Index libro[rum] in hoc volumi[n]e co[n]te[n]to[rum] domini Symphoriani Champerij physici lugdun[ensi] : Libelli duo, primus De medicine claris scriptoribus in quinq[ue] partitus tractatus , secundus De legu[m] diuinaru[m] conditoribus una cu[m] impugnatione fecte machometice qua[m] arabes alchoranu[m] vocant ... ; Dyalogus d[omi]ni Symphoriani Cha[m]perij [et] Sebastiani Copini mollissonie[m]sis in legem machometicam ; Eiusdem d[omi]ni Symphoriani De corporu[m] animorumque morbis eorumdeque remediis opusculu[m] in duos partitu[m] libellos : primus introductiuus est in practica[m] Galeni, secundus Egritudinu[m] animoru[m] curatiuus ; Eua[n]gelice christianeq[ue] religionis excriptis ge[n]tiliu[m] [et] poetaru[m] [et] philosopho[rum] validissimis argume[n]tis co[m]probatio ; Eiusde[m] d[omi]ni Symphoriani Aphorismi siue collectiones medicinales ... Alexa[n]dri aphrodisei greci de febribus ; Opera parua Hippocratis nouiter de greco in latinum traducta lib. vii ; Epistole queda[m] ad ip[so]m[et] ... Symphorianu[m] cha[m]perium.

Ind. Aur.,

Luciani Samosatensis Saturnalia, Cronosolon id est Saturnalium legum lator, Epistolae Saturnales, De luctu, Abdicatus, Icaromenippus seu Hypernephelus, Toxaris siue amicitia, Alexa[n]der seu Pseudoma[n]tis, Gallus seu Somnium, Timon seu Misanthropus, Pro tyra[n]nicida declamatio, Erasmi declamatio Lucinianicae respondens, De iis qui mercede conducti degunt, Dialogi XVIII, Hercules Gallicus, Eunuchus seu Pamphilus, De sacrificiis, Conuiuium seu Lapithae, De astrologia, Des. Erasmo Roterod. interprete : Aliquot item ex eode[m] commentarii, Thoma Moro interprete, quos in calce huius libri numeratos reperies ...

CCBE S. XVI,

Habentur hoc volumine haec Theodoro Gaza interprete, Aristotelis De natura animalium lib. ix ; eiusdem De partibus animalium lib. iiii ; eiusdem De generatione animalium lib. v. Theophrasti De historia plantarum lib. ix et decimi principium duntaxat ; eiusdem De causis plantarum lib vi. Aristotelis problemata ... Alexa[n]dri Aphrodisiensis p[ro]blemata duobus libris no[n] unqua[m] ante i[m]pressa ...

"Problematum Aristotelis ..." con portadilla propia en h. [205] r.

Flow cytometry as a tool in the evaluation of blood leukocyte function in Chelonia mydas (Linnaeus, 1758) (Testudines, Cheloniidae)

Chelonia mydas is a sea turtle that feeds and nests on the Brazilian coast and a disease called fibropapillomatosis is a threat to this species. Because of this, it is extremely necessary to determine a methodology that would enable the analysis of blood leukocyte function in these sea turtles. In order to achieve this aim, blood samples were collected from C. mydas with or without fibropapillomas captured on the São Paulo north coast. Blood samples were placed in tubes containing sodium heparin and were transported under refrigeration to the laboratory in sterile RPMI 1640 cell culture medium. Leukocytes were separated by density gradient using Ficoll-PaqueTM Plus, Amershan Biociences®. The following stimuli were applied in the assessment of leukocyte function: Phorbol Miristate-Acetate (PMA) for oxidative burst activity evaluation and Zymosan A (Saccharomyces cerevisiae) Bio Particles®, Alexa Fluor® 594 conjugate for phagocytosis evaluation. Three cell populations were identified: heterophils, monocytes and lymphocytes. Monocytes were the cells responsible for phagocytosis and oxidative burst.

