An analysis of alcohol rehabilitation efforts. Analytic study 6.

National Highway Traffic Safety Administration, Washington, D.C.

An analysis of alcohol rehabilitation efforts.

National Highway Traffic Safety Administration, Washington, D.C.

Analysis of alcohol rehabilitation activities. Section II - volume 6. Analytic study number 6. Final report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Analysis of alcohol rehabilitation efforts. Analytical study no. 6. 1973.

National Highway Traffic Safety Administration, Washington, D.C.

Summary report on alcohol rehabilitation.

Mode of access: Internet.

An analysis of alcohol rehabilitation efforts in Columbus, Georgia from January, 1972 - December, 1974. Analytic study 6.

National Highway Traffic Safety Administration, Washington, D.C.

Analytical Study #6: an analysis of alcohol rehabilitation efforts. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

SD: ASAP analytic study no. 5/6 - 1977: an analysis of alcohol rehabilitation efforts. Final report.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Adherence with naltrexone prescription advice in hospital outpatient alcohol rehabilitation programme

Background: The anti-craving drug, naltrexone, is used as a pharmacotherapeutic adjunct in the treatment of alcohol dependence. In addictive disorders, compliance issues remain central. There are limited data on compliance with naltrexone treatment regimens within formalized rehabilitation programs and even less data that identifies factors that have an impact on this. Objective: To study patient adherence to naltrexone medication regimens and examine whether patients' reported pre-treatment alcohol use, dependence severity and measures of psychological health are predictive of medication compliance. Method: Fifty outpatients meeting DSM IV criteria for alcohol dependence enrolled in 12-week rehabilitation programme. This included cognitive behavioural therapy (CBT) and naltrexone, 50 mg orally daily. Measures included: pharmacy prescription pick-up including number of tablets dispensed, programme attendance and patient pre-treatment alcohol use variables. Measures of psychological health included somatic symptoms, anxiety, social dysfunction and depression as measured by the General Health Questionnaire (GHQ-28). Results: Classifying the sample into compliant (greater than or equal to 90% medication pick-up) and less compliant groups, 66% of subjects were naltrexone-compliant. Pre-treatment alcohol use variables were not predictive of compliance. Although social dysfunction and depression tended towards poorer prescription filling, measures of psychological distress (GHQ-28) did not identify factors predictive of medication non-compliance. One patient withdrew from treatment because of naltrexone-induced dysphoria. Conclusion: Patients with alcohol dependence demonstrated high levels of anti-craving medication compliance, good rehabilitation programme participation and favourable outcomes. Naltrexone was well tolerated. Medication compliance in this study group compared well with those of other hospital populations with chronic disorders. Factors predictive of anti-craving medication compliance in alcohol dependence require further study.

Diagnosis, referral, and rehabilitation within the Fairfax Alcohol Action Project, 1976 analytic study no. 5/6. Volume I.

National Highway Traffic Safety Administration, Office of Driver and Pedestrian Programs, Washington, D.C.

Diagnosis, referral and rehabilitation within the Fairfax Alcohol Safety Action Project, 1976: the Fairfax short term rehabilitation study. Analytic study # 5/6. Volume II. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

San Antonio Alcohol Safety Action Project - analytic study no. 5-6: analysis of PDE and rehabilitation. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

San Antonio Alcohol Safety Action Project - analytical study no. 6: final analysis of rehabilitation - 1972 through 1974. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Bone mineral density of rat femurs after hindlimb unloading and different physical rehabilitation programs

Bone weakening can occur due to the absence of load on the skeleton or even short periods of decreased physical activity. Therefore, musculoskeletal diseases that involve temporary immobilization by casts, inactivity or tension increases the risk of fractures. Physical activity is the most studied procedure both to prevent damage and to restore bone structure. The present study aimed at evaluating, by bone densitometry on rat femurs, the influence of hindlimb unloading and later running activity on treadmill or free movement. Sixty-four Wistar rats were used, aged 65 days with a mean corporal mass of 316.11g, randomly divided into eight experimental groups: group 1, the suspended control with seven animals under hindlimb unloading regimen for 28 days, then euthanized; groups 2 and 3, the trained suspended comprising of 7 and five animals, respectively, subjected to hindlimb unloading for 28 days, followed by treadmill exercise for 28 days (group 2) or 56 days (group 3), then euthanized; groups 4 and 5, designated free suspended, comprised of 7 animals each under hindlimb unloading regimen for 28 days followed by free activity in cages for 28 days (group 4) or 56 days (group 5), then euthanized; groups 6, 7 and 8, negative controls, each with 8 animals allowed to free activity in cages and euthanized at the ages of 93, 121 and 149 days, respectively. Bone mineral density (BMD) of the left femur was analyzed by bone densitometry. Unloading by tail-suspension decreased BMD while treadmill training and free activity in cages promoted its recovery in a similar way and over time.