Geographisk charta öfver södra delen af Kexholms län

Mittakaava n. 1:109000; laskettu janamittakaavasta (1 svenska mil = 9,8 cm).

Nieuwe ['t] en vergroote zee-boeck

Hollantilaisen kartanpiirtäjän Theunis (Anthonie) Jacobszin suurikokoinen merikartasto, joka sisältää 68 käsinväritettyä karttaa Pohjanmeren ja Itämeren rannikoilta. Jacobsz kuului kartanpiirtäjäsukuun, ja käytti muista erottuakseen myös lisänimeä "Lootsman". Kyseisen kartaston tästä painoksesta ei tunneta muita kappaleita. A. E. Nordenskiöld oli ostanut kartaston kokoelmaansa Amsterdamista vuonna 1892. Samaan niteeseen on sidottu toinenkin kartasto, Joannes Janssoniuksen DE LICHTENDE COLOMNE OFTE ZEE-SPIEGEL vuodelta 1653, joka kuvaa läntisen Euroopan rannikkoa ja satamia Kanariansaarille asti.

Gib' mir dein Herze

Soitinnus: lauluääni, piano.

Suo syömes mulle

Soitinnus: lauluääni, piano.

Myosin Va phosphorylated on ser(1650) is found in nuclear speckles and redistributes to nucleoli upon inhibition of transcription

Nuclear actin and nuclear myosins have been implicated in the regulation of geneexpression in vertebrate cells. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. In this study, myosin-Va, phosphorylated on a conserved serine in the tail domain (phospho-ser(1650) MVa), was localized to subnuclear compartments. A monoclonal antibody, 9E6, raised against a peptide corresponding to phosphoserine(1650) and flanking regions of the murine myosin Va sequence, was immunoreactive to myosin Va heavy chain in cellular and nuclear extracts of HeLa cells, PC12 cells and B16-F10 melanocytes. Immunofluorescence microscopy with this antibody revealed discrete irregular spots within the nucleoplasm that colocalized with SC35, a splicing factor that earmarks nuclear speckles. Phospho-ser(1650) MVa was not detected in other nuclear compartments, such as condensed chromatin, Cajal bodies, gems and perinucleolar caps. Although nucleoli also were not labeled by 9E6 under normal conditions, inhibition of transcription in HeLa cells by actinomycin D caused the redistribution of phospho-ser(1650) MVa to nucleoli, as well as separating a fraction of phosphoser(1650) MVa from SC35 into near-neighboring particles. These observations indicate a novel role for myosin Va in nuclear compartmentalization and offer a new lead towards the understanding of actomyosin-based gene regulation.

Uma amarra ao mar e outra à terra. Cristãos-novos no Algarve (1558-1650)

Tese apresentada para cumprimento dos requisitos necessários à obtenção do grau de Doutor em História Económica e Social Moderna

Mental Health Services in NI VFM Review Regional Summary (PDF 1650 KB)

June 2000 - to review whether the strategy for mental health services is based on clearly defined needs

Budjetti vuodelle 1937, 10 Pl XIV luku

Puhe

Budjetti vuodelle 1937, 10 Pl VI luku

Puhe

Budjetti vuodelle 1937, 10 Pl XIV luku

Puhe