PREVALENCE OF ANTIBODIES TO TRYPANOSOMA CRUZI, LEISHMANIA INFANTUM, ENCEPHALITOZOON CUNICULI, SARCOCYSTIS NEURONA, AND NEOSPORA CANINUM IN CAPYBARA, HYDROCHOERUS HYDROCHAERIS, FROM SAO PAULO STATE, BRAZIL

Little is known about the importance of capybara. Hydrochoerus hydrochaeris, as reservoirs for parasites of zoonotic or veterinary importance. Sera from 63 capybaras, from 6 counties in the state of Sao Paulo, Brazil, were examined for antibodies to Trypanosoma cruel, Leishmania infantum, Encephalitozoon cuniculi. Sarcacystis neurona, and Neospora caninum using an indirect immunofluorescent antibody test. Five (8%) of the 63 capybaras had antibodies to T cruzi epimastigotes. None of the samples from capybara reacted positively with L. infantum promastigotes or with spores of E. cuniculi. Two (3%) of the serum samples were positive for antibodies to S. neurona merozoites, and 2 (3%) of the serum samples were positive for antibodies to N. caninum tachyzoites. A serum sample from 1 capybara was positive for antibodies to both T cruzi and N. caninum. None of the remaining 62 samples reacted with more than 1 parasite.

Serological Survey for Antibodies to Encephalitozoon cuniculi in Ownerless Dogs From Urban Areas of Brazil and Colombia

There are 3 strains of Encephalitozoon cuniculi that occur in mammals. Strain III is associated with clinical disease in dogs, although some can be asymptomatic carriers and excrete spores in their urine. Several cases of human E. cuniculi infection caused by strain III have been observed in immunocompromised patients, indicating that E. cuniculi should be considered a zoonotic agent. Encephalitozoon cuniculi can cause fatal disease in maternally-infected or young dogs. Clinical signs in these animals included blindness, encephalitis, retarded growth rate, and nephritis. Encephalitozoon cuniculi has also been associated with primary renal failure in adult dogs. The present study used the direct agglutination test (DAT, cut-off 1:50) and the indirect fluorescent antibody test (IFAT, cut-off 1:10) to examine the prevalence of antibodies to E. cuniculi in dogs from Brazil and Colombia. Using the DAG, 31 (27.4%) of 113 dogs from Brazil and 47 (18.5%) of 254 dogs from Colombia were seropositive. Nine (14.3%) of 63 dogs from Brazil and IS (35.3%) of the 51 dogs from Colombia were seropositive by indirect immunofluorescent antibody test. These results indicate that dogs from Brazil and Colombia are exposed to E. cuniculi.

CARACTERIZAÇÃO TECNOLÓGICA DE MADEIRAS AMAZÔNICAS PARA A CONSTRUÇÃO PESADA.

O presente trabalho foi desenvolvido com seis (seis) espécies florestais, gitó (Guarea trichilioides),louro-chumbo (Licaria canela),cumarurana (Dypteryx pollyphylla),louro-aritu (Licaria arltu),macucu-fofo (Licania oblongifolia)e melancieira (Alexa grandiflora),oriundas da área da Hidrelétrica de Balbina no município de Presidente Figueiredo-AM, as quais foram submetidas aos ensaios de densidade básica, flexão estática, compressão paralela e perpendicular às fibras, dureza Janka e testes de tratabilidade, alem de levantamentos bibliográficos acerca da durabilidade natural dae mesmas, objetivando uma classificação em categorias de usos finais, tais como: pontes, carrocerias, dormentes e pilares. Os resultados obtidos revelaram que somente a espécie denominada melancieira não apresentou os requisitos exigidos para as utilizações mencionadas.

Treinamento aeróbio não altera pressão arterial de mulheres menopausadas e com síndrome metabólica

