Bioactive Metabolites and Biomarkers from Rhizophoraceae mangroves- A Chemotaxonomic Approach

Mangroves are specialised ecosystems developed along estuarine sea coasts and river mouths in tropical and subtropical regions of the world, mainly in the intertidal zone. Hence, the ecosystem and its biological components is under the influence of both marine and freshwater conditions and has developed a set of physiological adaptations to overcome problems of anoxia, salinity and frequent tidal inundations. This has led to the assemblage of a wide variety of plant and animal species of special adaptations suited to the ecosystem. The path of photosynthesis in mangroves is different from other glycophytes. There are modifications or alterations in other physiological processes such as carbohydrate metabolism or polyphenol synthesis. As they survive under extreme conditions of salinity, temperature, tides and anoxic soil conditions they may have chemical compounds, which protect them from these destructive elements. Mangroves are necessarily tolerant of high salt levels and have mechanisms to take up water despite strong osmotic potentials. Some also take up salts, but excrete them through specialised glands in the leaves. Others transfer salts into senescent leaves or store them in the bark or the wood. Still others simply become increasingly conservative in their water use as water salinity increases. A usual transportation or biosynthetic path as other plants cannot be expected in mangrove plants. In India, the states like West Bengal, Orissa, Andhra Pradesh, Tamil Nadu, Andaman and Nicobar Islands, Kerala, Goa, Maharashtra, and Gujarat occupy vast area of mangroves. Kerala has only 6 km2 total mangrove area with Rhizophora apiculata, Rhizophora mucronata, Bruguiera gymnorrhiza, Bruguiera cylindrica, Avicennia officinalis, Sonneratia caseolaris, Sonneratia apetala and Kandelia candal, as the important species present, most of which belong to the family Rhizophoraceae.Rhizophoraceae mangroves are ranked as “major elements of mangroves” as they give the real shape of this unique and interesting ecosystem and these mangrove species most productive and typical characteristic ecosystem of World renowned. It was found that the Rhizophoraceae mangrove extracts exhibit several bioactive properties. Various parts of these mangroves are used in ethnomedicinal practices. Even though extracts from these mangroves possess therapeutic activity against humans, animal and plant pathogens, the specific metabolites responsible for these bioactivities remains to be elucidated. Various parts of these mangroves are used in ethnomedicinal practices. There is a gap of information towards the chemistry of Rhizophoraceae mangroves from Kerala. Thorough phytochemical investigation can achieve the validity of ethnomedicines as well as apply the use of mangrove plants in the development of new drugs. Such studies can pave a firm base for their use in biomarker and chemotaxonomic studies as well as for the better management of the existing mangrove ecosystem. In this study, the various chemical parameters including minerals, biochemical components, bioactive and biomarker molecules were used to classify and assess the possible potentials of the mangrove plants of the true mangrove family Rhizophoraceae from Kochi.

Caste, livelihoods and livestock: an exploration of the uptake of livestock vaccination adoption among poor farmers in India

The study explores the uptake of livestock vaccination among poor farming communities in Tamil Nadu State, India by revisiting innovation diffusion theory. Overall, 601 farmers participated in the study. We found the adoption of particular vaccines was strongly influenced by socio-cultural grouping i.e. caste, rather than other factors such as income, age, education-level or gender. Adoption was also related to specific knowledge frames regarding disease causality, rather than any wider ethno-veterinary beliefs. Thus, the adoption of livestock vaccination is unlikely to improve without knowledge transfer activities, which acknowledge both social divisions and local epistemologies regarding animal health. Copyright © 2010 John Wiley & Sons, Ltd.

High prevalence of undernutrition and low dietary diversity in institutionalised elderly living in Sri Lanka

This research received no specific grant from any funding agency in the public, commercial and not-for-profit sectors. The authors wish to thank the participants, administrators and caregivers of the homes for elders for their enthusiastic cooperation and also the Nutrition Research Team of the Department of Applied Nutrition, Wayamba University of Sri Lanka, for their valuable assistance during the course of the study. The authors also wish to thank Mr. S. Rahanan for coordination and the assistance given in data collection especially in Tamil speaking participants. K.M.R designed and managed the study, interpreted the data and drafted the manuscript. M.P.P.M contributed to the data collection, data analysis and coordination of the study. M.W, K.G.J and J.A.L assisted in data interpretation and critical revision of the manuscript. The authors declare that there is no conflict of interest of any kind involved in this study or this publication. Ethical clearance for this study was obtained from the Ethical Review Committee of the Sri Lanka Medical Association (ERC/13-037).

