994 resultados para 591
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New studies are giving ecologists some hope of controlling red lionfish, a voracious predator that has invaded the Atlantic.
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A multifaceted investigation was undertaken to develop recommendations for methods to stabilize granular road shoulders with the goal of mitigating edge ruts. Included was reconnaissance of problematic shoulder locations, a laboratory study to develop a method to test for changes in granular material stability when stabilizing agents are used, and the construction of three sets of test sections under traffic at locations with problematic granular shoulders. Full results of this investigation are included in this report and its appendices. This report also presents conclusions and recommendations based on the study results.
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Luettelo Kansalliskirjastossa olevan Kosti Linnan arkiston sisällöstä
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The Knox-Wise Family Papers includes a land grant issued to John Knox in 1768; diaries written by Dr. John Knox [1792-1859] covering the 1840s and 1850s; James N. Knox [1806-1880] covering 1859-1880; and William D. Knox [1847-1928] covering 1869-1928; indentures, deeds, receipts, court summonses and other papers of Hugh Knox [1757-1821], sheriff and justice of the peace in Chester County, South Carolina (ca. 1780s and 1790s); correspondence of James N. Knox, correspondence, and other professional papers of Dr. John Knox; correspondence, and other papers of William D. Knox, Superintendent of Education in Chester County from 1896-1928. Papers of various other members of the Knox and Wise families including Hugh Boyd Knox [1814-1886], Robert Knox [1796-1879], Sally Knox Wallace [1803-1901], Alexander Walker Wise, and Emmie R. Knox [1885-1969]; family histories of the Knox, Wise, Dunlap, Gaston, and Wilks families; church histories, photographs, and newspaper clippings. Also included are three published volumes of the United Confederate Veterans Minutes of the 21st (1911) and 25th (1915) Annual Meeting and Reunion; and the minutes of the annual reunion of the South Carolina Division of the United Confederate Veterans (1921-1927).
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To study whether protein kinase C (PKC) isoforms can interact with protein-tyrosine-phosphatases (PTPs) which are connected to the insulin signaling pathway, we co-overexpressed PKC isoforms together with insulin receptor, docking proteins, and the PTPs SHP1 and SHP2 in human embryonic kidney (HEK) 293 cells. After phorbol ester induced activation of PKC isoforms alpha, beta 1, beta 2, and eta, we could show a defined gel mobility shift of SHP2, indicating phosphorylation on serine/threonine residues. This phosphorylation was not dependent on insulin receptor or insulin receptor substrate-1 (IRS-1) overexpression and did not occur for the closely related phosphatase SHP1. Furthermore, PKC phosphorylation of SHP2 was completely blocked by the PKC inhibitor bisindolylmaleimide and was not detectable when SHP2 was co-overexpressed with kinase negative mutants of PKC beta 1 and -beta 2. The phosphorylation also occurred on endogenous SHP2 in Chinese hamster ovary (CHO) cells stably overexpressing PKC beta 2. Using point mutants of SHP2, we identified serine residues 576 and 591 as phosphorylation sites for PKC. However, no change of phosphatase activity by TPA treatment was detected in an in vitro assay. In summary, SHP2 is phosphorylated on serine residues 576 and 591 by PKC isoforms alpha, beta 1, beta 2, and eta.
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u.a.: Auseinandersetzung mit Johann Wolfgang von Goethe;
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Amerikanische Presse, Carl Heinzen, Politische Bemerkungen
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4 Briefe zwischen Max Horkheimer und Nicholas Jory; 3 Briefe zwischen Nicholas Jory und Frederick Pollock, 1956; 1 Brief von Frederick Pollock an die First National City Bank (New York), 27.04.1956; 1 Brief von dem Grand Hotel & Kurhaus (Bad Tarasp) an den "Gast", März 1956; 1 Brief von Franz Ollig an Frederick Pollock, 31.01.1956; 1 Brief von Erna Schroeter an Emmy Henne, 14.01.1956; 1 Brief von The State Bar of California (San Francisco) an Leo Salon, 21.11.1956; 1 Brief von Frederick Pollock an Hans Moeller, 16.10.1956; 2 Briefe zwischen Frederick Pollock und Frederick J. Wild, 1956; 1 Brief von Frederick Pollock an Alice H. Maier, 19.06.1956; 1 Brief von Frederick Pollock an Leo Löwenthal, 16.06.1956; 1 Brief von dem Hotel "Zum Schützen" (München) an Frederick Pollock, 28.05.1956;