power absorbed in the head has been obtained.

Relevância:

70.00% 70.00%

Publicador:

Resumo:

The big proliferation of mobile communication systems has caused an increased concern about the interaction between the human body and the antennas of mobile handsets. In order to study the problem, a multiband antenna was designed, fabricated and measured to operate over two frequency sub bands 900 and 1800 MHz. After that, we simulated the same antenna, but now, in the presence of a human head model to analyze the head's influence. First, the influence of the human head on the radiation efficiency of the antenna has been investigated as a function of the distance between the head and the antenna and with the inclination of the antenna. Furthermore, the relative amount of the electromagnetic power absorbed in the head has been obtained. In this study the electromagnetic analysis has been performed via FDTD (Finite Difference Time Domain).

Relevância:

70.00% 70.00%

Publicador:

Resumo:

Brain activity can be measured with several non-invasive neuroimaging modalities, but each modality has inherent limitations with respect to resolution, contrast and interpretability. It is hoped that multimodal integration will address these limitations by using the complementary features of already available data. However, purely statistical integration can prove problematic owing to the disparate signal sources. As an alternative, we propose here an advanced neural population model implemented on an anatomically sound cortical mesh with freely adjustable connectivity, which features proper signal expression through a realistic head model for the electroencephalogram (EEG), as well as a haemodynamic model for functional magnetic resonance imaging based on blood oxygen level dependent contrast (fMRI BOLD). It hence allows simultaneous and realistic predictions of EEG and fMRI BOLD from the same underlying model of neural activity. As proof of principle, we investigate here the influence on simulated brain activity of strengthening visual connectivity. In the future we plan to fit multimodal data with this neural population model. This promises novel, model-based insights into the brain's activity in sleep, rest and task conditions.

Relevância:

70.00% 70.00%

Publicador:

Resumo:

The precise evaluation of electromagnetic field (EMF) distributions inside biological samples is becoming an increasingly important design requirement for high field MRI systems. In evaluating the induced fields caused by magnetic field gradients and RF transmitter coils, a multilayered dielectric spherical head model is proposed to provide a better understanding of electromagnetic interactions when compared to a traditional homogeneous head phantom. This paper presents Debye potential (DP) and Dyadic Green's function (DGF)-based solutions of the EMFs inside a head-sized, stratified sphere with similar radial conductivity and permittivity profiles as a human head. The DP approach is formulated for the symmetric case in which the source is a circular loop carrying a harmonic-formed current over a wide frequency range. The DGF method is developed for generic cases in which the source may be any kind of RF coil whose current distribution can be evaluated using the method of moments. The calculated EMFs can then be used to deduce MRI imaging parameters. The proposed methods, while not representing the full complexity of a head model, offer advantages in rapid prototyping as the computation times are much lower than a full finite difference time domain calculation using a complex head model. Test examples demonstrate the capability of the proposed models/methods. It is anticipated that this model will be of particular value for high field MRI applications, especially the rapid evaluation of RF resonator (surface and volume coils) and high performance gradient set designs.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

