Resolución No. 179

Servicios registrales

Análise da resistência à fadiga de tubos de aço API 5CT N80 Tipo Q soldados via processo de indução magnética de alta frequência (HFIW)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Chromosomal abnormalities in couples with recurrent first trimester abortions

PURPOSE: To investigate the prevalence of chromosomal abnormalities in couples with two or more recurrent first trimester miscarriages of unknown cause. METHODS: The study was conducted on 151 women and 94 partners who had an obstetrical history of two or more consecutive first trimester abortions (1-12 weeks of gestation). The controls were 100 healthy women without a history of pregnancy loss. Chromosomal analysis was performed on peripheral blood lymphocytes cultured for 72 hours, using Trypsin-Giemsa (GTG) banding. In all cases, at least 30 metaphases were analyzed and 2 karyotypes were prepared, using light microscopy. The statistical analysis was performed using the Student t-test for normally distributed data and the Mann-Whitney test for non-parametric data. The Kruskal-Wallis test or Analysis of Variance was used to compare the mean values between three or more groups. The software used was Statistical Package for the Social Sciences (SPSS), version 17.0. RESULTS: The frequency of chromosomal abnormalities in women with recurrent miscarriages was 7.3%, including 4.7% with X-chromosome mosaicism, 2% with reciprocal translocations and 0.6% with Robertsonian translocations. A total of 2.1% of the partners of women with recurrent miscarriages had chromosomal abnormalities, including 1% with X-chromosome mosaicism and 1% with inversions. Among the controls, 1% had mosaicism. CONCLUSION: An association between chromosomal abnormalities and recurrent miscarriage in the first trimester of pregnancy (OR=7.7; 95%CI 1.2--170.5) was observed in the present study. Etiologic identification of genetic factors represents important clinical information for genetic counseling and orientation of the couple about the risk for future pregnancies and decreases the number of investigations needed to elucidate the possible causes of miscarriages.

Influência do tamanho e da forma da semente de milho sobre o desenvolvimento da planta e a produtividade de grãos

Due to the small and the round seeds represent a rather high proportion of an ear, this experiment viewed to study the effects of those factors on seed germinative performance in the field as well as on the plant traits related to grain yield. Six treatment combinations replicated five times were sown in Votuporanga/SP on 08/22/2008. Flat shaped (C) and round shaped (R) seeds were made to go through flat round and oblong hole screens which resulted in the following treatments: 1. C1: seeds remaining on the top of a 23/64 '' round hole screen, 2. C2G: 21/64 '', 3. C3M: 17/64 '' or 16/64 '', 4. R2GM: medium length seeds remaining on the top of 13 x 3/4 '' oblong hole screen, 5. R3M: medium length seeds remaining on a 12 x 3/4 '' (from 1 to 2 mm bigger than R3), and 6. R3: 12 x 3/4 ''. The soil of the experimental area was submitted to a no-till cultivation system and the rows were set 0.6 m apart from one another. Fifteen days after emergence (DAE), the plants were thinned to a population of 66,000 plants/ha. Harvest took place 115 DAE and the mean yield was of 12,498 kg ha(-1). Based on the results it was concluded that only the initial growth of the plants is significantly affected by seed size. Plant traits such as plant height, ear insertion height, culm diameter, number of grains per year, grain weight and size as well as grain yield evaluated 40 or more DAE are not significantly affected by seed size or seed shape.

Caracterização microestrutural de junta soldada com arco submerso e análise da propagação de trincas em um tubo de aço API X 70

In this work a study of an API 5L X70 steel, which is used in the manufacture of oil and gas pipelines, has been made. This class of steel show high strength and ductility values, and has been increasingly studied due the growing demand of oil and natural gas, which in consequence, increases the needing of new pipelines to transport them. The material studied has been directly taken from a tube provided by TenarisConfab, and a special attention has been given to the fatigue crack growth rate study, which proved that a crack will grow at different rates according to the tube position where it is growing

Análise da resistência à fadiga de tubos de aço API 5CT N80 Tipo Q soldados via processo de indução magnética de alta frequência (HFIW)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Vascular access in patients with peripheral arterial disease undergoing TAVI: the hostile registry

