Dual-pump Raman amplification with increased flatness using modulation instability

The application of modulation instability-initiated nonlinear broadening of two CW pumps at different wavelengths, in order to achieve superior gain ripple performance in broadband Raman amplifiers, is demonstrated for the first time experimentally. A particular example using Truewave and LEAF fibers is offered, in which the 0.1 dB gain ripple band is extended from 5 nm to 19 nm. Experimental results are in a good agreement with numerical modeling. Guidelines for optimal broadening are discussed. © 2005 Optical Society of America.

Tunable and multiple-wavelengths/temporal output from gain-switched diode laser and a four Bragg-grating fiber

The spectral narrowing and selective tuning of picosecond pulse outputs from gain-switched diode laser and a four Bragg-grating fiber, were investigated. The fiber used under investigation was designed to provide spectral narrowing and multiple wavelength/temporal output. The maximum transmission out of each of the four output fibers was ∼7.5 mW, for a current of 180 mA. The results show that an output of any combination of multiple wavelengths is only produced at modulation frequencies which satisfy resonant conditions for all cavity arms simultaneously.

Design of a fiber scheme for nonlinear Raman pump broadening through modulation instability

In this work we explore numerically an experimentally the dependence of the broadened spectra on the choice of fibers and we analyze a series of basic rules to be taken into account when using nonlinear broadening to reduce the gain ripple of broadband Raman amplifiers

Dual-pump Raman amplification with enhanced flatness using modulation instability

In this work, we utilize modulation instability to the broadening of the two CW-pumps of a wideband Raman amplifier. Applying nonlinear fiber process, we demonstrate a feasibility of a certain control over the broadening process, leading to clear improvements in the flatness of the amplifier gain over its operational bandwidth.

Nonlinear multicore waveguiding structures with balanced gain and loss

We study existence, stability, and dynamics of linear and nonlinear stationary modes propagating in radially symmetric multicore waveguides with balanced gain and loss. We demonstrate that, in general, the system can be reduced to an effective PT-symmetric dimer with asymmetric coupling. In the linear case, we find that there exist two modes with real propagation constants before an onset of the PT-symmetry breaking while other modes have always the propagation constants with nonzero imaginary parts. This leads to a stable (unstable) propagation of the modes when gain is localized in the core (ring) of the waveguiding structure. In the case of nonlinear response, we show that an interplay between nonlinearity, gain, and loss induces a high degree of instability, with only small windows in the parameter space where quasistable propagation is observed. We propose a novel stabilization mechanism based on a periodic modulation of both gain and loss along the propagation direction that allows bounded light propagation in the multicore waveguiding structures.

Linear binocular combination of responses to contrast modulation:contrast-weighted summation in first- and second-order vision

Binocular combination for first-order (luminancedefined) stimuli has been widely studied, but we know rather little about this binocular process for spatial modulations of contrast (second-order stimuli). We used phase-matching and amplitude-matching tasks to assess binocular combination of second-order phase and modulation depth simultaneously. With fixed modulation in one eye, we found that binocularly perceived phase was shifted, and perceived amplitude increased almost linearly as modulation depth in the other eye increased. At larger disparities, the phase shift was larger and the amplitude change was smaller. The degree of interocular correlation of the carriers had no influence. These results can be explained by an initial extraction of the contrast envelopes before binocular combination (consistent with the lack of dependence on carrier correlation) followed by a weighted linear summation of second-order modulations in which the weights (gains) for each eye are driven by the first-order carrier contrasts as previously found for first-order binocular combination. Perceived modulation depth fell markedly with increasing phase disparity unlike previous findings that perceived first-order contrast was almost independent of phase disparity. We present a simple revision to a widely used interocular gain-control theory that unifies first- and second-order binocular summation with a single principle-contrast-weighted summation-and we further elaborate the model for first-order combination. Conclusion: Second-order combination is controlled by first-order contrast.

The impact of pump phase-modulation and filtering on WDM signals in a fibre optical parametric amplifier

WDM signal degradation from pump phase-modulation in a one-pump 20dB net-gain fibre optical parametric amplifier is experimentally and numerically characterised for the first time using 10x59Gb/s QPSK signals.