: In this work we derive an analytical solution given by Bessel series to the transient and one-dimensional (1D) bioheat transfer equation in a multi-layer region with spatially dependent heat sources. Each region represents an independent biological tissue characterized by temperature-invariant physiological parameters and a linearly temperature dependent metabolic heat generation. Moreover, 1D Cartesian, cylindrical or spherical coordinates are used to define the geometry and temperature boundary conditions of first, second and third kinds are assumed at the inner and outer surfaces. We present two examples of clinical applications for the developed solution. In the first one, we investigate two different heat source terms to simulate the heating in a tumor and its surrounding tissue, induced during a magnetic fluid hyperthermia technique used for cancer treatment. To obtain an accurate analytical solution, we determine the error associated with the truncated Bessel series that defines the transient solution. In the second application, we explore the potential of this model to study the effect of different environmental conditions in a multi-layered human head model (brain, bone and scalp). The convective heat transfer effect of a large blood vessel located inside the brain is also investigated. The results are further compared with a numerical solution obtained by the Finite Element Method and computed with COMSOL Multi-physics v4.1 (c). (c) 2013 Elsevier Ltd. All rights reserved.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Electroencephalography is mandatory to determine the epilepsy syndrome. However, for the precise localization of the irritative zone in patients with focal epilepsy, costly and sometimes cumbersome imaging techniques are used. Recent small studies using electric source imaging suggest that electroencephalography itself could be used to localize the focus. However, a large prospective validation study is missing. This study presents a cohort of 152 operated patients where electric source imaging was applied as part of the pre-surgical work-up allowing a comparison with the results from other methods. Patients (n = 152) with >1 year postoperative follow-up were studied prospectively. The sensitivity and specificity of each imaging method was defined by comparing the localization of the source maximum with the resected zone and surgical outcome. Electric source imaging had a sensitivity of 84% and a specificity of 88% if the electroencephalogram was recorded with a large number of electrodes (128-256 channels) and the individual magnetic resonance image was used as head model. These values compared favourably with those of structural magnetic resonance imaging (76% sensitivity, 53% specificity), positron emission tomography (69% sensitivity, 44% specificity) and ictal/interictal single-photon emission-computed tomography (58% sensitivity, 47% specificity). The sensitivity and specificity of electric source imaging decreased to 57% and 59%, respectively, with low number of electrodes (<32 channels) and a template head model. This study demonstrated the validity and clinical utility of electric source imaging in a large prospective study. Given the low cost and high flexibility of electroencephalographic systems even with high channel counts, we conclude that electric source imaging is a highly valuable tool in pre-surgical epilepsy evaluation.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Purpose: EEG is mandatory in the diagnosis of the epilepsy syndrome. However, its potential as imaging tool is still under estimated. In the present study, we aim to determine the prerequisites of maximal benefit of electric source imaging (ESI) to localize the irritative zone in patients with focal epilepsy. Methods: One hundred fifty patients suffering from focal epilepsy and with minimum 1 year postoperative follow-up were studied prospectively and blinded to the underlying diagnosis. We evaluated the influence of two important factors on sensitivity and specificity of ESI: the number of electrodes (low resolution, LR-ESI: <30 versus high resolution, HR-ESI: 128-256 electrodes), and the use of individual MRI (i-MRI) versus template MRI (t-MRI) as the head model. Findings: ESI had a sensitivity of 85% and a specificity of 87% when HR-ESI with i-MRI was used. Using LR-ESI, sensitivity decreased to 68%, or even 57% when only t-MRI was available. The sensitivity of HR-ESI/i-MRI compared favorably with those of MRI (76%), PET (69%) and ictal/interictal SPECT (64%). Interpretation: This study on a large patient group shows excellent sensitivity and specificity of ESI if 128 EEG channels or more are used for ESI and if the results are coregistered to the patient's individual MRI. Localization precision is as high as or even higher than established brain imagery techniques. HR-ESI appears to be a valuable additional imaging tool, given that larger electrode arrays are easily and rapidly applied with modern EEG equipment and that structural MRI is nearly always available for these patients.