Ciencia 3-6 : laboratorios de ciencias en la escuela infantil.

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Raskaan liikenteen taukopaikat Uudenmaan ELY-keskuksen alueella : Kysynnän ja tarjonnan analyysi sekä mahdollisia yhteistoimintamalleja

Selvityksen tavoitteena oli tuottaa kokonaiskuva raskaan liikenteen taukopaikkojen nykytilanteesta, kehittämistarpeista, kysynnästä ja tarjonnasta Uudenmaan ELY-keskuksen alueella sekä kartoittaa esimerkkejä tauko- ja levähdysalueiden toimintamalleista Suomessa ja muualla. Tavoitteena oli tuottaa tietoa kehittämistoimenpiteiden suuntaamiselle ja eri sidosryhmien välisen yhteistoiminnan kehittämiselle. Selvitys toteutettiin kesäkuun ja joulukuun 2015 välisenä aikana. Hankkeessa toteutettiin taukopaikkojen raskaan liikenteen käyttäjälaskenta ja kapasiteetin inventointi elokuussa 2015. Laskenta suoritettiin sekä päivällä että yöllä. Inventoiduista valtion taukopaikoista on tehty myös levähdysaluekortit, joissa on esitetty taukopaikkojen ominaisuustietoja. Taukopaikkojen kysyntää arvioitiin lisäksi selvittämällä suurimmista kaupungeista etelän suuntaan lähtevien kuljetusten ajo- ja lepoaikojen perusteella määritellyt (4½ h ja 9 h) taukovyöhykkeet Uudenmaan ELY-keskuksen alueella. Taukopaikkojen kysynnän kehittymistä arvioitiin vertailemalla käyttäjälaskennan tuloksia aiemmin tehdyn käyttäjälaskennan tuloksiin. Kysynnän kehittymistä tulevaisuudessa arvioitiin Uudenmaan 4. vaihemaakuntakaavan kehityskuvavaihtoehtoa varten tehdyn liikenne-ennusteen perusteella. Kysynnän ja kehittämismahdollisuuksien (tauko- ja levähdysalueiden ominaisuudet) perusteella valittiin ne taukopaikat, joilla on eniten kehittämistarvetta ja -mahdollisuuksia. Nämä kehittämiskohteet priorisoitiin hankkeessa kehitetyllä priorisointimenetelmällä. Uusien taukopaikkojen likimääräinen tarve laskettiin taukopaikkojen kapasiteetin ja yön keskimääräisen käyttöasteen perusteella. Uusien alueiden tarvetta ja toteuttamismahdollisuuksia arvioitiin olemassa olevien suunnitelmien ja kysynnän perusteella. Raportin viimeisessä luvussa esitetään tutkimustuloksista pääteltyjä jatkotoimenpidetarpeita.

COMP3016 Web Technology - Strand "XML" Lecture 5

Lecture 5: XLink and XPointer Lecture slides and exercises for using XLink and XPointer to link to and control material within an XML database or document.

Estudio económico de la demanda de transporte privado en Santafé de Bogotá

La investigación pretende determinar el impacto de los factores que intervienen en la decisión de compra de automóviles particulares mediante herramientas econométricas de análisis

Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease

Epithelial cells in the human small intestine express meprin, an astacin-like metalloprotease, which accumulates normally at the brush border membrane and in the gut lumen. Therefore, meprin is targeted towards luminal components. In coeliac disease patients, peptides from ingested cereals trigger mucosal inflammation in the small intestine, disrupting epithelial cell differentiation and function. Using in situ hybridisation on duodenal tissue sections, we observed a marked shift of meprin mRNA expression from epithelial cells, the predominant expression site in normal mucosa, to lamina propria leukocytes in coeliac disease. Meprin thereby gains access to the substrate repertoire present beneath the epithelium.

