995 resultados para Falguière, Jean-Alexandre-Joseph, 1831-1900.
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On cover: La Plume, numéro exceptionnel consacré a A. Falguière.
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Signatur des Originals: S 36/G03668
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Signatur des Originals: S 36/G03803
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Collection : Théâtre classique des français ; T. XII-XVI
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With the immense growth in the number of available protein structures, fast and accurate structure comparison has been essential. We propose an efficient method for structure comparison, based on a structural alphabet. Protein Blocks (PBs) is a widely used structural alphabet with 16 pentapeptide conformations that can fairly approximate a complete protein chain. Thus a 3D structure can be translated into a 1D sequence of PBs. With a simple Needleman-Wunsch approach and a raw PB substitution matrix, PB-based structural alignments were better than many popular methods. iPBA web server presents an improved alignment approach using (i) specialized PB Substitution Matrices (SM) and (ii) anchor-based alignment methodology. With these developments, the quality of similar to 88% of alignments was improved. iPBA alignments were also better than DALI, MUSTANG and GANGSTA(+) in > 80% of the cases. The webserver is designed to for both pairwise comparisons and database searches. Outputs are given as sequence alignment and superposed 3D structures displayed using PyMol and Jmol. A local alignment option for detecting subs-structural similarity is also embedded. As a fast and efficient `sequence-based' structure comparison tool, we believe that it will be quite useful to the scientific community. iPBA can be accessed at http://www.dsimb.inserm.fr/dsimb_tools/ipba/.
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[Vente (Art). 1779-12-01 - 1779-12-29. Paris]
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Mode of access: Internet.
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Mode of access: Internet.
Jean de Bry (1760-1835 [i.e. 1834]); le Congrés de Rastatt; une préfecture sous le premier empire; /
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Mode of access: Internet.
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Contiene: t. 1, t. 2, t. 3, t. 5.
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Mode of access: Internet.
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Mode of access: Internet.