Understanding the abnormal brain activity in epilepsy as a potential predictor of the onset of an epileptic seizure

The Brain Research Institute (BRI) uses various types of indirect measurements, including EEG and fMRI, to understand and assess brain activity and function. As well as the recovery of generic information about brain function, research also focuses on the utilisation of such data and understanding to study the initiation, dynamics, spread and suppression of epileptic seizures. To assist with the future focussing of this aspect of their research, the BRI asked the MISG 2010 participants to examine how the available EEG and fMRI data and current knowledge about epilepsy should be analysed and interpreted to yield an enhanced understanding about brain activity occurring before, at commencement of, during, and after a seizure. Though the deliberations of the study group were wide ranging in terms of the related matters considered and discussed, considerable progress was made with the following three aspects. (1) The science behind brain activity investigations depends crucially on the quality of the analysis and interpretation of, as well as the recovery of information from, EEG and fMRI measurements. A number of specific methodologies were discussed and formalised, including independent component analysis, principal component analysis, profile monitoring and change point analysis (hidden Markov modelling, time series analysis, discontinuity identification). (2) Even though EEG measurements accurately and very sensitively record the onset of an epileptic event or seizure, they are, from the perspective of understanding the internal initiation and localisation, of limited utility. They only record neuronal activity in the cortical (surface layer) neurons of the brain, which is a direct reflection of the type of electrical activity they have been designed to record. Because fMRI records, through the monitoring of blood flow activity, the location of localised brain activity within the brain, the possibility of combining fMRI measurements with EEG, as a joint inversion activity, was discussed and examined in detail. (3) A major goal for the BRI is to improve understanding about ``when'' (at what time) an epileptic seizure actually commenced before it is identified on an eeg recording, ``where'' the source of this initiation is located in the brain, and ``what'' is the initiator. Because of the general agreement in the literature that, in one way or another, epileptic events and seizures represent abnormal synchronisations of localised and/or global brain activity the modelling of synchronisations was examined in some detail. References C. M. Michel, G. Thut, S. Morand, A. Khateb, A. J. Pegna, R. Grave de Peralta, S. Gonzalez, M. Seeck and T. Landis, Electric source imaging of human brain functions, Brain Res. 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Overview No.144 - Mechanical behavior of amorphous alloys

The mechanical properties of amorphous alloys have proven both scientifically unique and of potential practical interest, although the underlying deformation physics of these materials remain less firmly established as compared with crystalline alloys. In this article, we review recent advances in understanding the mechanical behavior of metallic glasses, with particular emphasis on the deformation and fracture mechanisms. Atomistic as well as continuum modeling and experimental work on elasticity, plastic flow and localization, fracture and fatigue are all discussed, and theoretical developments are connected, where possible, with macroscopic experimental responses. The role of glass structure on mechanical properties, and conversely, the effect of deformation upon glass structure, are also described. The mechanical properties of metallic glass-derivative materials – including in situ and ex situ composites, foams and nanocrystal-reinforced glasses – are reviewed as well. Finally, we identify a number of important unresolved issues for the field.

Sapientia, 1982, Vol. XXXVII, nº 144 (número completo)

Contenido: La participación del ser II : la participación de la esencia / Octavio N. Derisi – Averroes, una fuente tomista de la noción metafísica de Dios / Alfonso García Marqués – La reducción de la metafísica clásica en Schelling (cont.) / Juan Cruz Cruz – Metafísica y teoría de sistemas en Ervin Laszlo / Mauricio Beuchot ; José Jaime Guerrero – Consideraciones sobre el idealismo jurídico / Juan A. Casaubón – Notas y comentarios -- Bibliografía

Estudio preliminar de ensilaje de Pennisetum purpureum cv. Taiwán A-144 mas pulpa de jícaro (Crescentia alata HBK)

Se está desarrollando el cultivo de jícaro (Crescentia alata) y el procesamiento de sus frutos provee un subproducto: la Pulpa. Se vio necesario verificar el efecto que esta ejerce sobre el cambio químico y fermentativo en el proceso de ensilaje al mezclarla con forraje Taiwán. En la hacienda “las Mercedes” ubicada en el kilómetro once y medio de la carretera norte, Managua, se estableció un ensayo que duró 101 días, el que consistió en analizar el efecto de mezclar Taiwán con pulpa de jícaro a diferentes proporciones, sobre los cambios químicos y fermentativos que éste ejerce durante el proceso de ensilaje. Las porciones utilizadas fueron A-100% Taiwán, B 95% Taiwán más 5%, C-90% mas 10% pulpa y D 85% mas 15% pulpa. Se utilizaron solo de tipo trinchera a escala experimental con capacidad de 41.6 kg., los que fueron muestreados a los 30, 40, y 50 días para sus respectivos análisis bromatológicos. Los resultados reportaron que el valor nutritivo de los ensilajes fue superior al encontrado en el material antes de ensilar: El alto contenido de proteína bruta encontrada en la proporción D, no favoreció un mejor comportamiento de los A:G:V:, ya que esta condujo a un cambio del patrón fermentativo en relación con las demás proporciones, predominantes en esta la fermentación acética: este cambio se debió al efecto temporizaste que las proteínas ejercen sobre el ensilaje dificultando la estabilidad del mismo. La proporción que mostró mejor comportamiento en los parámetros fermentativos fue la B, la que también registro un contenido de proteínas bruta por encima del 10%. Se requiere continuar estudios con el fin de encontrar un valor proporcional óptimo de Taiwán, mas pulpa de jícaro en el rango comprendido entre 5 y 10%.

