Explosionsfeste Transportbehälter – mehr Sicherheit für das Transportwesen

Weltweit ist eine Zunahme terroristischer Aktivitäten zu verzeichnen, sodass allgemein damit gerechnet werden muss, dass auch das zivile Verkehrs- und Transportwesen ein bevorzugtes Ziel terroristischer Anschläge darstellt. Mehrfach wurden schon Sprengkörper in Transportmittel des öffentlichen und zivilen Personen- aber auch Güterverkehrs eingeschleust, um die Bevölkerung durch materielle Zerstörung und massive Personenschäden einzuschüchtern und zu beängstigen. Daher ist eine Anpassung der sich derzeit im Einsatz befindlichen Transportbehälter an die geänderten Rahmenbedingungen unerlässlich, um auch den Schutz vor Sprengkörpern, die gemeinsam mit dem Handgepäck in Luft-, Land- und Wasserfahrzeuge eingeschleust werden, zu gewährleisten.

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 177 - Dankesschreiben wegen der Zusendung der Dissertation

u.a.: Dissertation Schopenhauers; Über die vierfache Wurzel des Satzes vom zureichenden Grunde; Analyse über den geistigen Zustand der Studentenschaft in Deutschland; Habilitation Schopenhauers; Doktorprüfung; August Wilhelm Schlegel; Prof. Schweins, Dekan der philosophischen Fakultät Heidelberg; Zahn;

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 142 - Glückwunschschreiben anlässlich des 68. Geburtstages

u.a.: Redaktion eines Artikels zur Philosophie Schopenhauers im Frankfurter Museum; Fehlende Wertschätzung Schopenhauers; Blätter für literarische Unterhaltung; Preisausgabe von der Fakultät Leipzig; Julius Frauenstädt; Johanna Schopenhauer;

Gases e ruídos em edificações para suínos: aplicação das normas NR-15, CIGR e ACGIH

Swine production represents an important segment of Brazilian economy, and the possibility of increasing production is eminent mainly if considered the low pork consumption when compared to other meat and the consumption of other countries. The increasing need in the international market demands show that in a near future the commercial barriers will be based on welfare, in the protection of the environment as well as in the worker's legislation. Little knowledge is available in the subject of worker's standards in the environmental agents in rural activities as well as the air quality under Brazilian conditions. The objectives of this research were to apply the main used standards related to noise and gases and to estimate occupational risk using measurements of noise level, hydrogen sulfide, methane and oxygen in swine housing, in piglet's nursery and finishing. The results showed that the continuous noise level were below the one found in the standards, however there were observed differences (P < 0.05) in relation to the noise level measured in piglet's nursing cages and in semi-slatted floor. The respective concentrations of hydrogen sulfide and methane were less than 1 ppm and less than 0,1% by volume, which was lower than the recommended limits in NR-15, CIGR and ACGIH. The oxygen level was 21% in average.

Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase

Farnesol (FOH) is a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, a catabolite of the cholesterol biosynthetic pathway. These isoprenoids inhibit proliferation and induce apoptosis. It has been shown previously that FOH triggers morphological features characteristic of apoptosis in the filamentous fungus Aspergillus nidulans. Here, we investigate which pathways are influenced through FOH by examining the transcriptional profile of A. nidulans exposed to this isoprenoid. We observed decreased mRNA abundance of several genes involved in RNA processing and modification, transcription, translation, ribosomal structure and biogenesis, amino acid transport and metabolism, and ergosterol biosynthesis. We also observed increased mRNA expression of genes encoding a number of mitochondrial proteins and characterized in detail one of them, the aifA, encoding the Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. The Delta aifA mutant is more sensitive to FOH (about 8.0% and 0% survival when exposed to 10 and 100 mu M FOH respectively) than the wild type (about 97% and 3% survival when exposed to 10 and 100 mu M FOH respectively). These results suggest that AifA is possibly important for decreasing the effects of FOH and reactive oxygen species. Furthermore, we showed an involvement of autophagy and protein kinase C in A. nidulans FOH-induced apoptosis.

