Leprosy treatment dropout: A sistematic review

Background: Leprosy is a chronic infectious disease endemic in some undeveloped areas, and still represents a public health problem in Brazil. Therefore, the control of this endemic disease depends necessarily on the institution of correct treatment and containment of treatment dropout. This study aims to conduct a systematic review of published studies on treatment dropout of leprosy. Methods. We conducted a systematic review of articles on treatment dropout of leprosy, published between january 2005 and april 2013, on MEDLINE and SciELO databases. The search was performed using the MeSH terms: leprosy; patients dropouts and the keywords: leprosy, treatment and noncompliance, leprosy in association, beside the equivalents in Portuguese. Results: There were originally 196 references. After analyzing the titles and abstracts of articles, 20 articles were obtained and included in the final sample. Discussion. Leprosy is a notifiable disease known as its disfiguring capability and the high rate of non-compliance to treatment. The low adhesion is responsible for the remaining potential sources of infection, irreversible complications, incomplete cure and, additionally, may lead to resistance to multiple drugs. Many factors are responsible for the interruption or dropout treatment: socioeconomic factors, education level, knowledge about the disease, lack of efficiency of health services, demographics, side effects of drugs, alcoholism, among others. Conclusion: The recent scientific literature about the subject diverge regarding the factors that most affect the dropout problem in treating leprosy patients. However, better integration between professionals and users, and greater commitment of the patient, are common points among the authors of the studies. © 2013 Girão et al.; licensee BioMed Central Ltd.

O efeito de dois modelos de treinamento contínuo ou intervalado sobre metabolismo muscular e capacidade aeróbia de ratos obesos induzidos por dieta

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos do treinamento com pesos nos sintomas depressivos e variáveis metabólicas em pacientes com doença de Alzheimer

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Programa domiciliar de exercícios motores e cognitivos para pacientes no estágio avançado da doença de Alzheimer

Pós-graduação em Ciências da Motricidade - IBRC

Terapia ocupacional modulando a dor em pacientes oncológicos sob cuidados paliativos

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Efeito agudo de CPAP na funçao diastólica ventricular e na capacidade funcional de pacientes com insuficiência cardíaca

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Efeitos do treinamento físico associado à suplementação de L-arginina na resposta relaxante de artéria femoral de ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise de protocolos com intervenção motora domiciliar para pacientes com doença de Alzheimer: uma revisão sistemática

The regular practice of physical therapy is indicated as a non-pharmacological treatment of Alzheimer's disease by promoting cognitive, behavioral and functional benefits. However, little is known about the protocols with home-based motor intervention for this population. Thinking about it, this review aimed to investigate and analyze the protocols for home-based motor intervention for elderly with Alzheimer's disease described in scientific articles. A systematic search was performed in the following databases: Web of Science, PubMed, PsycINFO, and Scopus, using the following keywords and Boolean operators: home-based exercise OR home-based physical exercise OR home-based physical fitness OR home-based rehabilitation OR home-based physical therapy OR home-based physical activity OR home-based engine Intervention and AD OR Alzheimer's disease OR AlzheimerOR Alzheimer's dementia. We also conducted a manual search of reference lists of selected articles. Of the five articles that met the inclusion criteria adopted, three performed a protocol for home motor intervention, achieving good compliance with the program, improvement of general health and reduction of depressive symptoms. The other two studies were limited to describing the protocols. Although more studies are needed, with detailed protocols, this review allowed to show that protocols for home motor intervention can also produce positive effects for both patients and caregivers.

Exercise training decreases mitogen-activated protein kinase phosphatase-3 expression and suppresses hepatic gluconeogenesis in obese mice

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pathogen levels and clinical response to periodontal treatment in patients with Interleukin 8 haplotypes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização da resposta hipotensora pós-exercício

Hypertension is a disease that affects a large part of the world population, in which the treatment consists in changing habits of life, which include diet, weight loss and smoking cessation, among others, attending the physical activity outstanding recommendations, supported by its positive effects on the maintenance of blood pressure levels within the limits of normality. Objective: To characterize the post-exercise hypotensive response on individuals with hypertension. Method: Literature review from 1990 to 2011, searching the electronic databases MEDLINE, ScIELO, Lilacs and Cochrane. Articles were selected using keywords hypertension, physical exercise and high blood pressure. Results: One session of physical activity promotes the reduction of arterial hypertension, which is called post-exercise hypotension. However, this phenomenon will depend on some related factors such as the type, intensity and duration of exercise. Conclusion: The performance of activity and/or physical exercise is important in non-pharmacological treatment for lowering blood pressure, but is not yet defined the best type of exercise.