Modulation of glucagon receptor pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

The glucagon and glucagon-like peptide-1 (GLP-1) receptors play important, opposing roles in regulating blood glucose levels. Consequently, these receptors have been identified as targets for novel diabetes treatments. However, drugs acting at the GLP-1 receptor, whilst having clinical efficacy, have been associated with severe adverse side-effects and targeting of the glucagon receptor has yet to be successful. Here we use a combination of yeast reporter assays and mammalian systems, to provide a more complete understanding of glucagon receptor signaling considering the effect of multiple ligands, association with the receptor-interacting protein, receptor activity modifying protein-2 (RAMP2) and individual G protein α-subunits. We demonstrate that RAMP2 alters both ligand selectivity and G protein preference of the glucagon receptor. Importantly, we also uncover novel cross-reactivity of therapeutically used GLP-1 receptor ligands at the glucagon receptor that is abolished by RAMP2 interaction. This study reveals the glucagon receptor as a previously unidentified target for GLP-1 receptor agonists and highlights a role for RAMP2 in regulating its pharmacology. Such previously unrecognized functions of RAMPs highlight the need to consider all receptor-interacting proteins in future drug development.

An organizational learning approach to expatriate cross-cultural adjustment, organizational commitment, and job satisfaction

The purpose of this study was to investigate the relationship between organizational learning and expatriation in overseas subsidiaries as well as in organizations as a whole. In doing so, two issues were addressed--(i) the use of expatriation as firms internationalize, and (ii) the significance of various factors to expatriate success as firms gain international experience. The sample of companies for this study was drawn from U.S. Fortune 500 multinational corporations (MNCs) in two sets of related industries--computers/electronics and petroleum/chemicals. Based on the learning that takes place within organizations as they increase their involvement overseas, a positive relationship was expected between international experience and expatriation when internationalization was low, and a negative relationship was expected when internationalization was high. Results indicate a significant positive relationship between country experience and the proportion of expatriates in that subsidiary when subsidiaries were relatively young, and a negative relationship, however not significant, for more mature subsidiaries. The relationship between overall firm degree of internationalization (DOI) and the proportion of expatriates in the firm as a whole was negative regardless of stage of internationalization, but this relationship was significant only for highly internationalized firms. It was further suspected that individual, environmental, and family-related characteristics would have a significant effect on the success of expatriates whose firms were low on internationalization, and that organizational characteristics would play a significant role in highly internationalized firms. Support for these hypotheses was received with respect to certain outcomes and some determinants of success. The preponderance of support was found for those addressing the effects of both environmental and family-related characteristics on the cross-cultural adjustment of expatriates in firms with little international experience. Considerable support was also found for those hypotheses addressing the impact of organizational characteristics on the job satisfaction levels of expatriates assigned to mature subsidiaries. The relevant literatures on organizational learning and expatriation are reviewed, and a model is developed underlying the logic of the hypotheses. Research methods are then described in full detail, results are reported, and implications for theory and for management are discussed. ^

Transcriptome Analysis Reveals New Insights into the Modulation of Endometrial Stromal Cell Receptive Phenotype by Embryo-Derived Signals Interleukin-1 and Human Chorionic Gonadotropin: Possible Involvement in Early Embryo Implantation

The presence of the conceptus in uterine cavity necessitates an elaborate network of interactions between the implanting embryo and a receptive endometrial tissue. We believe that embryo-derived signals play an important role in the remodeling and the extension of endometrial receptivity period. Our previous studies provided original evidence that human Chorionic Gonadotropin (hCG) modulates and potentiates endometrial epithelial as well as stromal cell responsiveness to interleukin 1 (IL1), one of the earliest embryonic signals, which may represent a novel pathway by which the embryo favors its own implantation and growth within the maternal endometrial host. The present study was designed to gain a broader understanding of hCG impact on the modulation of endometrial cell receptivity, and in particular, cell responsiveness to IL1 and the acquisition of growth-promoting phenotype capable of receiving, sustaining, and promoting early and crucial steps of embryonic development. Our results showed significant changes in the expression of genes involved in cell proliferation, immune modulation, tissue remodeling, apoptotic and angiogenic processes. This points to a relevant impact of these embryonic signals on the receptivity of the maternal endometrium, its adaptation to the implanting embryo and the creation of an environment that is favorable for the implantation and the growth of this latter within a new and likely hostile host tissue. Interestingly our data further identified a complex interaction between IL1 and hCG, which, despite a synergistic action on several significant endometrial target genes, may encompass a tight control of endogenous IL1 and extends to other IL1 family members.

