Capacidade de Uso das Terras da Bacia do Ribeirão Água Fria – Bofete (SP)

A determinação da capacidade de uso das terras numa bacia é muito importante para o planejamento e uso do solo, pois o uso inadequado e sem planejamento dessas terras provocam a baixa produtividade das culturas. Este trabalho visou definir as classes homogêneas de capacidade de uso da terra da bacia do Ribeirão Água Fria - Bofete (SP) para atender ao planejamento de práticas de conservação do solo desta área. A bacia situa-se entre as coordenadas geográficas 22o 58' 30`` a 23o 04' 30`` de latitude S e 48o 09' 30`` a 48o 18' 30`` de longitude W Gr., apresentando uma área de 9.180,12 hectares. A carta de capacidade de uso da terra da bacia foi elaborada a partir da carta clinográfica obtida por Santos et al. (1999), mapa pedológico do Estado de São Paulo (Oliveira et al., 1999), da tabela de julgamento de classes de capacidade de uso do solo (França, 1963) e das recomendações constantes no manual para levantamento utilitário do meio físico e classificação das terras no sistema de capacidade de uso (Lepsch et al., 1983). A discriminação, o mapeamento e a quantificação das áreas das classes e subclasses de capacidade de uso pelo Sistema de Informação Geográfica - IDRISI apresentaram os seguintes valores: IIIe,s - 517,020 ha (5,63%); IIIs - 863,150 ha (9,40%); IVe - 846,730 ha (9,23%); VIe - 871,110 ha (9,49%) e VIIe - 6082,115 ha (66,25%). Os resultados permitiram concluir que a bacia essencialmente constituída por 2/3 pela subclasse VIIe, ou seja, são terras que podem ser utilizadas por pastagens com uso moderado ou florestas, pois apresentam problemas complexos de erosão por causa de sua declividade. O Sistema de Informação Geográfica IDRISI permitiu através de seus módulos discriminar, mapear e quantificar as áreas das classes e subclasses de capacidade de uso das terras da bacia com rapidez e confiabilidade.

Relações entre aquisição da percepção auditiva e aprendizagem da ortografia: consoantes soantes em questão

We compared the relationships between acquisition of auditory perception and the acquisition of sonorant consonants spelling in children of the first two grades of elementary school. The comparison was based on a procedure of identifying and writing the same set of words that presented phonological contrasts between them. As to the results, it was found: (1) gradation in the acquisition of subclasses within a larger class; (2) matches and mismatches between the two types of task; (3) increased adjustments in spelling and more mismatches in auditory perception with increasing enrollment. This set of results indicates, therefore, the complexity of the relationships between the acquisition of auditory perception and the acquisition of spelling, since, once contacted, their journey together at the same time promotes links and outcomes between them.

Utilização de sistema de informação geográfica na avaliação do uso da terra em Botucatu (SP)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mapeando o conhecimento em sistemas de classificação de bibliotecas

This study explores, in 3 steps, how the 3 main library classification systems, the Library of Congress Classification, the Dewey Decimal Classification, and the Universal Decimal Classification, cover human knowledge. First, we mapped the knowledge covered by the 3 systems. We used the “10 Pillars of Knowledge: Map of Human Knowledge”, which comprises 10 pillars, as an evaluative model. We mapped all the subject-based classes and subclasses that are part of the first 2 levels of the 3 hierarchical structures. Then, we zoomed into each of the 10 pillars and analyzed how the three systems cover the 10 knowledge domains. Finally, we focused on the 3 library systems. Based on the way each one of them covers the 10 knowledge domains, it is evident that they failed to adequately and systematically present contemporary human knowledge. They are unsystematic and biased, and, at the top 2 levels of the hierarchical structures, they are incomplete.

Insights on the structure of native CNF, an endogenous phospholipase A(2) inhibitor from Crotalus durissus terrificus, the South American rattlesnake

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Flavones from Erythrina falcata are modulators of fear memory

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Polimorfismos de genes associados à resposta imune humoral em indivíduos naturalmente infectados pelo Plasmodium vivax no Estado do Pará

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo da resposta imune de camundongos BALB/c com a proteína recombinante A2 de Leishmania chagasi

Pós-graduação em Microbiologia Agropecuária - FCAV

Análise de registros ortográficos de consoantes soantes no início da alfabetização

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Structure, organization, and expression of the alpha prolamin multigenic family bring new insights into the evolutionary relationships among grasses

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Capacidad de uso de la tierra en la cuenca de la Corriente del Lobo, Itatinga, São Paulo, Brasil