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Background: EEG is the cornerstone of epilepsy diagnostics and mandatory to determine the underlying epilepsy syndrome (e.g. focal vs idiopathic generalized). However, its potential as imaging tool is still underrecognized. In the present study, we aim to determine the prerequisites of maximal benefit of electric source imaging (ESI) to localize the irritative zone in patients with focal epilepsy. Methods: 150 patients suffering from focal epilepsy and with minimum 1 year post-operative follow-up were studied prospectively by reviewers blinded to the underlying diagnosis and outcome. We evaluated the influence of two important factors on sensitivity and specificity of ESI: the number of electrodes (low resolution, LR-ESI: \30 vs. high resolution, HR-ESI: 128-256 electrodes), and the use of individual MRI (i-MRI) vs. template MRI (t-MRI) as head model.Results: ESI had a sensitivity of 85% and a specificity of 87% when HR-ESI with i-MRI was used. Using LR-ESI, sensitivity decreased to 68%, or even 57% when only t-MRI was available. The sensitivity of HR-ESI/i-MRI compared favorably with those of MRI (76%), PET (69%) and ictal/interictal SPECT (64%).Interpretation: This study on a large patient group shows excellent sensitivity and specificity of ESI if 128 EEG channels or more are used for ESI and if the results are co-registered to the patient's individual MRI. Localization precision is as high as or even higher than established brain imaging techniques, providing excellent costeffectiveness in epilepsy evaluation. HR-ESI appears to be a valuable additional imaging tool, given that larger electrode arrays are easily and rapidly applied with modern EEG equipment and that structural MRI is nearly always available for these patients.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Since integral abutment bridges decrease the initial and maintenance costs of bridges, they provide an attractive alternative for bridge designers. The objective of this project is to develop rational and experimentally verified design recommendations for these bridges. Field testing consisted of instrumenting two bridges in Iowa to monitor air and bridge temperatures, bridge displacements, and pile strains. Core samples were also collected to determine coefficients of thermal expansion for the two bridges. Design values for the coefficient of thermal expansion of concrete are recommended, as well as revised temperature ranges for the deck and girders of steel and concrete bridges. A girder extension model is developed to predict the longitudinal bridge displacements caused by changing bridge temperatures. Abutment rotations and passive soil pressures behind the abutment were neglected. The model is subdivided into segments that have uniform temperatures, coefficients of expansion, and moduli of elasticity. Weak axis pile strains were predicted using a fixed-head model. The pile is idealized as an equivalent cantilever with a length determined by the surrounding soil conditions and pile properties. Both the girder extension model and the fixed-head model are conservative for design purposes. A longitudinal frame model is developed to account for abutment rotations. The frame model better predicts both the longitudinal displacement and weak axis pile strains than do the simpler models. A lateral frame model is presented to predict the lateral motion of skewed bridges and the associated strong axis pile strains. Full passive soil pressure is assumed on the abutment face. Two alternatives for the pile design are presented. Alternative One is the more conservative and includes thermally induced stresses. Alternative Two neglects thermally induced stresses but allows for the partial formation of plastic hinges (inelastic redistribution of forces). Ductility criteria are presented for this alternative. Both alternatives are illustrated in a design example.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Työn tavoitteena on tutkia metsäkoneen uuden harvesteripäämallin tuotekehitysprosessia valmistettavuuden näkökulmasta, selvittää tuotekehitysprosessin eri vaiheet sekä pyrkiä löytämään mahdolliset ongelmakohdat ja niihin ratkaisumallit. Työn tilanneella yrityksellä on pitkä historia ja kokemus harvesteripäiden tuotekehityksestä niin tuotteiden kuin tuotannon osalta. Dokumentoitu prosessi kuitenkin on puuttunut ja tämän työn tarkoituksena on tuottaa ko. prosessi valmistettavuuden huomioimisesta harvesteripään tuotekehitysprosessissa. Tutkimuksessa hyödynnetään alan kirjallisuutta ja yrityksen kokemuksia ja laaditaan niiden pohjalta dokumentointi tuotekehitysprosessin tueksi. Tutkimuksen perusteella havaittiin muutoksen hallinnan ja menetelmäsuunnittelun sekä hitsausten aiheuttamien muodonmuutosten olevan prosessin kriittisimpiä tekijöitä.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Le problème inverse en électroencéphalographie (EEG) est la localisation de sources de courant dans le cerveau utilisant les potentiels de surface sur le cuir chevelu générés par ces sources. Une solution inverse implique typiquement de multiples calculs de potentiels de surface sur le cuir chevelu, soit le problème direct en EEG. Pour résoudre le problème direct, des modèles sont requis à la fois pour la configuration de source sous-jacente, soit le modèle de source, et pour les tissues environnants, soit le modèle de la tête. Cette thèse traite deux approches bien distinctes pour la résolution du problème direct et inverse en EEG en utilisant la méthode des éléments de frontières (BEM): l’approche conventionnelle et l’approche réciproque. L’approche conventionnelle pour le problème direct comporte le calcul des potentiels de surface en partant de sources de courant dipolaires. D’un autre côté, l’approche réciproque détermine d’abord le champ électrique aux sites des sources dipolaires quand les électrodes de surfaces sont utilisées pour injecter et retirer un courant unitaire. Le produit scalaire de ce champ électrique avec les sources dipolaires