Quasi-Orthogonal Space-Time Block Coding Using Polynomial Phase Modulation

Recently, polynomial phase modulation (PPM) was shown to be a power- and bandwidth-efficient modulation format. These two characteristics are in high demand nowadays specially in mobile applications, where devices with size, weight, and power (SWaP) constraints are common. In this paper, we propose implementing a full-diversity quasiorthogonal space-time block code (QOSTBC) using polynomial phase signals as modulation format. QOSTBCs along with PPM are used in order to improve the power efficiency of communication systems with four transmit antennas. We obtain the optimal PPM constellations that ensure full diversity and maximize the QOSTBC's minimum coding gain distance. Simulation results show that by using QOSTBCs along with a properly selected PPM constellation, full diversity in flat fading channels and thus low BER at high signal-to-noise ratios (SNR) can be ensured. More importantly, it is also shown that QOSTBCs using PPM achieve a better error performance than those using conventional modulation formats.

Investigation of PHY, MAC and APP layers for adaptive and cross-layer optimization in IEEE802.11 WLAN

Due to huge popularity of portable terminals based on Wireless LANs and increasing demand for multimedia services from these terminals, the earlier structures and protocols are insufficient to cover the requirements of emerging networks and communications. Most research in this field is tailored to find more efficient ways to optimize the quality of wireless LAN regarding the requirements of multimedia services. Our work is to investigate the effects of modulation modes at the physical layer, retry limits at the MAC layer and packet sizes at the application layer over the quality of media packet transmission. Interrelation among these parameters to extract a cross-layer idea will be discussed as well. We will show how these parameters from different layers jointly contribute to the performance of service delivery by the network. The results obtained could form a basis to suggest independent optimization in each layer (an adaptive approach) or optimization of a set of parameters from different layers (a cross-layer approach). Our simulation model is implemented in the NS-2 simulator. Throughput and delay (latency) of packet transmission are the quantities of our assessments. © 2010 IEEE.

La perception du temps et sa modulation par la température chez les guêpes parasitoïdes

Les modèles d'optimalité postulent que les animaux en quête de ressources utilisent le taux de gain de valeur adaptative pour optimiser plusieurs comportements tels que la répartition du temps lors de l’exploitation d‘un agrégat et l'investissement en progénitures. Bien que la durée de plusieurs comportements doit être régulée, peu d’évidences de la perception du temps sont actuellement disponibles pour les insectes et aucune pour les guêpes parasitoïdes, et ce malgré leur importance en tant que modèles écologiques. De plus, puisque les guêpes parasitoïdes sont poïkilothermes, cette capacité pourrait être affectée par la température. Nous avons supposé que les guêpes parasitoïdes auraient la capacité de percevoir le temps, à la fois de façon prospective (mesure du temps écoulé) et rétrospective (durée d'un événement passé), afin d'optimiser les décisions liées à l'exploitation d’agrégats d’hôtes et à la reproduction. Nous avons également émis l'hypothèse que la température aurait une incidence sur la perception du temps des guêpes parasitoïdes. Pour la mesure prospective du temps, nous avons utilisé la capacité d’apprentissage associatif de Microplitis croceipes (Hymenoptera: Braconidae). Les guêpes ont été entraînées à associer une odeur à la durée d'un intervalle entre des hôtes. Après leur entraînement, elles ont été testées dans un tunnel de vol avec un choix d’odeurs. Les guêpes ont choisi majoritairement l'odeur associée à l'intervalle de temps auquel elles étaient testées. Nous avons également investigué le rôle de la dépense énergétique sur la mesure du temps. Suite à une restriction de mouvement des guêpes pendant l'intervalle de temps entre les hôtes, elles choisissaient aléatoirement dans le tunnel de vol. L'absence de dépense énergétique les aurait rendues incapables de mesurer le temps. La dépense d'énergie est donc un substitut essentiel pour mesurer le temps. Pour la mesure rétrospective du temps, nous avons utilisé le processus d'évaluation de l'hôte de Trichogramma euproctidis (Hymenoptera: Trichogrammatidae). Certains trichogrammes utilisent la durée du transit initial sur l'œuf hôte afin d’en évaluer la taille et d’ajuster le nombre d’œufs à y pondre. Nous avons augmenté artificiellement la durée de transit initiale de T. euproctidis en suspendant l'œuf hôte pour le faire paraître plus gros qu'un œuf de taille similaire. Une augmentation de la durée de transit initiale a augmenté la taille de la ponte. Ceci démontre la capacité de T. euproctidis de mesurer la durée du transit initial, et donc d’une mesure du temps rétrospective. Pour déterminer si la température modifie la mesure du temps dans les espèces poïkilothermes, nous avons utilisé le comportement d’exploitation d’agrégats d’hôtes de T. euproctidis. Les modèles d’optimalités prédisent que les guêpes devraient rester plus longtemps et quitter à un faible taux de gain de valeur adaptative suite à un déplacement de longue durée plutôt que pour un déplacement de courte durée. Nous avons testé l'impact d'un déplacement de 24 h à différentes températures sur l'exploitation d’agrégats d’hôtes. Un déplacement à température chaude augmente le temps de résidence dans l’agrégat et diminue le taux de gain de valeur adaptative au moment de quitter ; ces comportements sont associés à un trajet de longue durée. L'inverse a été observé lors d’un déplacement à une température froide. Les températures chaude et froide ont modulé la mesure du temps en accélérant ou ralentissant l'horloge biologique, faisant paraître le déplacement respectivement plus long ou plus court qu’il ne l’était réellement. Ces résultats démontrent clairement que les guêpes parasitoïdes ont la capacité de mesurer le temps, autant rétrospectivement que prospectivement. Des preuves directes de leur capacité sont maintenant disponibles pour au moins deux espèces de guêpes parasitoïdes, une composante essentielle des modèles d'optimalité. Le rôle de la dépense énergétique dans la mesure du temps a aussi été démontré. Nos résultats fournissent également la preuve de l'impact de la température sur la perception du temps chez les insectes. L'utilisation de la dépense énergétique en tant que proxy pour mesurer le temps pourrait expliquer une partie de sa thermosensibilité, puisque les guêpes parasitoïdes sont poïkilothermes. Cette mesure du temps sensible à la température pourrait affecter des stratégies de lutte biologique. Sur le terrain, au début de la journée, la température de l'air sera similaire à la température de l'air autour des plantes infestées par des parasites, alors qu'elle sera plus chaude pendant la journée. En lutte biologique augmentative, les guêpes parasitoïdes libérées resteraient plus longtemps dans les agrégats d’hôtes que celles relâchées en début de journée.