The Devil’s Calculus: Mathematical Models of Civil War

In spite of the movement to turn political science into a real science, various mathematical methods that are now the staples of physics, biology, and even economics are thoroughly uncommon in political science, especially the study of civil war. This study seeks to apply such methods - specifically, ordinary differential equations (ODEs) - to model civil war based on what one might dub the capabilities school of thought, which roughly states that civil wars end only when one side’s ability to make war falls far enough to make peace truly attractive. I construct several different ODE-based models and then test them all to see which best predicts the instantaneous capabilities of both sides of the Sri Lankan civil war in the period from 1990 to 1994 given parameters and initial conditions. The model that the tests declare most accurate gives very accurate predictions of state military capabilities and reasonable short term predictions of cumulative deaths. Analysis of the model reveals the scale of the importance of rebel finances to the sustainability of insurgency, most notably that the number of troops required to put down the Tamil Tigers is reduced by nearly a full order of magnitude when Tiger foreign funding is stopped. The study thus demonstrates that accurate foresight may come of relatively simple dynamical models, and implies the great potential of advanced and currently unconventional non-statistical mathematical methods in political science.

The LTTE Proposals for an Interim Self-Governing Authority and Future of the Peace Process in Sri Lanka

The political brinkmanship of the Liberation Tigers of the Tamil Eelam has been illustrated vividly by the way in which it brought forward its proposals for an Interim Self-Governing Authority by exploiting the vulnerabilities of the United National Front Government. In the proposals the LTTE articulated its political intentions in concrete constitutional terms for the first time. The Proposals rationalize the armed struggle and a contractual agreement outside the Constitution. The plenary powers of the ISGA exceed the federal formula; effectively exclude the institutions of the state of Sri Lanka from the North-East; and clear the route for a separate state. This situation demands a redirection of the peace process which requires a clear political vision and a proper strategy with alternative proposals on the part of the government. In the face of present impasse of the peace process the challenges before the new Freedom Alliance government are formidable.

Pakavarkītaivacanam /

In Tamil.

Centamiḻ.

Description based on: Tokuti 64, pakuti 1 (Ceptampar 1968); title from cover.

Zend-Avesta, ouvrage de Zoroastre : contenant les Idées Théologiques, Physiques et Morales de ce Législateur, les Cérémonies du Culte Religieux qu'il a établi, et plusicurs traits importans relatifs à l'anncienne Histoire de Perses /

Mode of access: Internet.

Meykaṇṭacivatūṣaṇanikraham : Meykaṇṭacivastavam /

In Tamil.

Jāṉsaṉ Paṇṭitar iyaṟṟiya Rāsilas : eṉum kaṟpitakkataiyiṉ Tamiḻ moli̲peyarppu ;

Added title page: Translation of Rasselas : a tale by Dr. Johnson.

Needinool; or Moral instructions

Text in Tamil.

Naṉṉūṟ kāṇṭikaiyurai /

"Naṉku viḷakkiyum pala viṣayaṇkaḷ cērttum ariya utāraṇaṅkaṭkup poruḷeḻutiyum putupitt[atu]."

Pukaḻentippulavar iyaṟṟiya Pulantaraṉ tūtu.

In Tamil.

Cakalākampaṇṭitareṉṉum Tiruttuṟaiyūr Aruṇanticivācāriyār tiruvāymalarntaruḷiya Civañāṉacittiyār parapakṣam mūlamum : Tattuvappirakācaruraiyum /

In Tamil.

Mackenzie collection : a descriptive catalogue of the oriental manuscripts and other articles illustrative of the literature, history, statistics and antiquities of the South of India /

Collection now in Government Oriental Manuscripts Library, Madras.