595 resultados para 1321


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Acheté en mars 1819 à la vente de feu M. Lair; cf. Catalogue des livres rares et précieux du cabinet de feu M. Lair, Paris, 1819, 51 n° 486

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Rapport sur la vie du P. Ricci, daté de 1586 (date erronée, il faut sans doute lire 1616) ; présenté par les PP. de Pantoja (1571-1618) et Sabbathinus de Ursis (1575-1617).

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Contient : HAYMAR, ou AYMAR le moine, De viribus Agarenorum, traduction française attribuée à Bernard le Trésorier. Début : « Pape saint Innocent voult savoir les us et les coustumes du pays... aus Sarrazins... »

Relevância:

20.00% 20.00%

Publicador:

Resumo:

zum ersten Male hrsg. und ins Deutsche übertr. von Gerson Lange

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The adult skeletal muscle Na+ channel mu1 possesses a highly conserved segment between subunit domains III and IV containing a consensus protein kinase C (PKC) phosphorylation site that, in the neuronal isoform, acts as a master control for "convergent" regulation by PKC and cAMP-dependent protein kinase. It lacks an approximately 200-aa segment between domains I and II though to modulate channel gating. We here demonstrate that mu1 is regulated by PKC (but not cAMP-dependent protein kinase) in a manner distinct from that observed for the neuronal isoforms, suggesting that under the same conditions muscle excitation could be uncoupled from motor neuron input. Maximal phosphorylation by PKC, in the presence of phosphatase inhibitors, reduced peak Na+ currents by approximately 90% by decreasing the maximal conductance, caused a -15 mV shift in the midpoint of steady-state inactivation, and caused a slight speeding of inactivation. Surprisingly, these effects were not affected by mutation of the conserved serine (serine-1321) in the interdomain III-IV loop. the pattern of current suppression and gating modification by PKC resembles the response of muscle Na+ channels to inhibitory factors present in the serum and cerebrospinal fluid of patients with Guillain-Barré syndrome, multiple sclerosis, and idiopathic demyelinating polyradiculoneuritis.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

In ihrer Arbeit untersucht Miriam Montag-Erlwein den gesamten klösterlichen Quellenbestand der Abtei Heilsbronn von 1132 bis 1321. Dieser gibt Aufschluss über die Verbindungen innerhalb des Ordens, zur Universität Paris, über die Machtverhältnisse in Franken und über die identitätsstiftende Rolle des Klosters für den Adel und die Oberschicht.