645 resultados para 944
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Contient : 1° « La Raison pour quoy l'en dit chascun jour VII. heures » ; 2° Paraphrase du Pater ; 3° Paraphrase du Credo ; 4° « Ly Traitiers qui aprent à faire vraye et certaine confession selon les.VII. pechés mortelz, et les branches qui descendent d'iceux pechiés » ; 5° « Les.X. Commandemens » ; 6° « Le Livre de Bestiaire », traduction du Phisiologus par « PIERRE » ; 7° « Traictié de moralités » ; 8° Guide des confesseurs
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Receipt (copy) for the amount received from Burton and Bro. for the sum of $944.00 paid in full for stumpage on berths 192 and 198. It is signed by S.D. Woodruff, May 24, 1878.
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Abschrift vorhanden
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Includes indexes.
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"March 1966."
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"April 1979."
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"April 1966."
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Purpose: To search for novel biomarkers for early diagnosis of cervical cancer, as well as novel therapeutic target for cervical cancer. Methods: A total of 96 cervical tissue specimens were collected from patients in the Second Affiliated Hospital of Zhengzhou University, out of which 10 were normal control. The remaining specimens (86) were cervical cancer specimens and were divided into 4 groups (A - D) based on tumor-biomarker levels of CA125 and SCC. Quantitative real-time polymerase chain reaction technology (qRT-PCR) was used to detect the expressions of miRNA-143, miRNA-34A, miRNA-944, miRNA-101 and miRNA-218 in the cervical cancer tissues. Results: The levels of CA125 (U/mL) and SCC (ug/L) expressed in normal control group and groups A - D were 11.75 and 0.73 (n = 10), 382 and 2.72 (n = 25), 912.9 and 3.93 (n = 21), 1675 and 5.87 (n = 29), and 2120 and 6.66 (n = 11), respectively. Furthermore, qRT-PCR results showed that the expressions of miRNA-944 and miRNA-218 in cervical cancer tissues were markedly up-regulated compared to normal control tissues (p < 0.01). In contrast, the expression level of miRNA-143, miRNA-34A, and miRNA-101 were significantly decreased (p < 0.01). Conclusion: The biomarkers, miRNA-143, miRNA-34A, miRNA-944, miRNA-101 and miRNA-218, can be considered novel for early diagnosis of cervical cancer.