1000 resultados para Järvinen-Tassopoulos, Johanna


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Historisches taschenbuch, N.F., 1845, vi. 445-490.

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Rezension von: Michael Schratz / Johanna F. Schwarz / Tanja Westfall-Greiter: Lernen als bildende Erfahrung, Vignetten in der Praxisforschung, Mit einem Vorwort von Käte Meyer-Drawe und Beiträgen von Horst Rumpf, Carol Ann Tomlinson, Mike Rose u.a., Innsbruck: Studienverlag 2012 (161 S.; ISBN 978-3706551182)

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Rezension von: Helga Kelle / Johanna Mierendorff (Hrsg.): Normierung und Normalisierung der Kindheit. Weinheim und Basel: Beltz Juventa 2013 (198 S.; ISBN 978-3-7799-1555-3)

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Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of oral cancer. Hence, in this study we have investigated the proteomic and peptidomic profiles by combining an orthotopic murine model of oral squamous cell carcinoma (OSCC), mass spectrometry-based proteomics and biological network analysis. Our results indicated the up-regulation of proteins involved in actin cytoskeleton organization and cell-cell junction assembly events and their expression was validated in human OSCC tissues. In addition, the functional relevance of talin-1 in OSCC adhesion, migration and invasion was demonstrated. Taken together, this study identified specific processes deregulated in oral cancer and provided novel refined OSCC-targeting molecules.