FUNDAMENTO: A Hipertensão arterial (HA) é uma condição tanto agravante quanto agravada pela Síndrome Metabólica (SM). A menopausa pode tornar o tratamento da hipertensão mais difícil porque é uma condição que favorece a piora nos componentes da SM. Embora existam evidências de que o treinamento com exercícios físicos reduza a pressão arterial, se as condições da menopausa e da SM afetam os benefícios induzidos pelo exercício é algo ainda não evidenciado. OBJETIVO: Comparar os efeitos do treinamento aeróbio na pressão arterial entre mulheres com SM não menopausadas e menopausadas. MÉTODOS: Foram recrutadas 44 mulheres divididas em quatro grupos experimentais: controle não menopausada (CNM: 39,5 ± 1,1 anos, n = 11); controle menopausada (CM: 54,9 ± 1,7 anos, n = 12); aeróbio não menopausada (ANM: 43,1 ± 2,1 anos, n = 11) e aeróbio menopausada (AM: 52,1 ± 1,6 anos, n = 10). Os grupos de exercício realizaram treinamento aeróbio durante três meses, cinco vezes por semana, com intensidade entre 60% e 70% da frequência cardíaca de reserva. A pressão arterial de repouso e a resposta pressórica clínica após 60 minutos de exercício foram medidas antes e após o período treinamento. O teste de ANOVA de dois fatores foi usado, considerando p < 0,05. RESULTADOS: O programa de treinamento resultou em redução da gordura abdominal, glicemia e melhora do VO2 máx. Em comparação aos valores pré-intervenção, Pressão Arterial Sistólica (PAS) e Pressão Arterial Diastólica (PAD) não se alteraram após o treinamento nos grupos CNM, CM, ANM e AM (p > 0,05). CONCLUSÃO: Três meses de treinamento aeróbio melhora componentes da SM, mas não altera a pressão arterial de repouso, nem a resposta pressórica aguda após uma sessão de exercício aeróbio em mulheres com SM.

Interaction between primary and secondary sporocysts of Schistosoma mansoni and the internal defence system of Biomphalaria resistant and susceptible to the parasite

The outcome of the interaction between Biomphalaria and Schistosoma mansoni depends on the response of the host internal defence system (IDS) and the escape mechanisms of the parasite. The aim of this study was to evaluate the responsiveness of the IDS (haemocytes and soluble haemolymph factors) of resistant and susceptible Biomphalaria tenagophila lineages and Biomphalaria glabrata lineages in the presence of in vitro-transformed primary sporocysts and secondary sporocysts obtained from infected B. glabrata. To do this, we assayed the cellular adhesion index (CAI), analysed viability/mortality, used fluorescent markers to evaluate the tegumental damage and transplanted secondary sporocysts. B. tenagophila Taim was more effective against primary and secondary sporocystes than the susceptible lineage and B. glabrata. Compared with secondary sporocysts exposed to B. tenagophila, primary sporocysts showed a higher CAI, a greater percentage of dead sporocysts and were labelled by lectin from Glycine max and Alexa-Fluor 488 fluorescent probes at a higher rate than the secondary sporocysts. However, the two B. tenagophila lineages showed no cercarial shedding after inoculation with secondary sporocysts. Our hypothesis that secondary sporocysts can escape the B. tenagophila IDS cannot be confirmed by the transplantation experiments. These data suggest that there are additional mechanisms involved in the lower susceptibilty of B. tenagophila to S. mansoni infection.

Neutrality as a Twofold Concept

Under the circumstances of pluralism people often claim that the state ought to be neutral towards its citizens’ conceptions of the good life. However, what it means for the state to be neutral is often unclear. This is partly because there are different conceptions of neutrality and partly because what neutrality entails depends largely on the context in which neutrality is demanded. This paper discusses three different conceptions of neutrality – neutrality of impact, neutrality as equality of opportunity and justificatory neutrality – and analyses the strengths and weaknesses of the different conceptions in different contexts. It suggests that there are two common elements of neutrality in all its exemplifications: a) an element of “hands-off” and b) an element of equal treatment. It therefore argues that while justificatory neutrality is necessary for the state to be neutral it is not sufficient and claims that while conceptions of the good must not enter thejustificationof state regulations, they must be taken into consideration when deliberating theimplementation of these regulations.

What is the Web?

An introductory lecture on Web Science, taking a kind of devils advocate position by suggesting that the Web is a piece of runaway technology that escaped from research labs prematurely.

Información y consumo de drogas : la TV como factor de riesgo en niños escolares.

El artículo pertenece a una sección de la revista dedicada a investigación. - Resumen tomado parcialmente de la revista.