donne ensuite les potentiels de surface. L’approche réciproque promet un nombre d’avantages par rapport à l’approche conventionnelle dont la possibilité d’augmenter la précision des potentiels de surface et de réduire les exigences informatiques pour les solutions inverses. Dans cette thèse, les équations BEM pour les approches conventionnelle et réciproque sont développées en utilisant une formulation courante, la méthode des résidus pondérés. La réalisation numérique des deux approches pour le problème direct est décrite pour un seul modèle de source dipolaire. Un modèle de tête de trois sphères concentriques pour lequel des solutions analytiques sont disponibles est utilisé. Les potentiels de surfaces sont calculés aux centroïdes ou aux sommets des éléments de discrétisation BEM utilisés. La performance des approches conventionnelle et réciproque pour le problème direct est évaluée pour des dipôles radiaux et tangentiels d’excentricité variable et deux valeurs très différentes pour la conductivité du crâne. On détermine ensuite si les avantages potentiels de l’approche réciproquesuggérés par les simulations du problème direct peuvent êtres exploités pour donner des solutions inverses plus précises. Des solutions inverses à un seul dipôle sont obtenues en utilisant la minimisation par méthode du simplexe pour à la fois l’approche conventionnelle et réciproque, chacun avec des versions aux centroïdes et aux sommets. Encore une fois, les simulations numériques sont effectuées sur un modèle à trois sphères concentriques pour des dipôles radiaux et tangentiels d’excentricité variable. La précision des solutions inverses des deux approches est comparée pour les deux conductivités différentes du crâne, et leurs sensibilités relatives aux erreurs de conductivité du crâne et au bruit sont évaluées. Tandis que l’approche conventionnelle aux sommets donne les solutions directes les plus précises pour une conductivité du crâne supposément plus réaliste, les deux approches, conventionnelle et réciproque, produisent de grandes erreurs dans les potentiels du cuir chevelu pour des dipôles très excentriques. Les approches réciproques produisent le moins de variations en précision des solutions directes pour différentes valeurs de conductivité du crâne. En termes de solutions inverses pour un seul dipôle, les approches conventionnelle et réciproque sont de précision semblable. Les erreurs de localisation sont petites, même pour des dipôles très excentriques qui produisent des grandes erreurs dans les potentiels du cuir chevelu, à cause de la nature non linéaire des solutions inverses pour un dipôle. Les deux approches se sont démontrées également robustes aux erreurs de conductivité du crâne quand du bruit est présent. Finalement, un modèle plus réaliste de la tête est obtenu en utilisant des images par resonace magnétique (IRM) à partir desquelles les surfaces du cuir chevelu, du crâne et du cerveau/liquide céphalorachidien (LCR) sont extraites. Les deux approches sont validées sur ce type de modèle en utilisant des véritables potentiels évoqués somatosensoriels enregistrés à la suite de stimulation du nerf médian chez des sujets sains. La précision des solutions inverses pour les approches conventionnelle et réciproque et leurs variantes, en les comparant à des sites anatomiques connus sur IRM, est encore une fois évaluée pour les deux conductivités différentes du crâne. Leurs avantages et inconvénients incluant leurs exigences informatiques sont également évalués. Encore une fois, les approches conventionnelle et réciproque produisent des petites erreurs de position dipolaire. En effet, les erreurs de position pour des solutions inverses à un seul dipôle sont robustes de manière inhérente au manque de précision dans les solutions directes, mais dépendent de l’activité superposée d’autres sources neurales. Contrairement aux attentes, les approches réciproques n’améliorent pas la précision des positions dipolaires comparativement aux approches conventionnelles. Cependant, des exigences informatiques réduites en temps et en espace sont les avantages principaux des approches réciproques. Ce type de localisation est potentiellement utile dans la planification d’interventions neurochirurgicales, par exemple, chez des patients souffrant d’épilepsie focale réfractaire qui ont souvent déjà fait un EEG et IRM.

Relevância:

60.00% 60.00%

Publicador:

Resumo:

Progress in functional neuroimaging of the brain increasingly relies on the integration of data from complementary imaging modalities in order to improve spatiotemporal resolution and interpretability. However, the usefulness of merely statistical combinations is limited, since neural signal sources differ between modalities and are related non-trivially. We demonstrate here that a mean field model of brain activity can simultaneously predict EEG and fMRI BOLD with proper signal generation and expression. Simulations are shown using a realistic head model based on structural MRI, which includes both dense short-range background connectivity and long-range specific connectivity between brain regions. The distribution of modeled neural masses is comparable to the spatial resolution of fMRI BOLD, and the temporal resolution of the modeled dynamics, importantly including activity conduction, matches the fastest known EEG phenomena. The creation of a cortical mean field model with anatomically sound geometry, extensive connectivity, and proper signal expression is an important first step towards the model-based integration of multimodal neuroimages.