A narrative of the proceedings in America, of the Society called Quakers, in the case of Hannah Barnard. Intended as a sequel to An Appeal to the Society of Friends.

Mode of access: Internet.

Some tracts relating to the controversy between Hannah Barnard and the Society of Friends : wherein the primitive Christian principles of the said Society are presented to the public.

Preface, by Christicola.--A summary of Hannah Barnard's faith, written by herself.--Remarks occasioned by a paper, called, a summary of Hannah Barnard's faith, [by] a lover of the truth as it is in Jesus.--Hannah Barnard's vindication of her summary, &c.--Some animadversions upon Hannah Barnard's defence of her summary, &c., [by] Christicola.

Embroidered facts :

Reproduction of original in British Library, London.

Lives of celebrated women:

Added t.p., engr.

Hannah Karminski speaking with Mrs. Neuhaus; Conference of Juedisches Frauenbundes; Duerkheim Portraits Groups Women

Digital Image

Memoirs of the life and correspondence of Mrs. Hannah More /

Mode of access: Internet.

Memoirs of the life and correspondence of Mrs. Hannah More /

Mode of access: Internet.

Edward Barnard, or, Merit exalted : containing the history of the Edgerton family /

Engraved frontispiece signed: Cook sc. [Thomas Cook?]; dated: April 29, 1797.

A memoir of Miss Hannah Adams,

"Notices in continuation", by Mrs. Hannah F. Lee: p. [45]-110.

The works of Mrs. Cowley; dramas and poems.

v.1 Dramas.--v.2. Dramas.--v.3. Poems.

Ethyl-eicosapentaenoic acid in first-episode psychosis : a 1H-MRS study

Ethyl-eicosapentaenoic acid (E-EPA) is an omega-3 fatty acid that has been used in a range of neuropsychiatric conditions with some benefits. However, its mechanism of action is unknown. Here, we investigate its effects on in vivo brain metabolism in first-episode psychosis (FEP). Proton magnetic resonance spectroscopy at 3 T was performed in the temporal lobes of 24 FEP patients before and after 12 weeks of treatment in the context of a larger double-blind, placebo-controlled E-EPA augmentation study. Treatment group effects for glutathione (F1,12=6.1, p=0.03), and a hemisphere-by-group interaction for glutamine/glutamate (F1,20=4.4, p=0.049) were found. Glutathione increased bilaterally and glutamate/glutamine increased in the left hemisphere following E-EPA administration. Improvement in negative symptoms correlated with metabolic brain changes, particularly glutathione (r=-0.57). These results suggest that E-EPA augmentation alters glutathione availability and modulates the glutamine/glutamate cycle in early psychosis, with some of the metabolic brain changes being correlated with negative symptom improvement. Larger confirmatory studies of these postulated metabolic brain effects of E-EPA are warranted.

A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis

Schizophrenia is associated with significant brain abnormalities, including changes in brain metabolites as measured by proton magnetic resonance spectroscopy (MRS). What remains unclear is the extent to which these changes are a consequence of the emergence of psychotic disorders or the result of treatment with antipsychotic medication. We assessed 34 patients with first episode psychosis (15 antipsychotic naïve) and 19 age- and gender-matched controls using short-echo MRS in the medial temporal lobe bilaterally. Overall, there were no differences in any metabolite, regardless of treatment status. However, when the analysis was limited to patients with a diagnosis of schizophrenia, schizophreniform or schizoaffective disorder, significant elevations of creatine/phosphocreatine (Cr/PCr) and myo-inositol (mI) were found in the treated group. These data indicate a relative absence of temporal lobe metabolic abnormalities in first episode psychosis, but suggest that some treatment-related changes in mI might be apparent in patients with schizophrenia-spectrum diagnoses. Seemingly illness-related Cr/PCr elevations were also specific to the diagnosis of schizophrenia-spectrum disorder and seem worthy of future study.

Mrs Klein

Described as ‘ferociously sharp’, Crossbow Production’s Mrs Klein is about the formidable psychoanalyst Melanie Klein whose ruthlessly ‘objective’ case studies of her children won her acclaim as both an inspiring and appalling woman. Did her ‘study’ drive her son to suicide? Starring Therese Collie (La Boite), Louise Brehmer (QTC, La Boite) and Caroline Beck (New York Broadway credits). Directed by Dr Christian Heim. Live classical music and sharp wit combine to make this a memorable production.