On reconsideration of IT governance structures to govern cloud computing services

There is an increase in the uptake of cloud computing services (CCS). CCS is adopted in the form of a utility, and it incorporates business risks of the service providers and intermediaries. Thus, the adoption of CCS will change the risk profile of an organization. In this situation, organisations need to develop competencies by reconsidering their IT governance structures to achieve a desired level of IT-business alignment and maintain their risk appetite to source business value from CCS. We use the resource-based theories to suggest that collaborative board oversight of CCS, competencies relating to CCS information and financial management, and a CCS-related continuous audit program can contribute to business process performance improvements and overall firm performance. Using survey data, we find evidence of a positive association between these IT governance considerations and business process performance. We also find evidence of positive association between business process performance improvements and overall firm performance. The results suggest that the suggested considerations on IT governance structures can contribute to CCS-related IT-business alignment and lead to anticipated business value from CCS. This study provides guidance to organizations on competencies required to secure business value from CCS.

Atomic Scale Fluctuations Govern Brittle Fracture and Cavitation Behavior in Metallic Glasses

We perform atomistic simulations on the fracture behavior of two typical metallic glasses, one brittle (FeP) and the other ductile (CuZr), and show that brittle fracture in the FeP glass is governed by an intrinsic cavitation mechanism near crack tips in contrast to extensive shear banding in the ductile CuZr glass. We show that a high degree of atomic scale spatial fluctuations in the local properties is the main reason for the observed cavitation behavior in the brittle metallic glass. Our study corroborates with recent experimental observations of nanoscale cavity nucleation found on the brittle fracture surfaces of metallic glasses and provides important insights into the root cause of the ductile versus brittle behavior in such materials.

Dissecting Signaling Pathways That Govern Self-renewal of Rabbit Embryonic Stem Cells

The pluripotency and self-renewal of embryonic stem cells (ESC) are regulated by a variety of cytokines/growth factors with some species differences. We reported previously that rabbit ESC (rESC) are more similar to primate ESC than to mouse ESC. However,

Who has the Right to Govern Online Activity? A Criminal and Civil Point of View

Kohl, U. (2004). Who has the right to govern online activity? A criminal and civil point of view. International Review of Law, Computers & Technology 18 (3), 387-410 RAE2008

4 anys d'atacs incessants a la llengua catalana per part del PP, amb Govern o sense.'4 años de ataques incesantes a la lengua catalana por parte del PP, con Gobierno o sin'.

Resumen tomado de la publicación

El projecte Xarxipèlag : pla del Govern de les Illes Balears per incorporar les noves tecnologies de la informació en la pràctica educativa dels centres docents no universitaris. 'El proyecto Xarxipèlag : plan del Govern de les Illes Balears para incorporar las nuevas tecnologías de la información a la práctica educativa de los centros docentes no universitarios'.

Resumen tomado de la revista

La direcció i el govern dels centres a la LOE.'La dirección y el gobierno de los centros en la LOE'.

Se estudian algunos conceptos en los que la LOE ha supuesto una progresión. También se hace énfasis en otros aspectos no tan positivos. Órganos de gobierno o gestión educativa son temas tratados a lo largo del texto.

Què fem des del Govern de la Generalitat per les famílies? '¿Qué hacemos desde el Gobierno de la Generalitat por las familias?'.

De forma continuada se producen cambios sociales en relación con la estructura y las condiciones económicas, sociales y culturales de las familias. Las administraciones públicas también han de realizar cambios para ayudar a éstas familias.

Direcci?? i govern dels centres educatius

Resumen basado en el de la publicaci??n

Josep Pallach, vist des del Govern Civil de Girona (1967-1976)

Fa dotze anys l'autor d'aquest article va donar a conèixer la documentació dels anys 1944-1946 que, procedent dels arxius governatius i de les presons gironines, feia referència a la vida clandestina i de represaliat del polític i professor Josep Pallach (Figueres 1920-l’Hospitalet de Llobregat 1977), antic militant del Bloc Obrer i Camperol i del Partit Obrer d’Unificació Marxista (POUM). Aquest article del 2005 complementa aquella recerca amb la recuperació d’una documentació similar, relativa al temps final del franquisme i al període inicial de la transició, els quals es corresponen també amb els darrers anys del periple vital del protagonista d’aquestes pàgines

Drawing lines in the sea : the laws that govern traffic on the world’s oceans can be as difficult to shape as water

Since World War II, however, the term has increasingly referred to law enforcement operations, as a means to enforce trade sanctions, to prevent the movement of weapons of mass destruction (WMDs), and particularly in the Caribbean Sea, to prevent the smuggling of illicit drugs. Such ambiguity should allow flexibility when deciding whom should be targeted, as well as allowing states with veto powers in the UN Security Council, which may legitimately ship nuclear weapons and materials, to avoid being targeted as long as they do not export WMDs to rogue states or non-state groups or individuals.2 The ISPS Code was created under the auspices of the International Maritime Organization (IMO) and is part of the 1974 Safety of Life at Sea Convention (SOLAS) concerning the safety of merchant ships.

Order-Disorder Transitions Govern Kinetic Cooperativity and Allostery of Monomeric Human Glucokinase

Glucokinase (GCK) catalyzes the rate-limiting step of glucose catabolism in the pancreas, where it functions as the body's principal glucose sensor. GCK dysfunction leads to several potentially fatal diseases including maturity-onset diabetes of the young type II (MODY-II) and persistent hypoglycemic hyperinsulinemia of infancy (PHHI). GCK maintains glucose homeostasis by displaying a sigmoidal kinetic response to increasing blood glucose levels. This positive cooperativity is unique because the enzyme functions exclusively as a monomer and possesses only a single glucose binding site. Despite nearly a half century of research, the mechanistic basis for GCK's homotropic allostery remains unresolved. Here we explain GCK cooperativity in terms of large-scale, glucose-mediated disorder-order transitions using 17 isotopically labeled isoleucine methyl groups and three tryptophan side chains as sensitive nuclear magnetic resonance (NMR) probes. We find that the small domain of unliganded GCK is intrinsically disordered and samples a broad conformational ensemble. We also demonstrate that small-molecule diabetes therapeutic agents and hyperinsulinemia-associated GCK mutations share a strikingly similar activation mechanism, characterized by a population shift toward a more narrow, well-ordered ensemble resembling the glucose-bound conformation. Our results support a model in which GCK generates its cooperative kinetic response at low glucose concentrations by using a millisecond disorder-order cycle of the small domain as a "time-delay loop," which is bypassed at high glucose concentrations, providing a unique mechanism to allosterically regulate the activity of human GCK under physiological conditions.