Inside Child Study Center, Chapman College, Orange, California

Children and teachers sitting around a table inside the Child Study Center, Chapman College, Orange, California.

Chapman College Child Study Center, Orange, California

Staff and children seated outside the Chapman College Child Study Center, North Center Street, Orange, California.

Chapman College Child Study Center, Orange, California

View of the front exterior of the Chapman College Child Study Center, North Center Street, Orange, California, 1979.

Chapman College Child Study Center play area

Chapman College Child Study Center playground, with three children on a tire swing.

Chapman College Child Study Center

Garage and play area at the Chapman College Child Study Center, Orange, California.

Chapman College Child Study Center play area, Orange, California

Chapman College Child Study Center play area, Orange, California

Professor Fred Smoller, Child Study Center, Chapman College, Orange, California

Professor Fred Smoller, Child Study Center, Chapman College, Orange, California, June, 1990.

Chapman College Child Study Center

Chapman College Child Study Center, North Center Street, Orange, California, June, 1990.

Child Study Center, Chapman College, Orange, California

Professor Fred Smoller, Child Study Center, Chapman College, Orange, California, June, 1990.

Chapman College Child Study Center

Renovation work on the Chapman College Child Study Center, Orange, California, ca. 1990.

Chapman College Child Study Center

Renovation work on the Chapman College Child Study Center, Orange, California, ca. 1990.

Chapman College Child Study Center play area

Playground area for the Chapman College Child Study Center, Orange, California, June, 1990.

Chapman College Child Study Center

Renovation work on the Chapman College Child Study Center building, Orange, California, 1990.

Early infection and asymptomatic spread of hepatitis A virus in a public child care center in Rio de Janeiro, Brazil: should attending children under two years of age be vaccinated?

A cross-sectional study was conducted in order to identify hepatitis A virus (HAV) serological markers in 418 individuals (mean age, 16.4 years; range, 1 month-80 years) at a public child care center in Rio de Janeiro, Brazil, as well as to analyze risk factors and determine circulating genotypes. Serum samples were tested using an enzyme immunoassay. Reverse transcription polymerase chain reaction (RT-PCR) was used to detect and characterize HAV RNA, and sequencing was performed. Anti-HAV antibodies and IgM anti-HAV antibodies were detected, respectively, in 89.5% (374/418) and 10.5% (44/418) of the individuals tested. Acute HAV infection in children was independently correlated with crawling (p < 0.05). In 56.8% (25/44) of the IgM anti-HAV-positive individuals and in 33.3% (5/15) of the IgM anti-HAV-negative individuals presenting clinical symptoms, HAV RNA was detected. Phylogenetic analysis revealed co-circulation of subgenotypes IA and IB in 93.3% (28/30) of the amplified samples. In present study, we verify that 79% (30/38) of children IgM anti-HAV-positive were asymptomatic. In child care centers, this asymptomatic spread is a more serious problem, promoting the infection of young children, who rarely show signs of infection. Therefore, vaccinating children below the age of two might prevent the asymptomatic spread of hepatitis A.

Investigation of the Iowa Department of Human Services’ Oversight of a Child Care Center, September 11 , 2013

Over a three-month period in 2010, our office received three complaints alleging the Department of Human Services (DHS) was lax in its oversight of a licensed child care center. It was alleged that the DHS did not sanction the child care center in any meaningful way after finding several violations associated with children engaging in sexual behavior with each other at the center. This involved the Child Development Center (CDC) in Des Moines, which is owned and operated by Children and Families of Iowa (CFI).