Primeira avaliação orçamentária de 2010 : contingenciamento de março (Decreto 7.144/10)

Consultoria de Orçamento e Fiscalização Financeira - Núcleo de Assuntos Econômico-Fiscais.

Diário da Constituinte [gravação de vídeo] : [programa n. 144 A]

Depois de dois dias de debates, a Convenção do PMDB resolveu que a Assembleia Nacional Constituinte (ANC) é soberana para definir o sistema de governo e a duração do mandato do Presidente José Sarney. Luiz Henrique da Silveira (PMDB-SC) considera que foi um resultado de equilíbrio, que vai permitir ao PMDB fazer uma análise sensata e adotar o que for melhor para o Brasil e para a democracia. Mário Covas (PMDB-SP) afirma que partido que discute não racha. Um grupo do PMDB decidiu analisar os resultados da Convenção, vão defender 4 anos de mandato para o Presidente Sarney e acham que vai ser impossível manter o partido unido na Assembleia Nacional Constituinte. Domingos Leonelli (PMDB-BA) diz que o povo precisa de um partido e que, se o PMDB se negar a ser esse partido, um verdadeiro MDB terá de ser construído. O Governador de Pernambuco Miguel Arraes considera que o PMDB sai da Convenção unido, com as bandeiras que sempre defendeu. O Governador de São Paulo Orestes Quércia afirma que a Convenção definiu um sentido de unidade e trabalhou em benefício do partido e do país. O Governador do Rio de Janeiro Moreira Franco diz que a unidade do PMDB é hoje a condição fundamental para a transição democrática e para sustentar a possibilidade de termos uma Constituição que garanta a liberdade e a justiça social. O sistema de governo e a duração do mandato do Presidente Sarney voltam a ser discutidos por toda a ANC. O Governador da Bahia Waldir Pires, Plínio Arruda Sampaio (PT-SP), o Ministro das Comunicações Antonio Carlos Magalhães e Eduardo Bomfim (PC do B-AL) comentam os temas e a posição do PMDB. Ulysses Guimarães (PMDB-SP) entende que um partido moderno não gravita apenas em torno de ambições pessoais, mas principalmente em torno de compromissos com a coletividade e com a nação, tendo sido isso que o PMDB fez com grande sucesso.

Diário da Constituinte [gravação de vídeo] : [programa n. 144]

No Plenário da Comissão de Sistematização, constituintes defendem suas emendas para que sejam aprovadas. O Deputado Osvaldo Bender (PDS-RS) quer propiciar o acesso de todos os estudantes às universidades. O Senador Leopoldo Peres (PMDB-AM) defende as pequenas e médias empresas. O Deputado Sérgio Spada (PMDB-PR) propõe uma auditoria para verificar a dívida externa. No 8º Congresso Extraordinário do Partido Comunista Brasileiro (PCB) ficou definido que os comunistas irão defender, na Assembleia Nacional Constituinte, o parlamentarismo e quatro anos de mandato para o Presidente José Sarney, com eleições diretas em 1988. Salomão Malina, dirigente do PCB, espera que a Constituição seja um instrumento que facilite a luta do povo brasileiro por melhores condições de vida. Wanderlino Carvalho, Presidente da Coordenação Nacional dos Geólogos, pede aos brasileiros a participação nas emendas populares em favor da população indígena. Na Convenção Nacional do PMDB ficou decidido transferir para a Assembleia Nacional Constituinte (ANC) a atribuição de estipular a duração do mandato do Presidente Sarney e o sistema de governo.

利用水生植物清除水体中放射性物质的研究 (Ⅲ)水生植物对Sr~(90)、Y~(91)、Cs~(137)、Ce~(144)的积累、释放及Ca对Sr~(90)吸收的影响

5种水生植物对所用4种放射性同位素都有一定的清除能力,其清除能力的大小不仅取决于生物的种类,而且还取决于生物本身代谢率的高低。试验结果:去污率高的可达80%,积累系数最高可达1,500;水体中含Ca量的多少对生物吸收积累放射性物质的多少有一定的影响;生物在积累放射性物质之后,转移到无放射性物质的水体中将释放出原积累的一部分放射性物质。

Possible magnetic and antimagnetic rotations in Dy-144

High spin states of Dy-144 have been studied through in-beam gamma-ray spectroscopy by using the reaction Mo-92(Fe-56,2p2n). It has been found that the continuation of the ground-state band forks into three Delta I=2 bands above the 8(+) state. This forking has been attributed to the alignments of pi h(11/2)(2) or nu h(11/2)(-2) configurations with the help of the systematics in neighboring nuclei. Additionally a negative-parity sideband of Delta I=2 cascades has been observed to start from the 5((-)) state and continue to a dipole band above the (13(-)) state through another negative-parity sideband of Delta I=2 cascades in between. These structures have been discussed from the viewpoint of a competition between "Magnetic Rotation" and "Anti-magnetic Rotation" based on a classical particles-plus-rotor model.

Reseña: Elvira Narvaja de Arnoux y Susana Nothstein (eds.) (2014), Temas de glotopolítica: integración regional sudamericana y panhispanismo, Buenos Aires, Biblos, coll. “Investigaciones y ensayos”, 376 p. [ISBN: 978-9-876-91257-0]

Résumé non disponible

L'armée d'Orient : drame militaire en cinq ["sic" pour trois] actes et 20 tableaux. [suivi de] Ou passerai-je mes soirées : comédie-vaudeville en un acte. Livr. 144 / par MM. Albert et de Lustières ; par MM. Charles Potier et Gaston de Montheau

Collection : Théâtre contemporain illustré ; 143e et 144e livraisons