963 resultados para Polarity


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The active migration of neurons from their sites of origin to their final destinations requires the unidirectional translocation of the nuclei and somatic cytoplasm within the growing leading processes. To explore the cellular machinery underlying this translocation, we determined the polarity of microtubules situated within the leading and trailing processes of migrating cerebellar granule cells in situ. Our analysis reveals that the newly assembled positive ends of the microtubules in the leading process uniformly face the growing tip, while their disintegrating negative ends face the nucleus. In the trailing process, by contrast, microtubule arrays are of mixed polarity. We suggest that the dynamics of slow polymerization in combination with fast disintegration of oriented microtubules create "push" and "pull" forces that contribute to the piston-like saltatory displacement of the nucleus and cytoplasm within the membrane cylinder of the leading process of the migrating neuron.

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In each facet of the Drosophila compound eye, a cluster of photoreceptor cells assumes an asymmetric trapezoidal pattern. These clusters have opposite orientations above and below an equator, showing global dorsoventral mirror symmetry. However, in the mutant spiny legs, the polarization of each cluster appears to be random, so that no equator is evident. The apparent lack of an equator suggests that spiny legs+ may be involved in the establishment of global dorsoventral identity that might be essential for proper polarization of the photoreceptor clusters. Alternatively, a global dorsoventral pattern could be present, but spiny legs+ may be required for local polarization of individual clusters. Using an enhancer trap strain in which white+ gene expression is restricted to the dorsal field, we show that white+ expression in spiny legs correctly respects dorsoventral position even in facets with inappropriate polarizations; the dorsoventral boundary is indeed present, whereas the mechanism for polarization is perturbed. It is suggested that the boundary is established before the action of spiny legs+ by an independent mechanism.

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The huge amount of data available on the Web needs to be organized in order to be accessible to users in real time. This paper presents a method for summarizing subjective texts based on the strength of the opinion expressed in them. We used a corpus of blog posts and their corresponding comments (blog threads) in English, structured around five topics and we divided them according to their polarity and subsequently summarized. Despite the difficulties of real Web data, the results obtained are encouraging; an average of 79% of the summaries is considered to be comprehensible. Our work allows the user to obtain a summary of the most relevant opinions contained in the blog. This allows them to save time and be able to look for information easily, allowing more effective searches on the Web.

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Actualmente existe una gran cantidad de empresas ofreciendo servicios para el análisis de contenido y minería de datos de las redes sociales con el objetivo de realizar análisis de opiniones y gestión de la reputación. Un alto porcentaje de pequeñas y medianas empresas (pymes) ofrecen soluciones específicas a un sector o dominio industrial. Sin embargo, la adquisición de la necesaria tecnología básica para ofrecer tales servicios es demasiado compleja y constituye un sobrecoste demasiado alto para sus limitados recursos. El objetivo del proyecto europeo OpeNER es la reutilización y desarrollo de componentes y recursos para el procesamiento lingüístico que proporcione la tecnología necesaria para su uso industrial y/o académico.

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Citation corpus composed by 85 articles taken randomly from ACL Anthology with a total of 2195 bibliography cites.

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Cores recovered at Sites 986 and 987 comprise glacial fan sedimentation associated with the Svalbard-Barents Sea and Greenland Ice Sheets, respectively. At Site 986, the top 150 m and the basal 250 m yielded interpretable magnetic stratigraphies. The record from the intervening 550 m is compromised by drilling-related core deformation, poor recovery, and numerous debris flows. The uppermost 150 m appears to record the Brunhes/Matuyama boundary and the Jaramillo Subchron. The base of the drilled section (at ~950 meters below seafloor [mbsf]) is interpreted to lie within the Matuyama Chron (age <2.58 Ma) with an apparent normal polarity interval in the ~730-750 mbsf interval. Dinoflagellate cyst biostratigraphy and Sr isotopic ratios are consistent with a Matuyama age for the base of the drilled section and with the normal polarity interval as the Olduvai Subchron. On the other hand, the last occurrence of Neogloboquadrina atlantica (sinistral) and the last common occurrence of the warm-dwelling Globigerina bulloides at 647-650 mbsf in Hole 986D indicate an age for this level of ~2.3 Ma, inconsistent with the designation of the Olduvai Subchron in the ~730-750 mbsf interval. If the age at 647-650 mbsf in Hole 986D is taken as 2.3 Ma and the base of the hole lies within the Matuyama Chron, then the sedimentation rate in the basal 300 m of the cored section averages 1 m/k.y. At Site 987, the magnetic stratigraphy is fairly unambiguous throughout the section and yields an age of 7.5 Ma (Chron 4n) for the base of the drilled section. The paucity of calcareous and siliceous microfossils precludes biostratigraphic corroboration of the magnetostratigraphic interpretation, although dinoflagellate cysts provide general support, particularly at the base of the section. The age model indicates relatively low sedimentation rates (~5 cm/k.y.) at the base of the section with rates at least four to five times greater during intervals of debris flows at ~5-4.6 and ~2.6 Ma.

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Magnetic polarity stratigraphies for Sites 980-984 are based on shipboard measurements from the pass-through magnetometer after alternating field (AF) demagnetization at a peak field of 25 mT and shore-based stepwise AF demagnetization of discrete samples. The characteristic magnetization component was determined after AF demagnetization removed the steep downward drill-string-related magnetic overprint. Peak AF fields in the 20-30 mT range were required to resolve the component, carried by magnetite, that was used to produce unambiguous Pliocene-Pleistocene magnetic stratigraphies at all five sites. At Sites 980 and 983, magnetic stratigraphies were resolved to the base of the recovered advanced hydraulic piston corer (APC) section, which lies in the Matuyama Chron (1r.2r) and Olduvai Subchron (2n), respectively. At Sites 981 and 982, magnetization intensities decrease sharply in the normal polarity zone corresponding to the Gauss Chron (2An), and magnetic stratigraphies below this level could not be resolved. At Site 984, the resolution of magnetic stratigraphy was curtailed at ~250 meters below seafloor (Olduvai Subchron) by core deformation at the base of the APC section and in the underlying extended core barrel section. As the magnetic stratigraphies at all four sites are unequivocal, polarity chron interpretations can be made without aid from the biostratigraphy. Mean sedimentation rates within polarity chrons have been calculated and Pliocene-Pleistocene biomagnetostratigraphic correlations tested.

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"Edition of 600 copies of which 500 are for sale."