999 resultados para Granville, A. B. (Augustus Bozzi), 1783-1872


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Previously, we reported that a 61-bp subgenomic HBV DNA sequence (designated as 15AB, nt 1855-1915) is a hot spot for genomic recombination and that a cellular protein binding to 15AB may be the putative recombinogenic protein. In the present study, we established the existence of a 15AB-like sequence in human and rat chromosomal DNA by Southern blot analysis. The 15AB-like sequence isolated from the rat chromosome demonstrated a 80.9% identity with 5'-CCAAGCTGTGCCTTGGGTGGC-3', at 1872-1892 of the hepatitis B virus genome, thought to be the essential region for recombination. Interestingly, this 15AB-like sequence also contained the pentanucleotide motifs GCTGG and CCAGC as an inverted repeat, part of the chi known hot spot for recombination in Escherichia coli. Importantly, a portion of the 15AB-like sequence is homologous (82.1%, 23/28 bp) to break point clusters of the human promyelocytic leukemia (PML) gene, characterized by a translocation [t(15;17)], and to rearranged mouse DNA for the immunoglobulin kappa light chain. Moreover, 15AB and 15AB-like sequences have striking homologies (12/15 = 80.0% and 13/15 = 86.7%, respectively) to the consensus sequence for topoisomerase II. Our present results suggest that this 15AB-like sequence in the rat genome might be a recombinogenic candidate triggering genomic instability in carcinogenesis.

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One folio-sized leaf containing a handwritten list of Commencement fees and salaries received by President Willard between 1783 and 1802. The paper includes the struck-out inscription "Cushing."

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This folder contains three letters originally sewn to the front inside cover of Volume 1 of Sewall's bound lectures (HUG 1782 Box 3). A fourth letter is still glued to the inside front cover and listed with the volume. The three letters consist of a letter from B. Kennicott to Stephen Sewall, May 14, 1771 and two letters written in French from Antoine Court de Gébelin to Stephen Sewall, one written on March 3, 1780, and the second received on November 18, 1783. The letter from Benjamin Kennicott acknowledges Sewall's letter to him and offers instructions for paying for a subscription to Kennicott's work. A portion of the missing text from Box 1 can be found in this folder.

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muʻallifuhu Shams al-Dīn Muḥammad ibnamzah ibn Muḥammad al-Fanārī.

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li-Muḥammad ʻĪsá ʻAskar.

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According to the colophon (f. 76r), written on 5 Shawwāl 860 AH [September 5, 1456 AD]. There is a note in a later hand that says, "Hādhā al-kitāb bi-khaal-muʼallif" (f. 75r).

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1- al-Durrah al-zāhirah bi-tamīn al-Buah al-fājirah / lil-Shaykh Qāsim (printed text, paginated 1-15; ff. 1r-8r) -- 2. Afal al-zād li-yawm al-maād fī al-ṣalāh wa-al-salām ʻalá khayr al-ʻibd (ff. 9r-28v) -- 3. On miracles of the Prophet (ff. 29r-32r) -- 4. Commentary on a verse from the Qurʼān (ff. 32v-34v) -- 5. Hādhihi Qaīdat Sayyidinā Muḥammad [A poem in praise of the Prophet] (f. 35r) -- 6. Hādhā Mawlid Sayyid al-awwalīn wa-al-ākhirīn Muḥammad ibn ʻAbd Allāh ibn ʻAbd al-Muṭṭalib, 25 Rabīʻ al-Awwal 1274 AH [November 12, 1857 AD] (ff. 36r-40v).

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Two gadoid fishes, Arctogadus glacialis and Boreogadus saida, often coexist (i.e. sympatric) in the fjords and shelf areas of the Arctic seas, where they likely share the same food resources. Diet composition from stomach contents, i.e. frequency of occurrence (FO) and Schoener's index (SI), and stable isotope signatures (d13C and d15N) in muscle of these sympatric gadoids were examined from two fjords in NE Greenland-Tyrolerfjord (TF, ~74°N, sill present) and Dove Bugt (DB, ~76°N, open). Twenty-three prey taxa and categories were identified and both gadoids ate mostly crustaceans. The SI values of 0.64-0.70 indicated possible resource competition, whereas FO differed significantly. A. glacialis fed mainly on the mysid Mysis oculata and other benthic-associated prey, whereas B. saida ate the copepod Metridia longa and other pelagic prey. Both diet and stable isotopes strongly suggest a spatial segregation in feeding habitat, with A. glacialis being associated with the benthic food web (mean d13C = -20.81 per mil, d15N = 14.92 per mil) and B. saida with the pelagic food web (mean d13C = -21.25 per mil, d15N = 13.64 per mil). The dietary differences and isotopic signals were highly significant in the secluded TF and less clear in the open DB, where prey and predators may be readily advected from adjacent areas with other trophic conditions. This is the first study on the trophic position of A. glacialis inferred from analyses of stable isotopes. The subtle interaction between the Arctic gadoids should be carefully monitored in the light of ocean warming and ongoing invasions of boreal fishes into the Arctic seas.