Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010 : a systematic analysis for the Global Burden of Disease Study 2010

Background Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. The Global Burden of Disease (GBD) studies done in 1990 and 2000 have been the only studies to quantify non-fatal health outcomes across an exhaustive set of disorders at the global and regional level. Neither effort quantified uncertainty in prevalence or years lived with disability (YLDs). Methods Of the 291 diseases and injuries in the GBD cause list, 289 cause disability. For 1160 sequelae of the 289 diseases and injuries, we undertook a systematic analysis of prevalence, incidence, remission, duration, and excess mortality. Sources included published studies, case notification, population-based cancer registries, other disease registries, antenatal clinic serosurveillance, hospital discharge data, ambulatory care data, household surveys, other surveys, and cohort studies. For most sequelae, we used a Bayesian meta-regression method, DisMod-MR, designed to address key limitations in descriptive epidemiological data, including missing data, inconsistency, and large methodological variation between data sources. For some disorders, we used natural history models, geospatial models, back-calculation models (models calculating incidence from population mortality rates and case fatality), or registration completeness models (models adjusting for incomplete registration with health-system access and other covariates). Disability weights for 220 unique health states were used to capture the severity of health loss. YLDs by cause at age, sex, country, and year levels were adjusted for comorbidity with simulation methods. We included uncertainty estimates at all stages of the analysis. Findings Global prevalence for all ages combined in 2010 across the 1160 sequelae ranged from fewer than one case per 1 million people to 350 000 cases per 1 million people. Prevalence and severity of health loss were weakly correlated (correlation coefficient −0·37). In 2010, there were 777 million YLDs from all causes, up from 583 million in 1990. The main contributors to global YLDs were mental and behavioural disorders, musculoskeletal disorders, and diabetes or endocrine diseases. The leading specific causes of YLDs were much the same in 2010 as they were in 1990: low back pain, major depressive disorder, iron-deficiency anaemia, neck pain, chronic obstructive pulmonary disease, anxiety disorders, migraine, diabetes, and falls. Age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010. Regional patterns of the leading causes of YLDs were more similar compared with years of life lost due to premature mortality. Neglected tropical diseases, HIV/AIDS, tuberculosis, malaria, and anaemia were important causes of YLDs in sub-Saharan Africa. Interpretation Rates of YLDs per 100 000 people have remained largely constant over time but rise steadily with age. Population growth and ageing have increased YLD numbers and crude rates over the past two decades. Prevalences of the most common causes of YLDs, such as mental and behavioural disorders and musculoskeletal disorders, have not decreased. Health systems will need to address the needs of the rising numbers of individuals with a range of disorders that largely cause disability but not mortality. Quantification of the burden of non-fatal health outcomes will be crucial to understand how well health systems are responding to these challenges. Effective and affordable strategies to deal with this rising burden are an urgent priority for health systems in most parts of the world. Funding Bill & Melinda Gates Foundation.

Diário da Constituinte [gravação de vídeo] : [programa n. 289]

Para beneficiar os Estados, o Deputado Maurício Nasser (PMDB-PR) propõe emenda que garanta uma indenização para o uso de seus recursos naturais. Para o parlamentar, a União deveria pagar royalties aos Estados. A Comissão de Sistematização votará o Título IV do Substitutivo do relator Bernardo Cabral (PMDB-AM), que trata sobre a organização dos poderes e do sistema de governo: presidencialismo ou parlamentarismo. O substitutivo propõe o parlamentarismo. O Deputado Fernando Santana (PCB-BA) defende o parlamentarismo. O grupo parlamentarista está confiante na vitória dentro da Comissão de Sistematização e no Plenário, como declaram os Deputados Gastone Righi, líder do PTB, e Osvaldo Lima Filho (PMDB-PE). Já os presidencialistas acreditam que podem reverter a situação no Plenário, como declaram os deputados Virgílio Guimarães (PT-MG) e Inocêncio Oliveira (PFL-PE). O mandato do presidente José Sarney será definido após a escolha do sistema de governo. O Deputado César Maia (PFL-RJ) tem proposta aprovada na Comissão de Sistematização que reserva vagas aos deficientes físicos em concursos públicos.

