Adsorption of biomedical coating molecules, amino acids, and short peptides on magnetite (110)

Superparamagnetic iron oxide nanoparticles for biomedical applications are usually coated with organic molecules to form a steric barrier against agglomeration. The stability of these coatings is well established in the synthesis medium but is more difficult to assess in physiological environment. To obtain a first theoretical estimate of their stability in such an environment, we perform density functional theory calculations of the adsorption of water, polyvinyl alcohol (PVA) and polyethylene glycol (PEG) coating molecules, as well as the monomer and dimer of glycine as a prototype short peptide, on the (110) surface of magnetite (Fe3O4) in vacuo. Our results show that PVA binds significantly stronger to the surface than both PEG and glycine, while the difference between the latter two is quite small. Depending on the coverage, the wateradsorption strength is intermediate between PVA and glycine. Due to its strongly interacting OH side groups, PVA is likely to remain bound to the surface in the presence of short peptides. This stability will have to be further assessed by molecular dynamics in the solvated state for which the present work forms the basis.

Ms. Barth. 110 - Metamorphoseon Libri XV

Vorbesitzer: Bartholomaeusstift Frankfurt am Main

Frau Minna Klausner-Exin [Illustration] : geb. 1764 - gest. 1874 (110 Jahr alt)

Scan von Monochrom-Mikroform

Psalm 110

Hermann Baneth

Talmud Ketzuba 110 b : zur Geschichte der letzten Tage

H. York-Steiner

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 110 - Bericht über seine Erlebnisse mit dem Militär in Hamburg

u.a.: Pastor Schulz; Pastor Hubbe; Johanna Schopenhauer;

Ms. Praed. 110 - Sermones de tempore a paschate usque ad dominicam XXV

Vorbesitzer: Johannes Wirburg; Dominikanerkloster Frankfurt am Main

Ms.Ff.F.Stoltze 3. 110 - Brief von ... Hasenkamp an Friedrich Stoltze

"Der Prophet Jonas", Unmöglichkeit, dieses Gedicht im "Beobachter" abzudrucken, Persönliche Nachrichten, Pressprozesse

Ausst. 110/113 - Passionsdarstellungen: Pilatus wäscht sich die Hände; Dornenkrönung und Christi Verspottung; Christi Annagelung ans Kreuz; Die Abnahme vom Kreuz : Schrotblätter

Vorbesitzer: Karmeliterkloster Frankfurt am Main;

Ms. lat. oct. 110 - Stundenbuch nach dem Gebrauch von Utrecht-Windesheim

Vorbesitzer: Matthias ... (17. Jh.)

Na 1 Nachlass Max Horkheimer, 586 - Korrespondenzen mit Friedrich (Frederick) Pollock (p. VI 36, 110-334)

1 Brief von Frederick Pollock an Walter Munding, 16.08.1950; 1 Brief von Frederick Pollock an Joseph Christ, 24.05.1950; 1 Brief von Albert Flegenheimer an Frederick Pollock, 18.05.1950; 2 Briefe von Frederick Pollock an E. Wehrle, 03.04.1950; 1 Brief von Margot von Mendelssohn an Max Horkheimer, 18.01.1950; 1 Brief von Nothern Life Insurance Co. (Seattle) an Max Horkheimer, 16.01.1950;