Safety of non-therapeutic atomoxetine exposures - a national poison data system study

AIMS This study's objective is to assess the safety of non-therapeutic atomoxetine exposures reported to the US National Poison Database System (NPDS). METHODS This is a retrospective database study of non-therapeutic single agent ingestions of atomoxetine in children and adults reported to the NPDS between 2002 and 2010. RESULTS A total of 20 032 atomoxetine exposures were reported during the study period, and 12 370 of these were single agent exposures. The median age was 9 years (interquartile range 3, 14), and 7380 were male (59.7%). Of the single agent exposures, 8813 (71.2%) were acute exposures, 3315 (26.8%) were acute-on-chronic, and 166 (1.3%) were chronic. In 10 608 (85.8%) cases, exposure was unintentional, in 1079 (8.7%) suicide attempts, and in 629 (5.1%) cases abuse. Of these cases, 3633 (29.4 %) were managed at health-care facilities. Acute-on-chronic exposure was associated with an increased risk of a suicidal reason for exposure compared with acute ingestions (odds ratio 1.44, 95% confidence interval 1.26-1.65). Most common clinical effects were drowsiness or lethargy (709 cases; 5.7%), tachycardia (555; 4.5%), and nausea (388; 3.1%). Major toxicity was observed in 21 cases (seizures in nine (42.9%), tachycardia in eight (38.1%), coma in six (28.6%), and ventricular dysrhythmia in one case (4.8%)). CONCLUSIONS Non-therapeutic atomoxetine exposures were largely safe, but seizures were rarely observed.

(Table 1) Lithology, mineralogy, and physical properties of Cretaceous cherts and porcellanites at DSDP Hole 56-436

Cretaceous chert and porcellanite recovered at Site 436, east of northern Honshu, Japan, are texturally and mineralogically similar to siliceous rocks of comparable age at Sites 303, 304, and 307 in the northwest Pacific. These rocks probably were formed by impregnation of the associated pelagic clay with locally derived silica from biogenic and perhaps some volcanic debris. Fine horizontal laminations are the only primary sedimentary structures, suggesting minimal reworking and transport. Collapse breccias and incipient chert nodules are diagenetic features related to silicification and compaction of the original sediment. Disordered opal-CT (d[101] = 4.09 Å) and microgranular quartz (crystallinity index < 1.0) are the two common silica minerals present. Some samples show quartz replacing this poorly ordered opal- CT, supporting the notion that opal-CT does not become completely ordered (i.e., d[101] = 4.04 Å) in some cases before being converted to quartz. The present temperature calculated for the depth of the shallowest chert and porcellanite at this site is 30 °C; this may represent the temperature of conversion of opal-CT to quartz. High reflection coefficients (0.29-0.65) calculated for the boundary between chert-porcellanite and clay-claystone support the common observation that chert is a strong seismic reflector in deep-sea sedimentary sections.

Dynamically mechanical and nano-impact (fatigue) analysis of touch screen thin films deposited on polyethylene terephthalate substrate

Nano-scale touch screen thin film have not been thoroughly investigated in terms of dynamic impact analysis under various strain rates. This research is focused on two different thin films, Zinc Oxide (ZnO) film and Indium Tin Oxide (ITO) film, deposited on Polyethylene Terephthalate (PET) substrate for the standard touch screen panels. Dynamic Mechanical Analysis (DMA) was performed on the ZnO film coated PET substrates. Nano-impact (fatigue) testing was performed on ITO film coated PET substrates. Other analysis includes hardness and the elastic modulus measurements, atomic force microscopy (AFM), Fourier Transform Infrared Spectroscopy (FTIR) and the Scanning Electron Microscopy (SEM) of the film surface.
Ten delta of DMA is described as the ratio of loss modulus (viscous properties) and storage modulus (elastic properties) of the material and its peak against time identifies the glass transition temperature (Tg). Thus, in essence the Tg recognizes changes from glassy to rubber state of the material and for our sample ZnO film, Tg was found as 388.3 K. The DMA results also showed that the Ten delta curve for Tg increases monotonically in the viscoelastic state (before Tg) and decreases sharply in the rubber state (after Tg) until recrystallization of ZnO takes place. This led to an interpretation that enhanced ductility can be achieved by negating the strength of the material.
For the nano-impact testing using the ITO coated PET, the damage started with the crack initiation and propagation. The interpretation of the nano-impact results depended on the characteristics of the loading history. Under the nano-impact loading, the surface structure of ITO film suffered from several forms of failure damages that range from deformation to catastrophic failures. It is concluded that in such type of application, the films should have low residual stress to prevent deformation, good adhesive strength, durable and good resistance to wear.

Ms.Ff.F.Stoltze 3. 388 - Brief von Friedrich Stoltze an Alexander Müller

"Dem Gott der Kaufleut und der Diebe"