947 resultados para Heart and kidney adaptations


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Shipping list no.: 87-541-P.

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I. Sonnets and minor poems. -- [II] The school of the heart.

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v. 1. Sonnets and minor poems.--v. 2. The school of the heart.

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Earlier eds. have title: The anatomy of the human body.

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First-2d editions by Maurice Lewison and Ellis B. Freilich.

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The conjugation of a lipoamino acid to the N-terminus of Gonadotropin releasing hormone (GnRH) produces a lipophilic peptide from which the parent GnRH peptide is released into solution on treatment with plasma and kidney enzyme preparation. Our findings show that one stereoisomer of the Laa is cleaved very rapidly, providing a bolus dose of the peptide while the opposite stereoisomer is cleaved much more slowly, providing prolonged elevation of peptide concentration. The Laa-Glu linkage appears to act as a two phase prodrug system. © 2005 Elsevier Ltd. All rights reserved.