Análise cinemática da marcha livre e adaptativa de pacientes com doença de Parkinson e idosos sadios: efeito da dica auditiva

Disorders in gait are identified in Parkinson’s disease patients. As a result, the capacity of walking independently and the interaction with the environment can be impairment. So, the auditory cues have been utilized as a non-pharmacological treatment to improve the locomotor impairment of the PD patients. However, these effects were observed in the regular lands and it’s not known the effects of auditory cues in gait during avoidance obstacles that could be more threaten for these patients. Yet, few studies in the literature compare the Parkinson’s disease patients with the older adults during the locomotor tasks and obstacle avoidance in association with the effects of auditory cues. The aim of the study is to compare the effects of the auditory cues in the gait and during obstacle avoidance in PD patients and older adults. 30 subjects distributed in two groups (Group 1 - 15, Parkinson’s disease patients; Group 2 - 15, healthy older adults) are going to participate of this study. After the participation approval, the assessment of clinical condition will be done by a physician. So, to investigate the locomotor pattern, it will be done a kinematic analysis. The experimental task is to walk on 8 m pathway and 18 trials will be done (6 for the free gait and 12 for adaptive gait). For the adaptive gait, two different obstacle heights will be manipulated: high obstacle (HO) and low obstacle (LO). In order to verify possible differences between the groups and the experimental condition, multivariance tests will be used with a significance level of 0.05. MANOVA revealed effect of condition and task. Thus, with DA, we observed an increase in cadence and reduced single support and stride length. When the tasks were compared, it was observed that the LO task, subjects had lower velocity and stride length... 9Complete abstract click electronic access below)

Laserterapia em lesões de coluna na Medicina Veterinária

Lasertherapy is a method of non-pharmacological treatment and surgery that can be used in several injuries and in various tissues, from bone fractures to tendonitis, skin wounds and damaged nerves, permitting the recovery of these structures and their functions without causing any side effects. Laser therapy aims to restore patients that suffered various injuries, such as bone fracture, inflammation, edema, tendon rupture, spinal cord injury, among others, without invasive intervention, and the results obtained in several studies and case reports have proven the high potential of this therapy to become an official treatment of various pathological changes

Efeito do treinamento com pesos nos distúrbios do sono e na qualidade de vida de pacientes com demência de Alzheimer

The Alzheimer's dementia (AD) is the most prevalent form of dementia in the elderly. Among the harmful changes arising from the DA, there may be sleep disturbance and impaired quality of life. Physical activity is an important non-pharmacological feature that would provide positive effects for the treatment of disease. However, there are still few studies that clarify the effects of resistance training in this population. Thus, the present study has as objective analyzes the effects of the resistance training in sleep disturbance and quality of life of patients with AD. Participated in this study 22 patients with clinical diagnosis of AD divided into two groups: Training Group (TG) and Social Interaction Group (SIG). The subjects of TG underwent a resistance training protocol, appropriate to the individual conditions, during three days no consecutive in the week, with duration of 60 minutes each session, for 16 weeks. The SIG won't participate in any systematized physical activity, but they realized other activities, such as reading, poetry, hiking and painting, among others. This protocol also was realized three times in week for 16 weeks, with duration of 60 minutes each session. Both groups were assessed at the beginning of the program and after 16 weeks. For the assessment of sleep disturbance was used the Mini Sleep Questionnaire and to assess of quality of life was used the Scale for Assessment of Quality of Life in Alzheimer's disease (QL), versions: patient, caregiver, family and the final score. Due to the scalar nature of the data and small sample, all variables were analyzed by nonparametric statistics. The U-Mann Whitney test, Wilcoxon test and Spearman correlation test was used, except for the Modified Baecke... (Complete abstract click electronic access below)

Exercício físico e funções cognitivas em pacientes com doença de Alzheimer: associação com BDNF e APOE

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)