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High-performance parallel systems for data-intensive computing

Thesis (Ph.D.)--University of Washington, 2016-08

DAVID HOMEOMORPHISMS VIA CARLESON BOXES

We construct a family of examples of increasing homeomorphisms of the real line whose local quasi-symmetric distortion blows up almost everywhere, which nevertheless can be realized as the boundary values of David homeomorphisms of the upper half-plane. The construction of such David extensions uses Carleson boxes.

Co-morbidity between alcohol, tobacco and cannabis use: reply to David Fergusson

No abstract

Gene complementation of airway epithelium in the cystic fibrosis mouse is necessary and sufficient to correct the pathogen clearance and inflammatory abnormalities

Increasingly, cystic fibrosis (CF) is regarded as an inflammatory disorder where the response of the lung to Pseudomonas aeruginosa is exaggerated as a consequence of processes mediated by the product of the CF gene, CFTR. Of importance to any gene-replacement strategy for treatment of CF is the identification of the cell type(s) within the lung milieu that need to be corrected and an indication whether this is sufficient to restore a normal inflammatory response and bacterial clearance. We generated G551D CF mice transgenically expressing the human CFTR gene in two tissue compartments previously demonstrated to mediate a CFTR-dependent inflammatory response: lung epithelium and alveolar macrophages. Following chronic pulmonary infection with P. aeruginosa, CF mice with epithelial-expressed but not macrophage-specific CFTR showed an improvement in pathogen clearance and inflammatory markers compared with control CF animals. Additionally, these data indicate the general role for epithelial cell-mediated events in the response of the lung to bacterial pathogens and the importance of CFTR in mediating these processes.

Occurrence of immature Culicoides molestus (Skuse) (Diptera : Ceratopogonidae) in relation to habitat characteristics

Analysis of beach sites on the Gold Coast, Australia, found that 14 physical and chemical habitat characteristics differed significantly between sites where numerous immatures of the canal biting midge, Culicoides molestus (Skuse), were found and sites where no midge immatures occurred. Five of the chemical factors found to reliably distinguish C. molestus habitat are major components of seawater, while another, electrical conductivity, is related to the concentration of seawater components. Calcium was the only one of the six primary components of seawater that was not a statistically significant correlate of C. molestus habitation by sand analysis. It is likely that a causative variable in occurrence of immatures is the concentration of seawater present in canals, because larvae are found where seawater component concentration is low in relation to uninhabited sites of similar appearance.

Do dois ao múltiplo na terra do um: a experiência antropológica de David Maybury-Lewis

Este artigo busca uma compreensão da trajetória do antropólogo britânico, radicado nos EUA, David Maybury-Lewis. Aborda aspectos de sua formação intelectual, que envolveram uma longa pesquisa entre os Xavante e um estudo comparativo sobre os povos de língua jê e bororo do Brasil Central. Maybury-Lewis é um nome central para o desenvolvimento de um "americanismo tropical". Entre suas contribuições etnográficas e teóricas, pode-se citar a elaboração de um modelo analítico jê e bororo, a renovação dos estudos de parentesco e a reflexão sobre a relação entre povos indígenas e o Estado. Um tema parece, com efeito, permear a sua obra: o das organizações dualistas. Não por menos, esse foi o motivo de um longo debate com a obra de Lévi-Strauss, que será aqui destacado.