Clonal chromosomal alterations in fibroadenomas of the breast

A cytogenetic study on short-term cell cultures from 10 fibroadenomas of the breast is reported, Clonal chromosomal alterations were observed in all cases analyzed, involving preferentially chromosomes X, 12, 14, 20, and 22. Normal karyotypes were found in 34.9% of the cells. The present findings are discussed together with the reports on fibroadenomas and other benign lesions of the breast described in the literature. Although no specific chromosome abnormality to date can be attributed to a particular type of benign breast pathology, some recurrent alterations are starting to emerge and may characterize these benign breast lesions, differentiating them from their malignant counterparts. (C) 2001 Elsevier B.V. All rights reserved.

Cytogenetic analysis of five Hypostomus species (Siluriformes, Loricariidae)

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Interspecific chromosomal divergences in the genus Characidium (Teleostei: Characiformes: Crenuchidae)

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Cytogenetic Mapping of rRNAs and Histone H3 Genes in 14 Species of Dichotomius ( Coleoptera, Scarabaeidae, Scarabaeinae) Beetles

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Chromosomal features of nucleolar dominance in hybrids between the Neotropical fish Leporinus macrocephalus and Leporinus elongatus (Characiformes, Anostomidae)

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5S rDNA chromosomal mapping and COI sequence analysis reveal differentiation among distinct populations of a characid fish Serrapinnus notomelas

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Chromosomal Variability among Allopatric Populations of Erythrinidae Fish Hoplias malabaricus: Mapping of Three Classes of Repetitive DNAs

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Variability of 18S rDNA locus among Symphysodon fishes: chromosomal rearrangements

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Chromosomal diversification in populations of Characidium cf. gomesi (Teleostei, Crenuchidae)

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Evolutionary dynamics of heterochromatin in the genome of Dichotomius beetles based on chromosomal analysis

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Cytogenetic Mapping of the Retroelements Rex1, Rex3 and Rex6 among Cichlid Fish: New Insights on the Chromosomal Distribution of Transposable Elements

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Comparative Cytogenetic Analysis of the Genus Symphysodon (Discus Fishes, Cichlidae): Chromosomal Characteristics of Retrotransposons and Minor Ribosomal DNA

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Chromosome differentiation patterns during cichlid fish evolution

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Chromosomal painting and ZW sex chromosomes differentiation in Characidium (Characiformes, Crenuchidae)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)