Diário da Constituinte [gravação de vídeo] : [programa n. 289 A]

A Comissão de Sistematização conclui capítulo que trata do Servidor Público. Aprovada emenda do Deputado Antônio Carlos Mendes Thame (PFL-SP) que determina igualdade dos salários dos servidores aposentados e os da ativa, tornando a aposentadoria mais justa e digna. O Deputado Gastone Rich (PTB-SP) aprova emenda em que os representantes dos três poderes tenham salário isonômico e será regulamentado por lei ordinária. A emenda do Deputado Paulo Ramos (PMDB-RJ) que estende aos militares os mesmos benefícios concedidos aos servidores públicos civis foi aprovada na Sistematização. Também foi aprovada a emenda do Deputado Arnaldo Faria de Sá (PTB-SP) em que todos os vencimentos estão sujeitos ao desconto de imposto, e a emenda do Deputado Jorge Hage (PMDB-BA) que garante estabilidade no emprego aos servidores públicos. O Deputado Osmar Leitão (PFL-RJ) defende transferências de alguns impostos aos municípios como, por exemplo, o Imposto de Transmissão Intervivo e IPVA. O Deputado Jovanni Masini (PMDB-PR) enfatiza que a proposta satisfaz por ser descentralizadora e permitirá aos municípios maior autonomia. O Deputado Evaldo Gonçalves (PFL-PB) estima que haverá descentralização de responsabilidades e recursos com a Reforma Tributária.

Jornal da UNESP, 2013, ano XXVII, n. 289

Jornal elaborado pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

Arthur Cornwall Papers - Accession 289

The Arthur Cornwall Papers consist of personal, professional, genealogical and reference files of writer, musician, and historian Arthur Cornwall. The collection contains correspondence, radio scripts, feature articles, genealogical research notes, photographs, scrapbooks, and newspaper clippings. Of particular value are the genealogical files which contain exhaustive research relating to the Cornwall-Cornwell and Colvin families of Chester County. The collection includes genealogical research on many other Chester County families, such as Bennett, Coleman, Feaster, Hardin, Loving, Tims, Wylie, and Yongue. Included are many community histories.

Ms. lat. oct. 289 - Antiquitates Judaicae

Vorbesitzer: Isaak Marcus Jost; alte Signatur: Lib.M.55.N.5;

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 289 - Austausch mit Professor Hugo von Meltzl über die Rezeption von Arthur Schopenhauers Werk

u.a.: Einrichtung eines Schopenhauer Archivs; Kritiker der Lehre Schopenhauers; Julius Frauenstädt; Arthur Schopenhauer; Eugen Dühring;

Ms.Ff.F.Stoltze 3. 289 - Brief von Joseph Schmölder an Friedrich Stoltze

Einladung zu einem Besuch

(Table 1) Age determination of basalts from DSDP Hole 30-289

The Pacific plate has undergone a substantial northward displacement during the late Mesozoic and the Cainozoic. Here we give additional documentation for such motion based on palaeomagnetic measurements of a sequence of sedimentary and basalt samples collected from middle Oligocene to Aptian sections of Deep Sea Drilling Project (DSDP) site 289 (Andrews, 1975; 00° 29.92'S, 158° 30.69'E) drilled on the Ontong Java Plateau.

Planktonic foraminifers in DSDP Holes 30-289 and 33-315A

The work is based on samples from Deep-Sea Drilling in the Pacific Ocean and from natural sections in its continental setting. Species composition of planktonic foraminifera from Maastrichtian sediments of the Pacific and South Atlantic oceans, as well as from marginal seas of Australia and New Zealand and epicontinental basins of the northern hemisphere has been analysed. Two main issues: reconstruction of Maastrichtian climatic zonality, and reconstruction of Maastrichtian paleodepths. Four bipolar climatic zones have been distinguished. According to preservation of planktonic foraminifera and composition of their complexes three levels of dissolution have been identified.