O competidor interespecífico pode alterar a agressividade intraespecífica? um estudo com caranguejos do gênero Uca

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The role of adrenal steroidogenesis in arterial hypertension

Adrenal aldosterone production, the major regulator of salt and water retention, is discussed with respect to hypertensive diseases. Physiological aldosterone production is tightly regulated, either stimulated or inhibited, in the adrenal zona glomerulosa by both circulating factors and/or by locally derived endothelial factors. Arterial hypertension caused by volume overload is the leading clinical symptom indicating increased mineralocorticoid hormones. Excessive aldosterone production is seen in adenomatous disease of the adrenals. The balance between stimulatory/proliferative and antagonistic signaling is disturbed by expression of altered receptor subtypes in the adenomas. Increased aldosterone production without a detectable adenoma is the most frequent form of primary aldosteronism. Both increased sensitivity to agonistic signals and activating polymorphisms within the aldosterone synthase gene (CYP11B2) have been associated with excessive aldosterone production. 17alpha-Hydroxylase deficiency and glucocorticoidremediable aldosteronism can also cause excessive mineralocorticoid synthesis. In contrast, the severe form of pregnancy-induced hypertension, preeclampsia, is characterized by a compromised volume expansion in the presence of inappropriately low aldosterone levels. Initial evidence suggests that compromised CYP11B2 is causative, and that administration of NaCl lowered blood pressure in pregnant patients with low aldosterone availability due to a loss of function.

Security considerations for wireless carrier agonistic bio-monitoring systems

Advances in information and communications technology has led to a significant advances in noncontact portable devices capable of monitoring vital signals of patients. These wearable and implantable bio-monitoring systems allow collections of wearable sensors to be constructed as a Body Area Network (BAN) to record biological data for a subject. Such systems can be used to improve the quality of life and treatment outcomes for patients. One of the main uses for a bio-monitoring system is to record biological data values from a subject and provide them to a doctor or other medical professional. However, wearable bio-monitoring systems raise unique security considerations. In this paper, we discuss some of the security considerations that have arisen in our work around communications agnostic bio-monitoring, and how we have addressed these concerns. Furthermore, the issues related to the identifying and trusting sender and receiver entities are discussed.