Non-invasive, quantitative analysis of drug mixtures in containers using spatially offset Raman spectroscopy (SORS) and multivariate statistical analysis

In this paper, spatially offset Raman spectroscopy (SORS) is demonstrated for non-invasively investigating the composition of drug mixtures inside an opaque plastic container. The mixtures consisted of three components including a target drug (acetaminophen or phenylephrine hydrochloride) and two diluents (glucose and caffeine). The target drug concentrations ranged from 5% to 100%. After conducting SORS analysis to ascertain the Raman spectra of the concealed mixtures, principal component analysis (PCA) was performed on the SORS spectra to reveal trends within the data. Partial least squares (PLS) regression was used to construct models that predicted the concentration of each target drug, in the presence of the other two diluents. The PLS models were able to predict the concentration of acetaminophen in the validation samples with a root-mean-square error of prediction (RMSEP) of 3.8% and the concentration of phenylephrine hydrochloride with an RMSEP of 4.6%. This work demonstrates the potential of SORS, used in conjunction with multivariate statistical techniques, to perform non-invasive, quantitative analysis on mixtures inside opaque containers. This has applications for pharmaceutical analysis, such as monitoring the degradation of pharmaceutical products on the shelf, in forensic investigations of counterfeit drugs, and for the analysis of illicit drug mixtures which may contain multiple components.

Hydrocarbon plasma for treatment of biodegradable food containers

A newly developed middle-frequency (2 MHz) inductively coupled plasma (ICP) source with internal oscillating current is used to treat biodegradable food packaging surfaces. Initially hydrophilic packaging turns to hydrophobic after being processed by ICP plasma. The investigation of optical emission from hydrocarbon radicals in the Ar/ CH4 plasma helps us to understand the property of the hydrophobicity of the surfaces. © 2008 IEEE.

Jugglers Arts Space Containers

The design and installation for the Jugglers Arts Space Containers was an invited commission by Jugglers Arts Space for the Containveral Festival at Northshore Hamilton (EDQ). The community festival involved a suite of custom designed and fitted shipping containers for the use by retailers and arts groups alike, focusing upon re-use and low cost design fabrication approaches. Containerval, inspired from shipping container projects such as Sean Goodsell's 'Future Shack' (1985-2001)and Buchan Group's Re:Start Mall, Christchurch (2011), celebrated design testing and exploration of found and recyclable materials to plan and enrich an otherwise severe hardstand area formally attached to Portside docks. The design proposed use of 4 containers, planned to focus on both the interior displays and external in-between spaces, for live performance of Jugglers Arts Space artists. Experimentation of recyclable materials such as onion bags and plastic milk bottles, informed the development of innovative low-cost canopies which sutured the containers together. The Containerval Festival contributed to the now highly successful 'Eat Street Markets' at Hamilton Northshore.

An autonomous mobile manipulator for collecting sample containers

In this work we present an autonomous mobile ma- nipulator that is used to collect sample containers in an unknown environment. The manipulator is part of a team of heterogeneous mobile robots that are to search and identify sample containers in an unknown environment. A map of the environment along with possible positions of sample containers are shared between the robots in the team by using a cloud-based communication interface. To grasp a container with its manipulator arm the robot has to place itself in a position suitable for the manipulation task. This optimal base placement pose is selected by querying a precomputed inverse reachability database.

Artisanal containers and transportation for smoke-dried fish in Nigeria

The packaging containers and means of transportation for Nigerian smoke-dried fish from harvesting all through the post-harvest chain were described. Sacks, paper cartons, wooden rackets, cane and bamboo baskets were predominantly used packaging containers. Means of transportation ranged from wheelbarrows, motorcycle, lorries, to pick-up vehicles and trucks. The major area of improvement is seen in packaging at the wholesale level. To overcome the constraints within the system, both the public and private sectors must provide effective services that benefit fishermen, processors, wholesalers, retailers, organisation and other key participants that make the work. Suggestions for reducing post harvest losses and improving the efficiency of the existing distribution system, based on the various need of the stake holders and the socio-cultural settings of the application were proffered

Studies on transportation of fish. Pt. 1. Packaging of frozen fish in insulated containers

The paper deals with certain technological aspects of transportation of fish. Frozen fish packed in thermocole insulated plywood box (tea chests) and transported has been found to remain in good condition, for 3 to 4 days. Fish reaching the destination in a thawed state can be stored in crushed ice for a further period of 2-3 days. The effect of initial temperature of frozen fish on the storage life, the maximum storage period for different types of frozen fish packed in the insulated container and the changes in chemical and organoleptic qualities of different varieties of fish under condition of transport are also discussed.

Analysis of multivariable Smith predictors using MATLAB Containers

Containers are structured m-files which allow `data' and `methods' to be stored persistently. Containers have a user-defined class structure, so that one can have several Containers of the same class, all structurally similar, and there is a mechanism for interaction with Containers in the style of database transactions. The use of MATLAB Containers to analyze multivariable Smith predictors is discussed.

Transportation of fish - 3. Biochemical changes in fish during transportation in insulated containers

The changes in the biochemistry of different varieties of iced fish during transportation in thermocole lined second hand tea chests from Veraval to Bombay and Delhi are discussed. The moisture increased for all the varieties except for eel and hilsa at Bombay. TMAN and TVN increased in all cases. Maximum increase of TMAN and TVN was observed in seer fish.

Comparative study of traditional and improved containers for transportation of fresh fish

Traditional bamboo basket and expanded polystyrene insulated plywood box (second hand tea-chest) were compared for transportation of iced marine, fresh water and brackish water fishes from Kakinada to Madras by rail. Quality of fish at dispatching and receiving centres was assessed by organoleptic, total volatile nitrogen (TVN) and total bacterial count (TBC) tests. Based on the results obtained and the prices fetched, the traditional bamboo basket apart from being cheaper was found to be as good as expanded polystyrene insulated plywood box for short distance transportation of iced fish involving less than 24 hours journey.