Richardi Sancti Victoris ... O[mn]ia opera in vnum volumen congesta solerti cura ac diligentia emendata atq[ue] nunc primum parrisiis impressa.

Lugar y fecha de imp. tomados del colofón

Practica iudiciaria / Ia[cobi] de bel[lo] visu sole[m]nis [et] iudicibus o[mn]ibus, aduocatisq[ue] [et] practicis cu[n]ctis nedu[m] vtilis[s]immo p[er]necessaria Practica Iudiciaria in materijs criminalib[us] ... Iacobi de bellouisu ; cu[m] additionib[us]

Ubaldi, Baldo degli, 1327-1400. Practica Baldi 1525 : perutilis ac vere aurea practica iuris vtriusq[ue] monarche ac luminis. Impressum Lugduni : in calcographia dilige[n]tissimi i[m]pressoris Iohannis Crespin, 1525, 17 Augusti. [12], XCVI h. Sign.: A8,

Practica iudiciaria / Ia[cobi] de bel[lo] visu sole[m]nis [et] iudicibus o[mn]ibus, aduocatisq[ue] [et] practicis cu[n]ctis nedu[m] vtilis[s]immo p[er]necessaria Practica Iudiciaria in materijs criminalib[us] ... Iacobi de bellouisu ; cu[m] additionib[us] celeberrimi d[omi]ni Honorati Pugeti ... ; Ad vngue[m] quoq[ue] p[er] Celsum Hugone[m] dissutu[m] …

Hojas imp. por ambas caras

Gure borondatea Jaungoikoarenarekin elkartzea / Alfonso Maria Ligorio'tar Santuak Italia'ko itzkuntzan jarri zuanetik ; erredentorista beneragarri Aita Tomas Ramos'tarrak gastelaniaz ipiñia ; eta apaiz euskaldun batek euskerara itzulia.

Dialecto : texto en euskera central -- guipuizcoano

D. Jacobi Parez [sic] de Vale[n]tia ... ordinis diui Augustini ... expositiones in. CL. psal. Dauidicos ... Cantica ferialia in biblijs contenta. Cantica eua[n]gelica B[e]n[e]dictus Magnificat nu[n]c dimit. Gl[or]ia in excel. Ca[n]ticu[m] Amb. et Aug. Te Deum. Cantica canticor[um] Premissis Questio[n]ib[us] et earu[m] subtilissimis resolutionibus co[n]tra Judeos nostre fidei adversa [Texto impreso] : Cum tabula in totu[m] opus collecta

Marca tip. en port. y colofón en h. [27]

Characterization of a high-voltage-activated IA current with a role in spike timing and locomotor pattern generation

Transient A-type K+ channels (IA) in neurons have been implicated in the delay of the spike onset and the decrease in the firing frequency. Here we have characterized biophysically and pharmacologically an IA current in lamprey locomotor network neurons that is activated by suprathreshold depolarization and is specifically blocked by catechol at 100 μM. The biophysical properties of this current are similar to the mammalian Kv3.4 channel. The role of the IA current both in single neuron firing and in locomotor pattern generation was analyzed. The IA current facilitates Na+ channel recovery from inactivation and thus sustains repetitive firing. The role of the IA current in motor pattern generation was examined by applying catechol during fictive locomotion induced by N-methyl-d-aspartate. Blockade of this current increased the locomotor burst frequency and decreased the firing of motoneurons. Although an alternating motor pattern could still be generated, the cycle duration was less regular, with ventral roots bursts failing on some cycles. Our results thus provide insights into the contribution of a high-voltage-activated IA current to the regulation of firing properties and motor coordination in the lamprey spinal cord.

In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections.

Urinary tract infections, caused mainly by Escherichia coli, are among the most common infectious diseases. Most isolates of the uropathogenic E.coli can express type 1 and P fimbriae containing adhesins that recognize cell receptors. While P fimbriae recognize kidney glycolipid receptors and are involved in peyelonephritis, the urothelial for type 1 fimbriae were not identified. We show that type 1-fimbriated E. coli recognize uroplakins Ia and Ib, two major glycoproteins of urothelial apical plaques. Anchorage of E. coli to urothelial surface via type 1 fimbriae-uroplakin I interactions may play a role in its bladder colonization and eventual ascent through the ureters, against urine flow, to invade the kidneys.

IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.

IA-2 is a 105,847 Da transmembrane protein that belongs to the protein tyrosine phosphatase family. Immunoperoxidase staining with antibody raised against IA-2 showed that this protein is expressed in human pancreatic islet cells. In this study, we expressed the full-length cDNA clone of IA-2 in a rabbit reticulocyte transcription/translation system and used the recombinant radiolabeled IA-2 protein to detect autoantibodies by immunoprecipitation. Coded sera (100) were tested: 50 from patients with newly diagnosed insulin-dependent diabetes mellitus (IDDM) and 50 from age-matched normal controls. Sixty-six percent of the sera from patients, but none of the sera from controls, reacted with IA-2. The same diabetic sera tested for autoantibodies to islet cells (ICA) by indirect immunofluorescence and glutamic acid decarboxylase (GAD65Ab) by depletion ELISA showed 68% and 52% positivity, respectively. Up to 86% of the IDDM patients had autoantibodies to IA-2 and/or GAD65. Moreover, greater than 90% (14 of 15) of the ICA-positive but GAD65Ab-negative sera had autoantibodies to IA-2. Absorption experiments showed that the immunofluorescence reactivity of ICA-positive sera was greatly reduced by prior incubation with recombinant IA-2 or GAD65 when the respective antibody was present. A little over one-half (9 of 16) of the IDDM sera that were negative for ICA were found to be positive for autoantibodies to IA-2 and/or GAD65, arguing that the immunofluorescence test for ICA is less sensitive than the recombinant tests for autoantibodies to IA-2 and GAD65. It is concluded that IA-2 is a major islet cell autoantigen in IDDM, and, together with GAD65, is responsible for much of the reactivity of ICA with pancreatic islets. Tests for the detection of autoantibodies to recombinant IA-2 and GAD65 may eventually replace ICA immunofluorescence for IDDM population screening.