Wavelength converters based on four-wave mixing in semiconductor optical amplifiers for advanced modulation formats

Les convertisseurs de longueur d’onde sont essentiels pour la réalisation de réseaux de communications optiques à routage en longueur d’onde. Dans la littérature, les convertisseurs de longueur d’onde basés sur le mélange à quatre ondes dans les amplificateurs optiques à semi-conducteur constituent une solution extrêmement intéressante, et ce, en raison de leurs nombreuses caractéristiques nécessaires à l’implémentation de tels réseaux de communications. Avec l’émergence des systèmes commerciaux de détection cohérente, ainsi qu’avec les récentes avancées dans le domaine du traitement de signal numérique, il est impératif d’évaluer la performance des convertisseurs de longueur d’onde, et ce, dans le contexte des formats de modulation avancés. Les objectifs de cette thèse sont : 1) d’étudier la faisabilité des convertisseurs de longueur d’onde basés sur le mélange à quatre ondes dans les amplificateurs optiques à semi-conducteur pour les formats de modulation avancés et 2) de proposer une technique basée sur le traitement de signal numérique afin d’améliorer leur performance. En premier lieu, une étude expérimentale de la conversion de longueur d’onde de formats de modulation d’amplitude en quadrature (quadrature amplitude modulation - QAM) est réalisée. En particulier, la conversion de longueur d’onde de signaux 16-QAM à 16 Gbaud et 64-QAM à 5 Gbaud dans un amplificateur optique à semi-conducteur commercial est réalisée sur toute la bande C. Les résultats démontrent qu’en raison des distorsions non-linéaires induites sur le signal converti, le point d’opération optimal du convertisseur de longueur d’onde est différent de celui obtenu lors de la conversion de longueur d’onde de formats de modulation en intensité. En effet, dans le contexte des formats de modulation avancés, c’est le compromis entre la puissance du signal converti et les non-linéarités induites qui détermine le point d’opération optimal du convertisseur de longueur d’onde. Les récepteurs cohérents permettent l’utilisation de techniques de traitement de signal numérique afin de compenser la détérioration du signal transmis suite à sa détection. Afin de mettre à profit les nouvelles possibilités offertes par le traitement de signal numérique, une technique numérique de post-compensation des distorsions induites sur le signal converti, basée sur une analyse petit-signal des équations gouvernant la dynamique du gain à l’intérieur des amplificateurs optiques à semi-conducteur, est développée. L’efficacité de cette technique est démontrée à l’aide de simulations numériques et de mesures expérimentales de conversion de longueur d’onde de signaux 16-QAM à 10 Gbaud et 64-QAM à 5 Gbaud. Cette méthode permet d’améliorer de façon significative les performances du convertisseur de longueur d’onde, et ce, principalement pour les formats de modulation avancés d’ordre supérieur tel que 64-QAM. Finalement, une étude expérimentale exhaustive de la technique de post-compensation des distorsions induites sur le signal converti est effectuée pour des signaux 64-QAM. Les résultats démontrent que, même en présence d’un signal à bruité à l’entrée du convertisseur de longueur d’onde, la technique proposée améliore toujours la qualité du signal reçu. De plus, une étude du point d’opération optimal du convertisseur de longueur d’onde est effectuée et démontre que celui-ci varie en fonction des pertes optiques suivant la conversion de longueur d’onde. Dans un réseau de communication optique à routage en longueur d’onde, le signal est susceptible de passer par plusieurs étages de conversion de longueur d’onde. Pour cette raison, l’efficacité de la technique de post-compensation est démontrée, et ce pour la première fois dans la littérature, pour deux étages successifs de conversion de longueur d’onde de signaux 64-QAM à 5 Gbaud. Les résultats de cette thèse montrent que les convertisseurs de longueur d’ondes basés sur le mélange à quatre ondes dans les amplificateurs optiques à semi-conducteur, utilisés en conjonction avec des techniques de traitement de signal numérique, constituent une technologie extrêmement prometteuse pour les réseaux de communications optiques modernes à routage en longueur d’onde.