The objective of the research was to define the classes of use capacity of 2403.25 ha in the basin of the Corriente del Lobo - Itatinga (SP), (22°03'56" to 22°59'12" of latitude S and 48°38'47" to 48°41'25" of longitude W Gr.). The soil use capacity was obtained by using the SIG IDRISI 32 crossing the documents of steepness and soils and the document of judgment of classes of soil use capacity and of the utilitarian rising of the physical milieu. The classes and subclasses areas of use capacity presented the following values: IIIa - 68.60 ha (2.85%), IIIe,s - 1919.15 ha (79.86%); IIIe - 210.60 ha (8.76%); IVe - 3.38ha (0.14%); IVe,s - 157.42 ha (6.55%) and VIe,s - 44.10 ha (1.84%). The lands of the basin were distributed in three classes (III, IV and VI) and six subclasses but the biggest extension (79.9%) belonged to the subclass IIIe,s. The modules of the IDRISI allowed to discriminate, mapping and to quantify quickly the soil use capacity of the areas of classes and subclasses in the basin.

Análise de diversidade e expressão de retrotransposons ativos em espécies de Coffea

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise de diversidade e expressão de retrotransposons ativos em espécies de Coffea

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Identification of protein expression signatures in gastric carcinomas using clustering analysis

Background and Aim: The identification of gastric carcinomas (GC) has traditionally been based on histomorphology. Recently, DNA microarrays have successfully been used to identify tumors through clustering of the expression profiles. Random forest clustering is widely used for tissue microarrays and other immunohistochemical data, because it handles highly-skewed tumor marker expressions well, and weighs the contribution of each marker according to its relatedness with other tumor markers. In the present study, we e identified biologically- and clinically-meaningful groups of GC by hierarchical clustering analysis of immunohistochemical protein expression. Methods: We selected 28 proteins (p16, p27, p21, cyclin D1, cyclin A, cyclin B1, pRb, p53, c-met, c-erbB-2, vascular endothelial growth factor, transforming growth factor [TGF]-beta I, TGF-beta II, MutS homolog-2, bcl-2, bax, bak, bcl-x, adenomatous polyposis coli, clathrin, E-cadherin, beta-catenin, mucin (MUC) 1, MUC2, MUC5AC, MUC6, matrix metalloproteinase [ MMP]-2, and MMP-9) to be investigated by immunohistochemistry in 482 GC. The analyses of the data were done using a random forest-clustering method. Results: Proteins related to cell cycle, growth factor, cell motility, cell adhesion, apoptosis, and matrix remodeling were highly expressed in GC. We identified protein expressions associated with poor survival in diffuse-type GC. Conclusions: Based on the expression analysis of 28 proteins, we identified two groups of GC that could not be explained by any clinicopathological variables, and a subgroup of long-surviving diffuse-type GC patients with a distinct molecular profile. These results provide not only a new molecular basis for understanding the biological properties of GC, but also better prediction of survival than the classic pathological grouping.

Pattern of humoral immune response to Plasmodium falciparum blood stages in individuals presenting different clinical expressions of malaria

Abstract Background The development of protective immunity against malaria is slow and to be maintained, it requires exposure to multiple antigenic variants of malaria parasites and age-associated maturation of the immune system. Evidence that the protective immunity is associated with different classes and subclasses of antibodies reveals the importance of considering the quality of the response. In this study, we have evaluated the humoral immune response against Plasmodium falciparum blood stages of individuals naturally exposed to malaria who live in endemic areas of Brazil in order to assess the prevalence of different specific isotypes and their association with different malaria clinical expressions. Methods Different isotypes against P. falciparum blood stages, IgG, IgG1, IgG2, IgG3, IgG4, IgM, IgE and IgA, were determined by ELISA. The results were based on the analysis of different clinical expressions of malaria (complicated, uncomplicated and asymptomatic) and factors related to prior malaria exposure such as age and the number of previous clinical malaria attacks. The occurrence of the H131 polymorphism of the FcγIIA receptor was also investigated in part of the studied population. Results The highest levels of IgG, IgG1, IgG2 and IgG3 antibodies were observed in individuals with asymptomatic and uncomplicated malaria, while highest levels of IgG4, IgE and IgM antibodies were predominant among individuals with complicated malaria. Individuals reporting more than five previous clinical malaria attacks presented a predominance of IgG1, IgG2 and IgG3 antibodies, while IgM, IgA and IgE antibodies predominated among individuals reporting five or less previous clinical malaria attacks. Among individuals with uncomplicated and asymptomatic malaria, there was a predominance of high-avidity IgG, IgG1, IgG2 antibodies and low-avidity IgG3 antibodies. The H131 polymorphism was found in 44.4% of the individuals, and the highest IgG2 levels were observed among asymptomatic individuals with this allele, suggesting the protective role of IgG2 in this population. Conclusion Together, the results suggest a differential regulation in the anti-P. falciparum antibody pattern in different clinical expressions of malaria and showed that even in unstable transmission areas, protective immunity against malaria can be observed, when the appropriated antibodies are produced.