History of Richmond Lodge, No. 10, A.F. & A. M. /

Cover titile: History of Richmond Lodge, No. 10 A.F. and A.M., 1790-1909.

History and by-laws of Richmond Royal Arch Chapter No. 3, A.F. & A.M., Richmond, Virginia, with a list of officers and members;

On cover: 1792-1911.

The white apron; a compilation of the history of Occidental Lodge, no. 40, A.F. & A.M., Ottawa, Illinois, with a complete list of members from the date of dispensation, 1845, to October 10, 1906, and a summary of her daughter, Humboldt Lodge, no. 555, A.F. & A.M., working under the jurisdiction of the Grand Lodge of Kentucky, 1839 to 1845. Also a resume of her daughter, St. John's Lodge, no. 13, A.F. & A.M., located at Vermillionville in 1841, and transferred to Pern, Illinois, 1843. Also a synopsis of the introduction of freemasonry into America and the first lodges in Illinois.

Mode of access: Internet.

Masonic discourse delivered by request of Loge Francaise, no. 53, A.F. & A.M., on Sunday, December 24th, 1871, by John E. Edwards, chaplain.

"Religious, masonic discourse."

Epidemiology of uveitis in children over a 10-year period.

OBJECTIVES: The aim of the present study is to investigate the demographics, aetiologies, complications, treatments and visual outcomes in paediatric uveitis patients in the French-speaking part of Switzerland. METHODS: Chart review of all patients diagnosed with uveitis before the age of 16 years, presenting to two tertiary referral centres (uveitis and paediatric rheumatology clinics) in Lausanne, Switzerland, between 2000 and 2009. RESULTS: Seventy-nine children (37 girls) were identified, 62 living in Switzerland, 15 in Europe and 2 in North Africa. Median age at first symptoms was 9.0 years (range 1.5-15.8 years), with a median follow-up time of 1.8 years (0-8 years). Both eyes were involved in 51 patients (64.6%). The course was acute in 30.4%, chronic in 60.8% and recurrent in 8.9%. Anterior uveitis occurred in 39.2%, intermediate in 32.9%, posterior in 22.8% and panuveitis in 5.1%. The three main diagnoses were idiopathic uveitis (34.2%), JIA-related uveitis (22.8%) and toxoplasmic retinochoroiditis (15.2%). During the last follow-up visit, the visual acuity (VA) was ≥8/10 in 72% of all eyes with a measurable VA. Cataract (8%), ocular hypertension/glaucoma (8%) and macular fibrosis (4%) were the three most common severe complications. Systemic steroids were given to 56% and biological agents to 24% of patients with inflammatory uveitis. CONCLUSIONS: Uveitis in children can be a devastating disease. A strict classification of aetiologies and a tight collaboration between paediatric rheumatologists and ophthalmologists are important to ensure early control of ocular inflammation and improve long-term visual prognosis.

Toronto Lodge of Perfection

On April 25, 1878 at an informal meeting of members of the Toronto Chapter of Rose Croix a petition was presented for a warrant for a Lodge of Perfection. The Toronto Lodge of Perfection of the Scottish Rite Masonry in the Valley of Toronto held its inaugural meeting in Toronto, Ont. on May 22 1878 with support and approval of the Supreme Council for Canada. From time to time, the name of the chapter was also known as the Toronto Grand Lodge of Perfection, but was dropped permanently in 1884. The group continues to meet today in Toronto, Ontario.

Translational neuroprotection research in glaucoma: a review of definitions and principles

The maintenance of vision, through prevention and attenuation of neuronal injury in glaucoma, forms the basis of current clinical practice. Currently, the reduction of intraocular pressure is the only proven method to achieve these goals. Although this strategy enjoys considerable success, some patients progress to blindness; hence, additional management options are highly desirable. Several terms describing treatment modalities of neuronal diseases with potential applicability to glaucoma are used in the literature, including neuroprotection, neurorecovery, neurorescue and neuroregeneration. These phenomena have not been defined within a coherent framework. Here, we suggest a set of definitions, postulates and principles to form a foundation for the successful translation of novel glaucoma therapies from the laboratory to the clinic.