IT Adoption and Usage in Non-Profit Organizations: a Cross-generational Case Study

A gulf has tended to develop between the adoption and usage of information technology by different generations, at the heart of which is different ways of experiencing and relating to the world around us. This research idea is currently being developed following data collection and feedback is sought on ways forward to enable impact. The research focuses on information technology in the form of multimedia. Multimedia meaning ‘media’ and ‘content’ that uses a combination of different content forms; or electronically integrated communication engaging all or most of the senses (e.g. graphic art, sound, animation and full-motion video presented by way of computer or other electronic means) mainly through presentational technologies. Although multimedia is not new, some organization’s particularly those in the non-profit sector do not always have the technical or financial resources to support such systems and consequently may struggle to adopt and support its usage amongst different generations. However non-profit organizations are being forced to pay more attention to the way they communicate with markets and the public due to the professionalism of communication everywhere in society. The case study used for this study is a church circuit comprising of 15 churches in the Midlands region of the United Kingdom which was selected due to the diverse age groups catered for within this type of non-profit organization. Participants in the study also had a range of skills, experiences and backgrounds which adds to the diversity of the population studied. Data gathered focused on the attitudes and opinions of the adoption and use of multimedia amongst different age groups. 395 questionnaires were distributed, comprising of 11 opinion questions and 4 demographic questions. 83% of the questionnaires were returned, representing 35% of the total circuit membership. Three people from each of the following age categories were also interviewed: 1920 – 1946 (Matures); 1947-1964 (Baby Boomers); 1965-1982 (Generation X); 1983-2004 (Net Generation). Results of the questionnaire and comments from the interviews were found not to tally with the widespread assumption that the younger generation is attracted by the use of multimedia in comparison to the older generation. The highest proportion of those who said that they gain more from a service enhanced by multimedia was from the Baby Boomers. Comments from interviews suggested that: ‘we need to embrace multimedia if we are to attract and retain the younger generation’; ‘multimedia often helps children to remain focused and clarifies the objective of the service’. However, because the younger generations’ world tends to be dominated by computer technology the questionnaire showed that they are more likely to have higher standards when it comes to the use of multimedia, such as identifying higher levels of equipment failing to work and annoying use of sounds compared to older age groups. In comparison problems experienced with multimedia for the Matures age group had the highest percentage of difficulty with the size of letters; the colour of letters and background and the sound not loud enough which is to be expected. Since every organization is unique any type of multimedia adopted and used should be specific to their needs, its stakeholders and the physical building in order to enhance that uniqueness and its needs. Giving thought to whether the type of multimedia is the best method for communicating the message to the particular audience alongside how technical and financial resources are best used can assist in accommodating different age groups that need to be catered for.