BACKGROUND The optimal access route in patients with severe peripheral artery disease (PAD) undergoing TAVI remains undetermined. OBJECTIVE To compare clinical outcomes with transfemoral access (TFA), transthoracic access (TTA), and non-thoracic alternative access (TAA) in TAVI patients with severe PAD. METHODS Patients with PAD and hostile femoral access (TFA impossible, or possible only after percutaneous treatment) undergoing TAVI at 28 international centers were included in this registry. The primary endpoint was the propensity-adjusted risk of 30-day major adverse events (MAE) defined as the composite of all-cause mortality, stroke/transitory ischemic attack (TIA) or main access site-related VARC 3 major vascular complications. Outcomes were also stratified according to the severity of PAD using a novel risk score (Hostile score). RESULTS Among the 1,707 patients included in the registry, 518 (30.3%) underwent TAVI with TFA after percutaneous treatment, 642 (37.6%) with TTA, and 547 (32.0%) with TAA (mostly transaxillary). Compared with TTA, both TFA (adjusted HR=0.58, 95%CI 0.45-0.75) and TAA (adjusted HR=0.60, 95%CI 0.47-0.78) were associated with lower 30-day rates of MAE, driven by fewer access site-related complications. Composite risks at 1 year were also lower with TFA and TAA compared with TTA. TFA compared with TAA was associated with lower 1-year risks of stroke/TIA (adjusted HR=0.49, 95%CI 0.24-0.98), a finding confined to patients with low Hostile scores (Pinteraction=0.049). CONCLUSIONS Among patients with PAD undergoing TAVI, both TFA and TAA were associated with lower 30-day and 1-year rates of MAE compared with TTA, but 1-year stroke/TIA rates were higher with TAA compared with TFA.

Atributos químicos de um latossolo bruno sob sistema plantio direto em função da estratégia de adubação e do método de amostragem de solo

Adubo em sulco de semeadura nem sempre aumenta a produtividade de culturas anuais, contudo aumenta a variabilidade química das áreas agrícolas, especialmente dos nutrientes P e K. Essa variabilidade é maior no sistema plantio direto por não haver homogeneização da camada superficial pelo preparo mecânico. Neste trabalho, avaliou-se, em um Latossolo Bruno, por longo período sob plantio direto, o efeito de estratégias de aplicação de adubo sobre a distribuição de alguns atributos químicos do solo em profundidade após três e seis anos do início do experimento e sobre a variação desses atributos em função de dois métodos de coleta de amostras de solo, com e sem inclusão da linha de semeadura. Foram feitos dez tratamentos, nove contemplando fontes de P (fosfato natural e superfosfato triplo - STP), mecanismos sulcadores (disco duplo e haste), formas (sulco e superfície) e épocas (inverno e verão) de aplicação de adubo de semeadura e um tratamento controle, sem adubação. Os atributos químicos do solo foram maiores nas camadas superficiais e sua distribuição em profundidade, com exceção do P, não foi alterada pelas estratégias de adubação. O teor de P foi menor na profundidade de 0-5 cm com o uso contínuo, por mais de três anos, do sulcador tipo haste e com a ausência de adubação. Com a inclusão da linha de semeadura na amostragem, foram observados maiores teores de K e Ca e maiores valores de CTC. Os métodos de coleta de amostras de solo, com e sem inclusão da linha de semeadura, e as profundidades de coleta 0-10 e 0-20 cm foram semelhantes quanto à interpretação dos resultados das análises para recomendação de adubação e calagem para áreas sob sistema plantio direto, por longo período.

Capacidade máxima de adsorção de fósforo e constante de energia em Latossolo Bruno em razão de diferentes ajustes do modelo Langmuir

A capacidade máxima de adsorção de fósforo (CMAP) é um parâmetro bastante útil para caracterizar a capacidade de adsorção de fósforo (P) do solo e, por isso, o modelo de Langmuir, que possibilita essa estimativa, é bastante difundido. Porém, se o ajuste da equação for realizado por modelos não lineares ou linearizados, ou se forem escolhidos modelos de região única ou múltiplas, nem sempre os valores estimados da CMAP e da constante de energia de ligação (k) são semelhantes. O objetivo deste trabalho foi avaliar o efeito do uso de diferentes métodos de ajuste do modelo de Langmuir sobre os valores estimados de CMAP e k. Para isso, utilizouse um único solo de alta capacidade de adsorção de P, o qual foi misturado a quantidades crescentes de areia lavada, construindo-se sistemas com capacidades de sorção crescentes, mas com a fase sólida constituída da mesma mineralogia. Foi utilizado solo do horizonte B de um Latossolo Bruno com 800 g kg-1 de argila, o qual foi misturado com areia em quantidades para obterem-se solos artificiais com 0, 200, 400, 600 e 800 g kg-1 de argila. Esses solos artificiais foram incubados por 30 dias com calcário para elevar o pH(H2O) até 6,0 e, após, foram secos em estufa e peneirados. Foram realizadas as isotermas de adsorção e os dados ajustados pelo modelo de Langmuir, usando os seguintes métodos: NLin - não linear com região única; L-1R - linearização com região única; L-2RG - linearização com duas regiões, ajuste gráfico; L-3RG - linearização com três regiões, ajuste gráfico; L-2RE linerização com duas regiões, ajuste estatístico. Os resultados evidenciaram que todos os métodos utilizados estimaram valores de CMAP proporcionais ao teor de argila dos solos e poderiam ser usados para caracterizar os solos. Contudo, quando utilizados ajustes com mais de uma região de adsorção, os valores da CMAP para a última região foram sensivelmente superiores àqueles observados após a incubação do solo com doses de P em um teste adicional. Isso indica que a CMAP da última região deve ser evitada como caracterizadora da capacidade de adsorção do solo. Conforme era esperado, os valores de k foram proporcionais aos teores de argila do solo na primeira (ou única) região dos modelos linearizados; contudo, não seguiram essa tendência no modelo não linear, recomendando-se cautela na interpretação da constante k ajustada por modelos não lineares.