Estimation of axon counts in a rat model of glaucoma: comparison of fixed-pattern sampling with targeted sampling

Full axon counting of optic nerve cross-sections represents the most accurate method to quantify axonal damage, but such analysis is very labour intensive. Recently, a new method has been developed, termed targeted sampling, which combines the salient features of a grading scheme with axon counting. Preliminary findings revealed the method compared favourably with random sampling. The aim of the current study was to advance our understanding of the effect of sampling patterns on axon counts by comparing estimated axon counts from targeted sampling with those obtained from fixed-pattern sampling in a large collection of optic nerves with different severities of axonal injury.

Proyecto constructivo para el acondicionamiento del trazado ferroviario en desuso Madrid-Burgos (Tramo San Mamés-Braojos) para su uso como vía verde.

El Programa de Vías Verdes, de la Fundación de los Ferrocarriles Españoles, propone reutilizar los trazados ferroviarios en desuso; como infraestructuras para caminantes, ciclistas, etc. en condiciones de máxima accesibilidad, seguridad y facilidad. Se propone la adecuación como vía verde de los 10.1 km del tramo San Mamés - Braojos de la Sierra (ambos, en Madrid) de la línea ferroviaria Madrid-Burgos cerrada al servicio en 2011. Esta vía atraviesa los municipios de Navarredonda y San Mamés, Villavieja del Lozoya, Gascones y Braojos de la Sierra, todos en la Comunidad de Madrid. Se plantea esta Vía Verde al objeto de potenciar el ecoturismo en la zona

Ars quatuor coronatorum, being the transactions of the Quatuor coronati lodge no. 2076, London.

Mode of access: Internet.

Sorafenib for the treatment of metastatic thyroid cancer patients.

Segons resultats de fases II amb inhibidors tirosina quinasa i el coneixement de les alteracions moleculars de la carcinogènesis tiroïdal, es va dissenyar un estudi retrospectiu de pacients amb càncer de tiroide metastàtic tractats amb sorafenib. S’analitzaren la taxa de respostes, toxicitat, supervivència i la correlació amb els marcadors tumorals de 34 pacients. Segons subtipus histològic, la taxa de respostes va ser 47% en medul•lars, 19% en diferenciats i 33% en anaplàsics. La mitjana de supervivència-lliure-de-progressió va ser 13.5, 10.5 i 4.4 mesos, respectivament. Es va observar correlació significativa entre la reducció dels nivells de marcador tumoral i la resposta. El perfil de toxicitat va ser favorable.

Comparación de los resultados a largo plazo de cirugía y valvuloplastia percutánea para el tratamiento de la estenosis pulmonar aislada.

Se compararon en una población de 211 pacientes con estenosis pulmonar reparada el tratamiento quirúrgico y percutáneo, las complicaciones y reintervenciones a largo plazo y predictores de las mismas. Los pacientes del grupo quirúrgico se intervinieron de forma más precoz, presentaban una anatomía más compleja, más síntomas y peor perfil hemodinámico. El tiempo medio de seguimiento global fue de 22 ± 10,21 años y no se observaron diferencias significativas en cuanto a la necesidad de reintervención. La aparición de complicaciones no difirió entre los dos grupos. Una mayor edad en el momento de la cirugía, defectos congénitos asociados y síntomas prequirúrgicos fueron factores de riesgo para padecer complicaciones mayores. Por lo tanto, a pesar de que la evolución a largo plazo es globalmente buena, la aparición de complicaciones y la necesidad de reintervención a lo largo del seguimiento no es despreciable y sigue reportándose a pesar de la introducción de la valvuloplastia percutánea como tratamiento de primera línea.

¿Favorece la publicación en abierto el impacto de los artículos científicos? Un estudio empírico en el ámbito de la medicina intensiva

Peer-reviewed

Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study): A 12-month, randomized, controlled, double-masked, multicenter phase II study

The expression of vascular endothelial growth factor (VEGF) is elevated in diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants. We investigated the safety and efficacy of ranibizumab in DME involving the foveal center.