The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance

Farnesol (FOH) is a nonsterol isoprenold produced by dephosphorylanon of farnesyl pyrophosphate a catabolite of the cholesterol biosynthetic pathway These isoprenoids inhibit proliferation and induce apoptosis Here we show that Aspergillus nidulans MA encoding the apoptosis-Inducing factor (AIF)-like mitochondrial oxidoreductase plays a role in the function of the mitochondrial Complex I Additionally we demonstrated that ndeA B and ndiA encode external and internal alternative NADH dehydrogenases respectively that have a function in FOH resistance When exposed to FOH the Delta aifA and Delta ndeA strains have increased ROS production while Delta ndeB Delta ndeA Delta ndeB and Andul mutant strains showed the same ROS accumulation than in the absence of FOH We observed several compensatory mechanisms affecting the differential survival of these mutants to FOH (C) 2010 Elsevier Inc All rights reserved

Recensão de: Shimon Peres, Un temps pour la guerre, un temps pour la paix, trad. Magda Bigotte de Figueiredo, Lisboa, Publicações Dom Quixote, 2004, 142 pp.

Revista Lusófona de Ciências Sociais

Detection of Change in Fluorescence Between Reactive Cyan and the Yellow Fluorophores Using a-SiC:H Multilayer Transducers

The transducer consists of a semiconductor device based on two stacked -i-n heterostructures that were designed to detect the emissions of the fluorescence resonance energy transfer between fluorophores in the cyan (470 nm) and yellow (588 nm) range of the spectrum. This research represents a preliminary study on the use of such wavelength-sensitive devices as photodetectors for this kind of application. The device was characterized through optoelectronic measurements concerning spectral response measurements under different electrical and optical biasing conditions. To simulate the fluorescence resonance energy transfer (FRET) pairs, a chromatic time-dependent combination of cyan and yellow wavelengths was applied to the device. The generated photocurrent was measured under reverse and forward bias to read out the output photocurrent signal. A different wavelength-biasing light was also superimposed. Results show that under reverse bias, the photocurrent signal presents four separate levels, each one assigned to the different wavelength combinations of the FRET pairs. If a blue background is superimposed, the yellow channel is enhanced and the cyan suppressed, while under red irradiation, the opposite behavior occurs. So, under suitable biasing light, the transducer is able to detect separately the cyan and yellow fluorescence pairs. An electrical model, supported by a numerical simulation, supports the transduction mechanism of the device.

Synthesis and properties of Co-doped titanate nanotubes and their optical sensitization with methylene blue

Agência Financiadora - Fundação para a Ciência e Tecnologia - PTDC/CTM NAN/113021/2009

Inactivación reversible de la NR: Aislamiento y caracterización de la proteína inactivante de hojas de avena

La fosforilación reversible de proteínas, catalizadas por protein-kinasas y protein fosfatasas es uno de los principales modos de regulación metabólica en plantas. Entre las enzimas cuya actividad es modulada por procesos de fosforilación reversible está la nitrato reductasa (NR) de plantas superiores. Estos procesos son los responsables de la inactivación reversible de la NR de hojas, observada in vivo, durante la transición luz-oscuridad, correspondiendo la forma fosforilada a la enzima inactiva y la defosforilada a la máxima actividad. Se ha demostrado que la inactivación por fosforilación de la NR sólo es detectada en presencia de cationes divalentes libres y de una proteína inactivante (FI), que ha sido aislada y caracterizada en dictiledóneas. Los datos disponibles permiten suponer que esta proteína existe también en monocotiledóneas, pero hasta el momento esto no ha sido comprobado. El objeto del trabajo es determinar si este FI es de ocurrencia generalizada, por lo que se tratará de aislarlo y caracterizarlo en hojas de avena, donde también fue demostrada la inactivación por fosforilación de la NR.

Autoimmunthyreoiditis vom Typ Hashimoto im Kindesalter : klinische und biochemische Befunde zum Zeitpunkt der Diagnose bei 142 Patienten aus einem Zentrum

Magdeburg, Univ., Medizin. Fakultät, Diss., 2009