Prospecto de una eneida apostólica, ó epopeya, que celebra la predicación del V. apóstol del occidente P. Fr. Antonio Margil de Jesús : intitulada Margileida...

UANL

¿Pluralismo o colonialidad médica? Un estudio alrededor del cáncer en diferentes sistemas médicos colombianos

En esta investigación se realiza un análisis del tipo de relaciones que se establecen entre la medicina alopática y la medicina indígena yagecera en el escenario urbano de Bogotá. Para ello, toma distancia de los estudios ya realizados sobre este tema en el campo de la antropología a partir de dos aspectos: en primer lugar, busca acercarse a esta relación a partir de las trayectorias profesionales de un conjunto de médicos (tanto indígenas como alopáticos); en segundo lugar, se aproxima a estas relaciones a partir de una enfermedad particular: el cáncer.

Don Antonio Domínguez Ortiz, académico de la Real Academia de la Historia.

El artículo forma parte de un monográfico dedicado a Don Antonio Domínguez Ortiz

Impaired Incretin Secretion And Pancreatic Dysfunction With Older Age And Diabetes.

To estimate the impact of aging and diabetes on insulin sensitivity, beta-cell function, adipocytokines, and incretin production. Hyperglycemic clamps, arginine tests and meal tolerance tests were performed in 50 non-obese subjects to measure insulin sensitivity (IS) and insulin secretion as well as plasma levels of glucagon, GLP-1 and GIP. Patients with diabetes and healthy control subjects were divided into the following groups: middle-aged type 2 diabetes (MA-DM), aged Type 2 diabetes (A-DM) and middle-aged or aged subjects with normal glucose tolerance (MA-NGT or A-NGT). IS, as determined by the homeostasis model assessment, glucose infusion rate, and oral glucose insulin sensitivity, was reduced in the aged and DM groups compared with MA-NGT, but it was similar in the MA-DM and A-DM groups. Insulinogenic index, first and second phase insulin secretion and the disposition indices, but not insulin response to arginine, were reduced in the aged and DM groups. Postprandial glucagon production was higher in MA-DM compared to MA-NGT. Whereas the GLP-1 production was reduced in A-DM, no differences between groups were observed in GIP production. In non-obese subjects, diabetes and aging impair insulin sensitivity. Insulin production is reduced by aging, and diabetes exacerbates this condition. Aging associated defects superimposed diabetic physiopathology, particularly regarding GLP-1 production. On the other hand, the glucose-independent secretion of insulin was preserved. Knowledge of the complex relationship between aging and diabetes could support the development of physiopathological and pharmacological based therapies.

Neck Circumference As A New Anthropometric Indicator For Prediction Of Insulin Resistance And Components Of Metabolic Syndrome In Adolescents: Brazilian Metabolic Syndrome Study.

To evaluate the correlation between neck circumference and insulin resistance and components of metabolic syndrome in adolescents with different adiposity levels and pubertal stages, as well as to determine the usefulness of neck circumference to predict insulin resistance in adolescents. Cross-sectional study with 388 adolescents of both genders from ten to 19 years old. The adolescents underwent anthropometric and body composition assessment, including neck and waist circumferences, and biochemical evaluation. The pubertal stage was obtained by self-assessment, and the blood pressure, by auscultation. Insulin resistance was evaluated by the Homeostasis Model Assessment-Insulin Resistance. The correlation between two variables was evaluated by partial correlation coefficient adjusted for the percentage of body fat and pubertal stage. The performance of neck circumference to identify insulin resistance was tested by Receiver Operating Characteristic Curve. After the adjustment for percentage body fat and pubertal stage, neck circumference correlated with waist circumference, blood pressure, triglycerides and markers of insulin resistance in both genders. The results showed that the neck circumference is a useful tool for the detection of insulin resistance and changes in the indicators of metabolic syndrome in adolescents. The easiness of application and low cost of this measure may allow its use in Public Health services.